ULTRASOUND APPARATUS AND METHODS TO MONITOR BODILY VESSELS

• US 20130303915A1
• Filed: 04/26/2013
• Published: 11/14/2013
• Est. Priority Date: 04/26/2012
• Status: Abandoned Application

• Current Assignee: dBMEDx Inc.
• Original Assignee: dBMEDx Inc.
• Inventors: Barnard, William L., Shine, David B.
• Application Number:
  US13/871,842
• Publication Number:
  US 20130303915A1
• Time in Patent Office: Days
• US Class Current: 600/449
• CPC Class Codes: A61B 5/1075 for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer A61B8/0858 takes precedence
• CPC Class Codes: A61B 8/02 Measuring pulse or heart rate
• CPC Class Codes: A61B 8/0891 for diagnosis of blood vessels
• CPC Class Codes: A61B 8/13 Tomography A61B8/10, A61B8/12 take precedence; tomography for radiation diagnosis A61B6/02
• CPC Class Codes: A61B 8/4236 characterised by adhesive patches
• CPC Class Codes: A61B 8/4254 using sensors mounted on the probe
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/4455 Features of the external shape of the probe, e.g. ergonomic aspects
• CPC Class Codes: A61B 8/4461 Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
• CPC Class Codes: A61B 8/4472 Wireless probes
• CPC Class Codes: A61B 8/461 Displaying means of special interest
• CPC Class Codes: A61B 8/462 characterised by constructional features of the display
• CPC Class Codes: A61B 8/468 allowing annotation or message recording
• CPC Class Codes: A61B 8/483 involving the acquisition of a 3D volume of data
• CPC Class Codes: A61B 8/488 involving Doppler signals
• CPC Class Codes: A61B 8/5207 involving processing of raw data to produce diagnostic data, e.g. for generating an image reconstruction G06T11/00
• CPC Class Codes: A61B 8/5223 for extracting a diagnostic or physiological parameter from medical diagnostic data for algorithms to analyse biomedical images G06T7/0012
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

An automated 3D ultrasound abdominal vessel monitor is capable of providing automated anatomical and physiological data on the large abdominal vessels, for example the Inferior Vena Cava (IVC). The 3D ultrasound abdominal vessel monitor includes one or more ultrasound transducers built into a housing or frame that in use sits on the upper abdomen, just below the ribcage. A disposable component can serve to secure the 3D ultrasound abdominal vessel monitor to the patient and provide a coupling medium between the 3D ultrasound abdominal vessel monitor and the skin of the patient.

Claims

1. A monitor to monitor an inferior vena cava over multiple respiratory cycles, the device comprising:

a housing;

an ultrasound system that includes an ultrasonic scan engine located at least partially in the housing and a processing subsystem communicatively coupled to the ultrasonic scan engine, which automatically detects a volume of the inferior vena cava in real time independent from heart rate; and

an output device carried by the housing and communicatively coupled to the processing subsystem to provide indications based at least in part on the detected volume of the inferior vena cava.

2. The monitor of claim 1 wherein the ultrasound system non-invasively detects a maximum diameter and a minimum diameter of the inferior vena cava across multiple respiratory cycles.

3. The monitor of claim 1 wherein the processing subsystem calculates the volume of the inferior vena cava across multiple respiratory cycles.

4. The monitor of claim 1 wherein the ultrasonic scan engine transmits a plurality of 2D ultrasound planes to form a 3D data set from which walls of the inferior vena cava are automatically detected so as to determine a size and the volume of the inferior vena cava in real time.

5. The monitor of claim 4 wherein the ultrasonic scan engine transmits the plurality of 2D ultrasound planes in transverse sections.

6. The monitor of claim 4 wherein the ultrasonic scan engine transmits the plurality of 2D ultrasound planes in sagittal sections.

7. The monitor of to claim 2 wherein the ultrasound system further monitors respiration, by monitoring changes in distance from at least one local landmark within a patient over time.

8. The monitor of claim 7 wherein the at least one local landmark is a spine of the patient.

9. The monitor of claim 7 wherein the ultrasound system measures respiration from 1-30 times per second in real-time.

10. The monitor of claim 1 wherein the ultrasound system non-invasively measures a diameter of the inferior vena cava in multiple orientations around the inferior vena cava.

11. The monitor of claim 1 wherein the ultrasound system non-invasively measures a cross-sectional area of the inferior vena cava.

12. The monitor of claim 1 wherein the ultrasound system non-invasively measures a variation in diameter rotationally around the inferior vena cava.

13. The monitor of claim 1 wherein the processing subsystem assesses a roundness of the inferior vena cava by comparing multiple diameter measurements at different cross-sections in real time to differentiate collapse from simply reduced diameter.

14. The monitor of claim 1, further comprising:

a self-adhering structure to facilitate positioning the housing on an abdomen of a patient without applying pressure to the abdomen relative to one or more internal organs and vessels.

15. The monitor of claim 1 wherein the self-adhering structure can include disposable adhesive pads.

16. The monitor of claim 1 wherein the housing includes self-locating structure that conforms to a subxiphoid region.

17. The monitor of claim 16 wherein the self-locating structure includes a triangular shape which mirrors an arch formed by a base of a number of ribs and a xiphoid process of a patient.

18. The monitor of claim 1 wherein the processing subsystem compares a diameter of the inferior vena cava of a patient and a diameter of an aorta of the patient and calculates a ratio.

19. The monitor of claim 1 wherein the output device comprises a display, and the display presents a numerical value indicative of a relative change in diameter of the IVC.

20. The monitor of claim 19 wherein the display further presents a graphical representation of a relative change in diameter of the IVC over time.

21. The monitor of claim 1 wherein the output device comprises a display, and the display presents only a CI-IVC value and a heart rate value.

22. The monitor of claim 1 wherein the output device comprises a display, the display presents only a CI-IVC value, a heart rate value, and a respiration rate value.

23. The monitor of claim 1 wherein the housing includes a substantially flat upper portion and partially cylinderical lower portion, the lower portion which is proximate a patient during use.

24. The monitor of claim 23 wherein at least a portion of at least the ultrasonic scan engine is rotatable mounted in the lower portion of the housing, and further comprising:

a drive subsystem coupled to drivingly rotate the at least portion of at least the ultrasonic scan engine about a rotational axis.

25. The monitor of claim 23 wherein the upper portion of the housing has a pentagonal profile.

26. A method of automatically calculating indices of a patient for clinical use, comprising:

positioning a monitoring device on an abdomen of the patient;

non-invasively obtaining at least one of a minimum diameter and a maximum diameter of at least one of an aorta or an inferior vena cava of the patient with the monitoring device; and

automatically calculating at least one of an CI-IVC ([max IVC−

min IVC]/max IVC) or an IVC/Aorta ratio based on the obtained values.

27. A method of titrating hemodialysis, comprising:

positioning a monitoring device on an abdomen of a patient;

non-invasively obtaining at least one of a minimum diameter and a maximum diameter of an inferior vena cava with the monitoring device; and

titrating hemodialysis based on the obtained at least one of the minimum or the maximum diameter.

28. A method of monitoring an inferior vena cava, comprising:

positioning a monitoring device on an abdomen of a patient; and

scanning the inferior vena cava continuously to allow a 3D reconstruction of vessel diameter and behavior over time.

29. A monitor to monitor an inferior vena cava over multiple respiratory cycles, the device comprising:

a housing;

an ultrasound system that includes an ultrasonic scan engine located at least partially in the housing and a processing subsystem communicatively coupled to the ultrasonic scan engine, which automatically detects a volume of the inferior vena cava in real time independent from heart rate; and

a display carried by the housing and commuicatively coupled to the processing subsystem to provide visual indications based at least in part on the detected volume of the inferior vena cava.

30. The monitor of claim 29 wherein the display presents a numerical value indicative of a relative change in diameter of the IVC.

31. The monitor of claim 29 wherein the display presents only a CI-IVC value and a heart rate value.

32. The monitor of claim 29 wherein the display presents only a CI-IVC value, a heart rate value, and a respiration rate value.

33. The monitor of claim 29 wherein the display presents only numerical information without any anatomical images.