PULMONARY PULSE OXIMETRY METHOD FOR THE MEASUREMENT OF OXYGEN SATURATION IN THE MIXED VENOUS BLOOD
First Claim
1. A method for obtaining diagnostic information relating to the lungs of a subject, the method comprising the steps of:
- (a) directing into tissue of the lungs of the subject light of a first wavelength;
(b) detecting part of said light that has passed primarily through microcirculatory tissue of the lungs and generating a signal which is a function of intensity of the detected light; and
(c) processing said signal to derive a PPG curve for pulmonary microcirculatory arteries.
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Accused Products
Abstract
A method for obtaining diagnostic information relating to the lungs of a subject includes directing into tissue of the lungs of the subject light of a first wavelength and detecting part of the light that has passed primarily through microcirculatory tissue of the lungs and generating a signal which is a function of intensity of the detected light. The signal is then processed to derive a PPG curve for pulmonary microcirculatory arteries. The method is implemented using various locations for a light source and a detector, including various combinations of positioning on the thoracic wall, insertion into the esophagus, and in some cases, insertion of a probe through the thoracic wall to a position adjacent to the pulmonary pleura. Use of two different wavelengths allows derivation of mixed venous blood oxygen saturation.
42 Citations
33 Claims
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1. A method for obtaining diagnostic information relating to the lungs of a subject, the method comprising the steps of:
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(a) directing into tissue of the lungs of the subject light of a first wavelength; (b) detecting part of said light that has passed primarily through microcirculatory tissue of the lungs and generating a signal which is a function of intensity of the detected light; and (c) processing said signal to derive a PPG curve for pulmonary microcirculatory arteries. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A device for determining oxygen saturation SvO2 in the blood of the pulmonary microcirculatory arteries of a subject, the device comprising the components:
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(a) a first light source of a first wavelength in the infrared; (b) a second light source of a second wavelength in the infrared, different from said first wavelength; (c) a light delivering element configured to direct the light of the two wavelengths into the same tissue of the lungs; (d) a detector configured to detect part of the light for each of said first and second wavelengths that has passed through microcirculatory tissue of the lungs and to generate two signals which are functions of intensities of the detected light for each of said first and second wavelengths; and (e) a processing system configured to process said signals to derive PPG curves for pulmonary microcirculatory arteries and to process said PPG curves for deriving a ratio R between values of a parameter related to relative changes in light transmission for said first and second wavelengths, and determining from said ratio R the oxygen saturation in the blood of the pulmonary microcirculatory arteries; wherein said first and second light source are in contact with a first location on the thoracic wall of the subject, and said detector is in contact with a second location on the thoracic wall of the subject wherein said second location is at least 15 millimeters from said first location. - View Dependent Claims (32, 33)
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Specification