DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS

• US 20130296710A1
• Filed: 02/25/2013
• Published: 11/07/2013
• Est. Priority Date: 08/10/2008
• Status: Abandoned Application

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: ZUZAK, Karel J., CADEDDU, Jeffrey A., UFRET-VINCENTY, Rafael, FRANCIS, Robert P., LIVINGSTON, Edward
• Application Number:
  US13/776,105
• Publication Number:
  US 20130296710A1
• Time in Patent Office: Days
• US Class Current: 600/476
• CPC Class Codes: A61B 3/12 for looking at the eye fundus, e.g. ophthalmoscopes A61B3/13 takes precedence
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/0086 using infrared radiation
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/4064 Evaluating the brain A61B5/031, A61B5/369, A61B5/14553 take precedence
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/413 Monitoring transplanted tissue or organ, e.g. for possible rejection reactions after a transplant
• CPC Class Codes: A61B 5/4842 Monitoring progression or stage of a disease
• CPC Class Codes: G01J 2003/1213 Filters in general, e.g. dichroic, band
• CPC Class Codes: G01J 2003/1282 Spectrum tailoring
• CPC Class Codes: G01J 3/02 Details
• CPC Class Codes: G01J 3/0208 using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
• CPC Class Codes: G01J 3/021 using plane or convex mirrors, parallel phase plates, or particular reflectors
• CPC Class Codes: G01J 3/0229 using masks, aperture plates, spatial light modulators or spatial filters, e.g. reflective filters
• CPC Class Codes: G01J 3/0264 Electrical interface; User interface
• CPC Class Codes: G01J 3/10 Arrangements of light sources specially adapted for spectrometry or colorimetry
• CPC Class Codes: G01J 3/2803 using photoelectric array detector
• CPC Class Codes: G01J 3/2823 : Imaging spectrometer
• CPC Class Codes: G01N 21/31 : Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry G01N21/72 takes precedence
• CPC Class Codes: G01N 21/39 : using tunable lasers
• CPC Class Codes: G06T 2207/10036 : Multispectral image; Hyperspectral image

Abstract

A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target.

Claims

1-45. -45. (canceled)

46. :

A method of monitoring a tissue or an organ viability during periods of ischemia comprising the steps of;

forming a hyperspectral image of said tissue or said organ, wherein said hyperspectral image comprises a quantitative measure of oxygenation of said tissue or said organ;

calculating a length of time of said tissue or said organ viability based on said quantitative measure of oxygenation of said tissue or said organ.

47. :

The method according to claim 46, wherein said step of forming a hyperspectral image is performed with an apparatus comprising;

an illumination source adapted to output a light beam, said light beam illuminating said tissue or said organ;

a dispersing element arranged in said optical path and adapted to separate said light beam into a plurality of wavelengths;

a spatial light modulator adapted to tune said plurality of wavelengths into a spectrum;

an optical device comprising a detector and adapted to collect said spectrum reflected from said tissue or said organ and arranged in said optical path; and

,

a processor operatively connected to and adapted to control at least one of;

said illumination source;

said dispersing element;

said spatial light modulator;

said optical device; and

, said detector, said processor further adapted to output said hyperspectral image of said tissue or said organ,

wherein said dispersing element is arranged between said illumination source and said spatial light modulator, said spatial light modulator is arranged to transmit said spectrum to said tissue or said organ and said optical device is arranged in said optical path after said tissue or said organ.