CARDIAC PULSE COEFFICIENT OF VARIATION AND BREATHING MONITORING SYSTEM AND METHOD FOR EXTRACTING INFORMATION FROM THE CARDIAC PULSE
First Claim
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1. A method of measuring awareness in a human subject, comprising the steps of:
- using a sensor and cardiac pulse measurement hardware, measuring a cardiac pulse at a location on the subject, the measurement providing pulse signals;
using a computer apparatus, applying a method to the pulse signals comprising eliminating noise from the pulse signals by using an error detecting algorithm to remove high magnitude pulse noise and retain lower magnitude data before the Coefficient of Variation (CoV) is calculated, and applying the pulse Coefficient of Variation (CoV) method to the measured pulse signals, to obtain Coefficient of Variation (CoV); and
evaluating the awareness of the subject based on the retained low Coefficient of Variation (CoV) data,wherein high amplitude Coefficient of Variation (CoV) is indicated as greater than 7% CoV, andwherein low Coefficient of Variation (CoV) data is indicated as less than 7% CoV.
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Abstract
A system and method to extract and measure awareness and a breathing rate information from the cardiac pulse uses plethysmographic and oximeter sensors. The information finds applications in patient monitoring during surgery, intensive care, sleep therapy, and sleep detection in critical operations of airplanes, trucks, automobiles, trains, and in biofeedback therapy.
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Citations
20 Claims
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1. A method of measuring awareness in a human subject, comprising the steps of:
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using a sensor and cardiac pulse measurement hardware, measuring a cardiac pulse at a location on the subject, the measurement providing pulse signals; using a computer apparatus, applying a method to the pulse signals comprising eliminating noise from the pulse signals by using an error detecting algorithm to remove high magnitude pulse noise and retain lower magnitude data before the Coefficient of Variation (CoV) is calculated, and applying the pulse Coefficient of Variation (CoV) method to the measured pulse signals, to obtain Coefficient of Variation (CoV); and evaluating the awareness of the subject based on the retained low Coefficient of Variation (CoV) data, wherein high amplitude Coefficient of Variation (CoV) is indicated as greater than 7% CoV, and wherein low Coefficient of Variation (CoV) data is indicated as less than 7% CoV. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A device for implementing a method of measuring awareness in a human subject, comprising the steps of:
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a sensor and cardiac pulse measurement hardware configured to measure a cardiac pulse at a location on the subject, the measurement providing time domain pulse signals; and a computer apparatus operatively connected to the sensor by way of an input/output communications bus, the computer apparatus further comprised of a processor, memory, and an information storage facility having stored therein software executable to cause the computer to A) transform the time domain pulse signals to a frequency domain, including i) extracting magnitudes of dominant pulse frequencies to obtain pulse data (107), ii) computing a running standard deviation of the magnitudes of the dominant pulse frequencies (112), iii) dividing the computed running standard deviation by a corresponding moving average to obtain the pulse coefficient of variation (112), and iv) generate a statistically enhanced spectrum of the pulse signals in the frequency domain, B) evaluate the awareness of the subject based on the obtained pulse coefficient of variation, and C) evaluate a breathing rate of the subject from peaks detected from said statistically enhanced spectrum, thereby to further evaluate the awareness of the subject.
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Specification