HIGH RESOLUTION HIGH CONTRAST MRI FOR FLOWING MEDIA

• US 20130328559A1
• Filed: 10/16/2012
• Published: 12/12/2013
• Est. Priority Date: 06/06/2012
• Status: Active Grant

• Current Assignee: Aspect Imaging Ltd.
• Original Assignee: Aspect Imaging Ltd.
• Inventors: RAPOPORT, Uri
• Granted Patent: US 9,182,461 B2
• Time in Patent Office: Days
• US Class Current: 324/309
• CPC Class Codes: G01N 24/084 Detection of potentially hazardous samples, e.g. toxic samples, explosives, drugs, firearms, weapons
• CPC Class Codes: G01R 33/32 Excitation or detection systems, e.g. using radio frequency signals
• CPC Class Codes: G01R 33/445 MR involving a non-standard magnetic field B0, e.g. of low magnitude as in the earth's magnetic field or in nanoTesla spectroscopy, comprising a polarizing magnetic field for pre-polarisation, B0 with a temporal variation of its magnitude or direction such as field cycling of B0 or rotation of the direction of B0, or spatially inhomogeneous B0 like in fringe-field MR or in stray-field imaging
• CPC Class Codes: G01R 33/56 Image enhancement or correction, e.g. subtraction or averaging techniques , e.g. improvement of signal-to-noise ratio and resolution

Abstract

An MRI device for providing high-contrast, high-resolution images of a fluid. The device includes: an envelope for at least partially confining the fluid; a plurality of magnets located at least partially around the envelope; and a CPU to process the images, including a computer readable medium containing instructions for generating at least one third image superimposing at least one image of the first images with at least one image of the second images, whereby a high-contrast, high-resolution real-time continuous images of the fluid is obtained.

Claims

1. An MRI based method for providing high contrast high resolution images of a fluid, comprising:

a. providing an envelope for least partially confining said fluid;

b. providing a plurality of magnets located at least partially around said envelope, said assembly comprising

i. a least one first magnet configured to provide a high magnetic field for generating multiple time-resolved one or more first images at high resolution of at least a portion of said fluid; and

ii. a least one second magnet configured to provide a low magnetic field for generating multiple time-resolved one or more second images at high contrast of at least portion of same said fluid;

wherein at least one image of said first images and at least one image of said second images being generated in a time no greater than approximately the time between two first images;

c. providing a CPU to process said images comprising a computer readable medium containing instructions for generating at least one third image superimposing at least one image of said first images with at least one image of said second images;

d. generating multiple time resolved one or more first images at high resolution of at least a portion of said fluid;

e. generating multiple time resolved one or more second images at high contrast of at least portion of same said fluid; and

f. superimposing at least one image of said first images with at least one image of said second images

whereby a high-contrast, high resolution real-time continuous image of said fluid is obtained.

2. The MRI based method of claim 1, comprising an additional step of selecting said at least one first magnet to be of 2 Tesla and lower.

3. The MRI based method of claim 1, comprising an additional step of selecting said at least one first magnet to be of 2 Tesla and higher.

4. The MRI based method of claim 1, comprising an additional step of selecting said at least one first magnet from a group consisting of permanent magnets, electromagnets, superconducting magnets, and any combination thereof.

5. The MRI based method of claim 1, comprising an additional step of selecting said at least one second magnet to be of 2 Tesla and lower.

6. The MRI based method of claim 1, comprising an additional step of selecting said at least one second magnet to be of 2 Tesla and higher.

7. The MRI based method of claim 1, comprising an additional step of selecting said at least one second magnet from a group consisting of permanent magnets, electromagnets, superconducting magnets, and any combination thereof.

8. The MRI based method of claim 1, comprising an additional step of providing said at least one first magnet and said at least one second magnet as a single at least one magnet.

9. The MRI based method of claim 1, comprising an additional step of having the angle between a perpendicular to the direction of flow and said high magnetic field not the same as the angle between said perpendicular to the direction of flow and said low magnetic field.

10. The MRI based method of claim 1, comprising an additional step of selecting an integrated MRI device comprising both said high magnetic field magnets and said low magnetic field magnets.

11. The MRI based method of claim 1, comprising an additional step of selecting said MRI device comprising two MRI devices, one providing the high magnetic field magnets and one providing the low magnetic field magnets.

12. The MRI based method of claim 1, comprising an additional step of selecting a duty cycle for said high magnetic field magnets greater than approximately 50% and a duty cycle for said low magnetic fields magnets less than approximately 50%.

13. The MRI based method of claim 1, comprising an additional step of selecting said envelope from a group consisting of a pipe, a duct, a tunnel, a conduit, a tube, a conveyor, a channel, a passage, and any combination thereof.

14. The MRI based method of claim 1, comprising an additional step of forming said envelope as an integral part of at least one MRI device.

15. The MRI based method of claim 1, comprising an additional step of selecting said fluid from a group consisting of a liquid, a gas, a slurry, a liquid containing particulates, a gas containing particulates, a gel, a sol, a suspension, a solution, a dispersion, a colloid, a mixture, an emulsion, an aerosol, a liquid containing solid objects, a gas containing solid objects, and any combination thereof.

16. The MRI based method of claim 1, comprising an additional step of providing said fluid within the fluid process stream in a production process.

17. The MRI based method of claim 16, comprising an additional step of selecting said production process in an industrial area, said industrial area a member of a group consisting of the pharmaceuticals, food production, beverage production, chemical refining, chemical processing, medical products, biological products, metal casting, metal refining, desalination, fluid purification, and sewage processing.

18. The MRI based method of claim 17, comprising an additional step of selecting water as the fluid purified in said fluid purification.

19. The MRI based method of claim 1, comprising an additional step of providing said fluid within a bypass stream from a production line.

20. The MRI based method of claim 1, comprising an additional step of providing said fluid in the fluid process stream within a batch process.

21. The MRI based method of claim 1, comprising an additional step of providing said fluid within an engine or combustion chamber.

22. The MRI based method of claim 1, comprising an additional step of providing said fluid as the effluent from said engine or combustion chamber.

23. The MRI based method of claim 1, comprising an additional step of providing said fluid as some fraction of the effluent from said engine or combustion chamber.

24. The MRI based method of claim 1, comprising an additional step of selecting a fluid used in fertility treatments.

25. The MRI based method of claim 1, comprising an additional step of selecting a fluid used for artificial insemination.

26. The MRI based method of claim 1, comprising an additional step of selecting a fluid containing liposomes.

27. The MRI based method of claim 1, comprising an additional step of selecting a fluid which is part of an air curtain.

28. The MRI based method of claim 1, comprising an additional step of selecting a fluid which is a polymeric melt.

29. The MRI based method of claim 28, comprising an additional step of selecting said polymeric melt from a group consisting of rubbers, polyesters, polyamides, polypropylenes, polyethylenes, polyurethanes, and any combination thereof.

30. The MRI based method of claim 1, comprising an additional step of integrating analysis and production of a product.

31. The MRI based method of claim 30, wherein least a part of said step of integrating analysis and production of a product complies with a NeSSI specification.

32. The MRI based method of claim 30, wherein at least a part of step of integrating analysis and production of a product complies with ANSI/ISA SP76.00.2002 miniature, modular mechanical standard specifications.

33. The MRI based method of claim 1, comprising an additional step of selecting a fluid within the body of a living subject as said flowing matter.

34. The MRI based method of claim 33, comprising an additional step of passing said fluid from the body of a living subject, through said envelope, and returning it to said living subject.

35. The MRI based method of claim 1, for imaging at least one first and at least one second image features;

comprising an additional step of adapting said image processor to render said image by a Boolean method of correlating or combining said at least one first and at least one second image features.

36. The MRI based method of claim 35, comprising an additional step of selecting said Boolean operators of said Boolean method from the group consisting of OR, AND, NOT, EXCLUSIVE OR and any combination thereof.

37. The MRI-based method of claim 1, comprising an additional step of selecting the fluid from a group consisting of potable water, sewage, irrigation water, sea water, river water, lake water, industrial effluent, farm effluent, effluent from human habitation, road runoff, blood, lymph, a beverage, cleaning fluid, and any combination thereof.