MECHANICALLY ACTUATED FLUID INFUSION DEVICE

• US 20130345633A1
• Filed: 06/26/2012
• Published: 12/26/2013
• Est. Priority Date: 06/26/2012
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: Chong, Colin A.
• Granted Patent: US 9,333,292 B2
• Time in Patent Office: Days
• US Class Current: 604/132
• CPC Class Codes: A61M 2005/14506 mechanically driven, e.g. spring or clockwork
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/145 using pressurised reservoirs, e.g. pressurised by means of pistons
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/148 flexible, e.g. independent bagsA61M5/155 takes precedence
• CPC Class Codes: A61M 5/152 pressurised by contraction of elastic reservoirs containers for dispensing contents by contraction of an elastic bag provided therein, in general B65D83/0061
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28

Abstract

A fluid infusion device, for delivery of a medication fluid to the body of a user, includes a housing, a fluid reservoir for the medication fluid, a dosing mechanism, an infusion component, and a mechanical actuator. The fluid reservoir and the dosing mechanism are located in the housing, and the dosing mechanism is coupled to receive the medication fluid from the fluid reservoir. The dosing mechanism has an adjustable fluid chamber that defines a variable dosage volume. The infusion component is coupled to the dosing mechanism to receive the medication fluid from the adjustable fluid chamber. The mechanical actuator is coupled to the dosing mechanism such that operation of the mechanical actuator causes the medication fluid to be expelled from the adjustable fluid chamber to the infusion component.

Claims

1. A fluid infusion device for delivery of a medication fluid to the body of a user, the fluid infusion device comprising:

a housing;

a fluid reservoir for the medication fluid, wherein the fluid reservoir is located in the housing;

a dosing mechanism located in the housing and coupled to the fluid reservoir to receive the medication fluid from the fluid reservoir, the dosing mechanism comprising an adjustable fluid chamber that defines a variable dosage volume;

an infusion component coupled to the dosing mechanism to receive the medication fluid from the adjustable fluid chamber; and

a mechanical actuator coupled to the dosing mechanism, wherein operation of the mechanical actuator causes the medication fluid to be expelled from the adjustable fluid chamber to the infusion component.

2. The fluid infusion device of claim 1, wherein the dosing mechanism and the mechanical actuator form an integrated subassembly.

3. The fluid infusion device of claim 2, wherein the mechanical actuator comprises a plunger for the adjustable fluid chamber.

4. The fluid infusion device of claim 1, further comprising a valve assembly between the fluid reservoir and the dosing mechanism, wherein the valve assembly inhibits flow of the medication fluid from the adjustable fluid chamber to the fluid reservoir.

5. The fluid infusion device of claim 1, further comprising a valve assembly between the fluid reservoir and the infusion component, wherein the valve assembly inhibits flow of the medication fluid from the fluid reservoir directly to the infusion component.

6. The fluid infusion device of claim 1, further comprising a valve assembly between the dosing mechanism and the infusion component, wherein the valve assembly inhibits flow of the medication fluid from the infusion component to the dosing mechanism.

7. The fluid infusion device of claim 1, further comprising a biasing element for the mechanical actuator, wherein the biasing element biases the mechanical actuator into a nominal pre-delivery position.

8. The fluid infusion device of claim 7, wherein the biasing element moves the mechanical actuator into the nominal pre-delivery position following each operation of the mechanical actuator.

9. The fluid infusion device of claim 8, wherein the fluid reservoir refills the adjustable fluid chamber with the medication fluid in response to the biasing element moving the mechanical actuator into the nominal pre-delivery position.

10. The fluid infusion device of claim 1, wherein the fluid reservoir comprises a self-contracting reservoir bag.

11. The fluid infusion device of claim 10, wherein the self-contracting reservoir bag comprises a resilient balloon.

12. The fluid infusion device of claim 10, wherein the self-contracting reservoir bag comprises a resilient bellows.

13. The fluid infusion device of claim 1, wherein the fluid reservoir comprises:

a resilient bladder; and

a structure operatively coupled to the resilient bladder to impart a compressive force to the resilient bladder.

14. The fluid infusion device of claim 13, wherein the structure comprises a spring loaded platform.

15. The fluid infusion device of claim 14, wherein the spring loaded platform squeezes the resilient bladder against an interior surface of the housing.

16. The fluid infusion device of claim 1, wherein the fluid reservoir comprises:

a barrel body having a fluid delivery end and a base opposite the fluid delivery end;

a plunger located in the barrel body; and

a biasing element located in the barrel body between the plunger and the base of the barrel body, wherein the biasing element biases the plunger toward the fluid delivery end.

17. The fluid infusion device of claim 1, wherein the adjustable fluid chamber is adjustable in discrete steps that define a plurality of predetermined and calibrated dosage volumes for the dosing mechanism.

18. The fluid infusion device of claim 1, wherein the infusion component is integrated with the housing to accommodate direct attachment of the fluid infusion device to the body of the user.

19. The fluid infusion device of claim 1, wherein the infusion component comprises:

an infusion set having a cannula for subcutaneous insertion into the body of the user, and having an adhesive element to accommodate direct attachment of the infusion set to the body of the user; and

tubing coupled between the infusion set and the adjustable fluid chamber, the tubing establishing a fluid flow path from the adjustable fluid chamber to the infusion set.

20. The fluid infusion device of claim 1, further comprising:

a fill port accessible from outside the housing, wherein the fill port is fluidly coupled to the fluid reservoir to facilitate filling of the fluid reservoir with the medication fluid.

21. The fluid infusion device of claim 20, wherein the fill port is self-sealing.

22. A fluid infusion device for delivery of a medication fluid to the body of a user, the fluid infusion device comprising:

a housing;

a fluid reservoir for the medication fluid, wherein the fluid reservoir is located in the housing, and wherein the medication fluid in the fluid reservoir is maintained under positive pressure;

a valve assembly located in the housing and coupled to the fluid reservoir;

a dosing mechanism located in the housing and coupled to the fluid reservoir via the valve assembly, the dosing mechanism comprising an adjustable fluid chamber that defines a user-selectable dosage volume, and the dosing mechanism comprising a mechanical actuator; and

a fluid conduit coupled to the dosing mechanism via the valve assembly, wherein at least a portion of the fluid conduit is external to the housing when the fluid infusion device is deployed for operation;

wherein;

application of an actuation force to the mechanical actuator initiates a fluid delivery operation;

removal of the actuation force from the mechanical actuator initiates a refill operation;

during the fluid delivery operation, the valve assembly allows the medication fluid to flow from the adjustable fluid chamber into the fluid conduit for delivery to the body of the patient, while inhibiting flow of the medication fluid from the adjustable fluid chamber into the fluid reservoir; and

during the refill operation, the valve assembly allows the medication fluid to flow from the fluid reservoir into the adjustable fluid chamber, while inhibiting flow of the medication fluid from the fluid reservoir into the fluid conduit.

23. The fluid infusion device of claim 22, wherein:

the valve assembly inhibits flow of the medication fluid from the fluid conduit to the fluid reservoir; and

the valve assembly inhibits flow of the medication fluid from the fluid conduit to the adjustable fluid chamber.

24. The fluid infusion device of claim 22, wherein the fluid reservoir comprises a self-contracting reservoir bag.

25. The fluid infusion device of claim 22, wherein the fluid reservoir comprises:

a resilient bladder; and

a structure operatively coupled to the resilient bladder to impart a compressive force to the resilient bladder.

26. The fluid infusion device of claim 22, wherein the fluid reservoir comprises:

a barrel body having a fluid delivery end and a base opposite the fluid delivery end;

a plunger located in the barrel body; and

a biasing element located in the barrel body between the plunger and the base of the barrel body, wherein the biasing element biases the plunger toward the fluid delivery end.

27. The fluid infusion device of claim 22, wherein the adjustable fluid chamber is adjustable in discrete steps that define a plurality of predetermined and calibrated dosage volumes.

28. The fluid infusion device of claim 22, further comprising an adhesive patch having a first side affixed to the housing and a second side for attachment to the body of the patient.

29. The fluid infusion device of claim 22, further comprising a fill port accessible from outside the housing, wherein:

the fill port is fluidly coupled to the fluid reservoir to facilitate filling of the fluid reservoir with the medication fluid during a filling operation; and

during the filling operation, the valve assembly inhibits flow of the medication fluid from the fluid reservoir to the fluid conduit.

30. A fluid infusion device for delivery of a medication fluid to the body of a user, the fluid infusion device comprising:

a housing;

a fluid reservoir to maintain the medication fluid under positive pressure, wherein the fluid reservoir is located in the housing;

a valve assembly located in the housing and coupled to the fluid reservoir;

a dosing mechanism located in the housing and coupled to the fluid reservoir via the valve assembly, the dosing mechanism comprising a mechanical actuator to adjust a fluid chamber of the dosing mechanism such that the fluid chamber defines a user-selectable dosage volume; and

a fluid delivery conduit coupled to the dosing mechanism via the valve assembly;

wherein;

in response to application of force to the mechanical actuator, the medication fluid in the fluid chamber is expelled through the fluid delivery conduit, while the valve assembly inhibits flow of the medication fluid from the fluid chamber to the fluid reservoir; and

in response to removal of the force, the mechanical actuator automatically retracts to refill the fluid chamber with the medication fluid from the fluid reservoir, while the valve assembly inhibits flow of the medication fluid from the fluid reservoir to the fluid delivery conduit and inhibits fluid flow from the fluid delivery conduit to the fluid chamber.

31. The fluid infusion device of claim 30, wherein the user-selectable dosage volume is adjustable in discrete steps that define a plurality of predetermined and calibrated dosage volumes.

32. The fluid infusion device of claim 30, wherein:

the user-selectable dosage volume is adjusted in response to rotation of the mechanical actuator about a major longitudinal axis; and

the mechanical actuator is actuated in response to application of the force in a direction aligned with the major longitudinal axis.

33. The fluid infusion device of claim 30, wherein the fluid reservoir comprises a self-contracting reservoir bag.

34. The fluid infusion device of claim 30, wherein the fluid reservoir comprises:

a resilient bladder; and

a structure operatively coupled to the resilient bladder to impart a compressive force to the resilient bladder.

35. The fluid infusion device of claim 30, wherein the fluid reservoir comprises:

a barrel body having a fluid delivery end and a base opposite the fluid delivery end;

a plunger located in the barrel body; and

a biasing element located in the barrel body between the plunger and the base of the barrel body, wherein the biasing element biases the plunger toward the fluid delivery end.

36. The fluid infusion device of claim 30, further comprising an adhesive patch having a first side affixed to the housing and a second side for attachment to the body of the patient.