PROSTHETIC HEART VALVE DEVICES, PROSTHETIC MITRAL VALVES AND ASSOCIATED SYSTEMS AND METHODS
First Claim
1. A method for replacing a native mitral heart valve having a native annulus and native leaflets with a prosthetic heart valve device having a valve support, a valve coupled to the valve support, and an anchoring member with a fixation portion having a first cross-sectional shape in a fully expanded an unbiased condition, a connection structure having an inner portion coupled to the valve support and an outer portion coupled to the fixation portion, and a transition zone from which the fixation portion extends from the outer portion of the connection structure, the method comprising:
- delivering the prosthetic heart valve in a low-profile delivery configuration into a chamber of the heart through a blood vessel or through a conduit extending through a wall of the heart;
positioning the prosthetic heart valve device near the native mitral valve; and
expanding the prosthetic heart valve device to an expanded configuration in which at least a portion of the connection structure extends in a first direction transverse to a direction of blood flow through the native mitral valve and the fixation portion extends from the transition zone in a second direction different than the first direction, wherein the fixation portion engages inward-facing surface of the native leaflets.
2 Assignments
0 Petitions
Accused Products
Abstract
Devices and methods for implantation at a native mitral valve having a non-circular annulus and leaflets. One embodiment of the device includes a valve support having a first region configured to be attached to a prosthetic valve with a plurality of prosthetic leaflets and a second region, and an anchoring member having a longitudinal dimension with a first portion configured to contact tissue at the non-circular annulus, a second portion configured to be attached to the valve support, and a lateral portion transverse to the longitudinal dimension between the first portion and the second portion. The anchoring member and the valve support are configured to move from a low-profile configuration to an expanded configuration in which a shape of the first region of the valve support is at least partially independent of a shape of the first portion of the anchoring member.
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Citations
30 Claims
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1. A method for replacing a native mitral heart valve having a native annulus and native leaflets with a prosthetic heart valve device having a valve support, a valve coupled to the valve support, and an anchoring member with a fixation portion having a first cross-sectional shape in a fully expanded an unbiased condition, a connection structure having an inner portion coupled to the valve support and an outer portion coupled to the fixation portion, and a transition zone from which the fixation portion extends from the outer portion of the connection structure, the method comprising:
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delivering the prosthetic heart valve in a low-profile delivery configuration into a chamber of the heart through a blood vessel or through a conduit extending through a wall of the heart; positioning the prosthetic heart valve device near the native mitral valve; and expanding the prosthetic heart valve device to an expanded configuration in which at least a portion of the connection structure extends in a first direction transverse to a direction of blood flow through the native mitral valve and the fixation portion extends from the transition zone in a second direction different than the first direction, wherein the fixation portion engages inward-facing surface of the native leaflets. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for replacing a native heart valve having an annulus and leaflet extending from the annulus, comprising:
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positioning a prosthetic heart valve device at a native mitral valve location in a heart of a human, wherein the prosthetic heart valve device comprises an anchoring member and a valve support, the anchoring member includes a connection structure and a fixation portion, the connection structure includes an inner end at the valve support and an outer end, the fixation portion extends from the outer end of the connection structure, and the fixation structure includes an outwardly-facing surface configured to extend from the connection structure at a first angle in an expanded unbiased state; and expanding the prosthetic heart valve device such that at least a portion of the connection structure flares outwardly in a transverse direction relative to blood flow through the native mitral valve, the fixation portion deflects relative to the outer end of the connection structure to extend from the connection structure at a second angle different than the first angle as the outwardly-facing surface of the fixation portion contacts tissue at or downstream of the native annulus, and an upstream portion of the valve support is spaced inwardly apart from the fixation portion. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A method for replacement of a native heart valve having an annulus and leaflets coupled to the annulus, the method comprising:
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positioning a prosthetic heart valve device including an anchoring member and a valve support at a native mitral valve location in a heart of the patient, wherein the anchoring member has a first portion and a second portion, and the valve support has a first region and a second region; and expanding the anchoring member and the valve support while the second portion of the anchoring member is coupled to the second region of the valve support such that the first portion of the anchoring member engages tissue at or downstream of the annulus and at least partially adapts to a shape of the annulus at the native mitral valve location; wherein, upon expansion, the first region of the valve support is spaced inwardly apart from the first portion of the anchoring member and the first region of the valve support holds a prosthetic valve having prosthetic leaflets such that the prosthetic leaflets contact each other sufficiently to inhibit backflow through the prosthetic valve after the first portion of the anchoring member has adapted to the shape of the annulus of the native mitral valve. - View Dependent Claims (28, 29, 30)
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Specification