METHOD AND APPARATUS FOR DETECTION AND MANAGEMENT OF AIR-IN-LINE

• US 20130345658A1
• Filed: 06/24/2012
• Published: 12/26/2013
• Est. Priority Date: 06/24/2012
• Status: Active Grant

• Current Assignee: Zevex (Moog Incorporated)
• Original Assignee: Zevex (Moog Incorporated)
• Inventors: Juretich, Jeffery T., Browne, Aidan, Gupta, Ramji, Martel, Daniel A.
• Granted Patent: US 9,408,968 B2
• Time in Patent Office: Days
• US Class Current: 604/500
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2005/16868 Downstream occlusion sensors
• CPC Class Codes: A61M 2005/16872 Upstream occlusion sensors
• CPC Class Codes: A61M 5/14232 Roller pumps
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/36 with means for eliminating or preventing injection or infusion of air into body dialysis systems, blood oxygenators A61M1/14; haemofiltration equipment A61M1/34; automatic tube cut-off A61M39/281
• CPC Class Codes: A61M 5/365 Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626

Abstract

In an infusion pump operable to deliver fluid to a patient at a programmed therapy flow rate, air-in-line sensing is improved by commanding the pumping mechanism to deliver a bolus volume of fluid at a flow rate higher than the therapy flow rate when an uninterrupted volume of air is detected that exceeds a first threshold. In many cases, the bolus will be effective to clear microbubbles from an observation zone of the air-in-line sensor to avoid an air-in-line alarm condition. If the uninterrupted volume of air continues to grow beyond a second threshold in spite of the bolus, then an alarm may be triggered. The invention reduces false alarms.

Claims

1. A method of detecting an air-in-line condition with respect to flow of liquid through tubing connected to an infusion pump, the method comprising:

providing an air-in-line sensor at a sensing location along the tubing, the air-in-line sensor generating a signal indicating whether a volume of fluid observed by the sensor at a given time is air or liquid;

operating the pump to deliver fluid at a therapy flow rate;

sampling the sensor signal as fluid flows past the sensor;

calculating a total volume of air observed by the sensor since the sensor last observed liquid;

operating the pump to deliver a bolus volume of fluid at a bolus flow rate greater than the therapy flow rate when the total volume of air exceeds a first threshold; and

detecting the air-in-line condition when the total volume of air exceeds a second threshold greater than the first threshold.

2. The method according to claim 1, further comprising the step of operating the pump to deliver fluid at a reduced flow rate less than the therapy flow rate after delivery of the bolus volume.

3. The method according to claim 2, wherein the pump is operated to deliver fluid at the reduced flow rate until an excess volume delivered relative to the therapy flow rate as a result of the delivery of the bolus volume is compensated for.

4. The method according to claim 3, further comprising the step of operating the pump to deliver fluid at the therapy flow rate after the excess volume has been compensated for.

5. The method according to claim 3, wherein the pump is operated according to equal time segments, and the reduced flow rate is applied over a plurality of the time segments subsequent to the time segment in which the bolus volume is delivered.

6. The method according to claim 5, wherein the plurality of time segments are consecutive time segments.

7. The method according to claim 6, wherein the plurality of consecutive time segments immediately follow the time segment during which the bolus volume was delivered.

8. The method according to claims 3, wherein the pump is operated according to equal time segments, and the reduced flow rate is applied only to a single time segment subsequent to the time segment in which the bolus volume is delivered.

9. The method according to claim 8, wherein single time segment immediately follows the time segment during which the bolus volume was delivered.

10. A method of clearing air microbubbles from an observation zone of an air-in-line sensor arranged to observe fluid flowing through tubing connected to an infusion pump, wherein the pump is programmed to deliver fluid at a therapy flow rate, the method comprising:

calculating a total volume of air observed by the sensor since the sensor last observed liquid; and

operating the pump to deliver a bolus volume of fluid at a bolus flow rate greater than the therapy flow rate when the total volume of air exceeds a predetermined threshold.

11. The method according to claim 10, wherein the infusion pump has a predetermined priming flow rate at which the pump is operated for priming the pump, and the bolus flow rate is substantially equal to the priming flow rate.

12. An infusion pump comprising:

a pumping mechanism operable to cause fluid flow through tubing connected to the pumping mechanism, the pumping mechanism including a motor and a motor controller for energizing the motor;

an air-in-line sensor arranged at a sensing location along the tubing to observe fluid flowing through the tubing, the air-in-line sensor generating a signal indicating whether a volume of fluid observed by the sensor at a given time is air or liquid;

a memory module; and

a microprocessor connected to the memory module, the pumping mechanism and the air-in-line sensor, wherein the microprocessor is programmable to command the pumping mechanism deliver fluid at a therapy flow rate;

wherein the memory module stores programming instructions causing the microprocessor to command the pumping mechanism to deliver a bolus volume of fluid at a bolus flow rate greater than the therapy flow rate in response to signals from the air-in-line sensor indicating an uninterrupted volume of air flowing through the tubing is greater than a predetermined first volume threshold.

13. The infusion pump according to claim 12, wherein the memory module stores programming instructions causing the microprocessor to register an air-in-line alarm condition in response to signals from the air-in-line sensor indicating an uninterrupted volume of air flowing through the tubing is greater than a predetermined second volume threshold greater than the first volume threshold.

14. The infusion pump according to claim 12, wherein the memory module stores programming instructions causing the microprocessor to evaluate signals from the air-in-line sensor to distinguish air from liquid containing microbubbles.

15. The infusion pump according to claim 12, wherein the memory module stores programming instructions causing the microprocessor to command the pumping mechanism to deliver fluid at a reduced flow rate less than the therapy flow rate after delivery of the bolus volume until an excess volume delivered relative to the therapy flow rate as a result of the delivery of the bolus volume is compensated for.

16. The infusion pump according to claim 15, wherein the reduced flow rate is a predetermined percentage of the therapy flow rate.

17. The infusion pump according to claim 16, wherein the predetermined percentage is 50%.

18. The infusion pump according to claim 15, wherein the memory module stores programming instructions causing the microprocessor to command the pumping mechanism to deliver fluid at the therapy flow rate after the excess volume has been compensated for.