SATIATION DEVICES AND METHODS

• US 20130310727A1
• Filed: 01/04/2013
• Published: 11/21/2013
• Est. Priority Date: 08/27/2001
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Barosense, Inc. (Boston Scientific Scimed Incorporated)
• Inventors: Stack, Richard, Glenn, Richard, Moody, Trevor, Silverstein, Fred, Every, Nathan, Eubanks, William Jr.
• Granted Patent: US 9,254,214 B2
• Time in Patent Office: Days
• US Class Current: 604/9
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets
• CPC Class Codes: A61F 2002/045 Stomach, intestines
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 5/0069 in the wall of the stomach
• CPC Class Codes: A61F 5/0076 preventing normal digestion, e.g. Bariatric or gastric sleeves
• CPC Class Codes: A61F 5/0079 Pyloric or esophageal obstructions

Abstract

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

Claims

1. A duodenal absorption barrier for use in limiting absorption of food in the small intestine of a human subject, comprising:

an elongate polymeric sleeve at least 20 cm in length and extending between proximal and distal open ends, with a radial constriction therebetween, said sleeve having an exterior duodenum-contacting surface adapted for contacting the surrounding wall of the subject'"'"'s duodenum, barbs or scales disposed on said exterior surface of the sleeve, and disposed entirely within the sleeve, a self-expandable wire structure adapted, in its expanded form, and with the duodenal absorption barrier positioned entirely within the small intestine of the subject, to exert an outward pressure of the exterior surface of the sleeve against the surrounding walls of the duodenum, thereby pressing the barbs or scales disposed on the exterior surface against the surrounding duodenal walls, to anchor the entire duodenal absorption barrier within the duodenum, where the sleeve acts as an absorption barrier within the duodenum.

2. The duodenal absorption barrier of claim 1, wherein the self-expandable wire structure includes an expandable ring.

3. The duodenal absorption barrier of claim 2, wherein the self-expandable wire structure includes a plurality of rings spaced along the length of the sleeve.

4. The duodenal absorption barrier of claim 1, wherein the sleeve has scales disposed on its exterior surface, oriented to prevent movement of the duodenal absorption barrier within the duodenum.

5. The duodenal absorption barrier of claim 1, wherein the radial constriction between the proximal and distal ends occurs at an interface between a larger-diameter proximal section and a small-diameter distal section.