CLOT RETRIEVAL DEVICE FOR REMOVING OCCLUSIVE CLOT FROM A BLOOD VESSEL

• US 20130345739A1
• Filed: 03/09/2012
• Published: 12/26/2013
• Est. Priority Date: 03/09/2011
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Gilvarry, Michael, Razavi, Mahmood K., Vale, David, Griffin, Patrick, Casey, Brendan, McNamara, Jason
• Granted Patent: US 9,301,769 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A clot retrieval device (9501) for removing occlusive clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration.

Claims

1. A clot retrieval device for removing occlusive clot from a blood vessel, the device comprising:

an inner elongate body having a collapsed delivery configuration and an expanded deployed configuration;

an outer elongate body at least partially overlying the inner elongate body;

the outer elongate body being expandable relative to the inner elongate body to a radial extent which is greater than the radial extent of the inner body in the deployed configuration.

2. A device as claimed in claim 1 comprising an elongate member having a proximal end and a distal end, the inner elongate body being connected to the elongate member adjacent to the distal end thereof, the inner elongate body being expandable relative to the elongate member.

3. A device as claimed in claim 2 wherein the outer elongate body is connected to the elongate member adjacent to the distal end thereof, the outer elongate body being expandable relative to the elongate member.

4. A device as claimed in claim 2 wherein the proximal end of the elongate member is adapted to extend exterior of the patient.

5. A device as claimed in claim 1 wherein, in the expanded configuration, the outer elongate body is radially spaced-apart from the inner elongate body to define therebetween an interior reception space and wherein the outer elongate body has at least one opening to receive a clot.

6. A device as claimed in claim 5 wherein the outer elongate body has an outer clot engaging region which is adapted, on engagement with clot, to urge clot towards the opening and into the interior reception space.

7. A device as claimed in claim 5 wherein the outer elongate body comprises a plurality of clot-receiving openings.

8. A device as claimed in claim 6 wherein the outer elongate body comprises a plurality of clot engaging regions.

9. A device as claimed in claim 1 wherein the inner elongate body is generally tubular.

10. A device as claimed in claim 1 wherein the inner elongate body comprises a non-circular cross-section.

11. A device as claimed in claim 1 wherein the outer surface of the inner elongate body has a greater surface roughness than the outer surface of the outer elongate body.

12. A device as claimed in claim 1 wherein the outer elongate body is generally tubular.

13. A device as claimed in claim 1 wherein the outer elongate body comprises at least two segments which are longitudinally spaced-apart.

14. A device as claimed in claim 13 at least two of said segments are connected by members comprising hinge elements.

15. A device as claimed in claim 13 wherein at least one segment is movable relative to another segment.

16. A device as claimed in claim 13 comprising linkages between the segments.

17. A device as claimed in claim 16 wherein the linkages are adapted for controlled movement between the segments.

18. A device as claimed in claim 1 comprising a distal capture net for trapping clot material.

19. A device as claimed in claim 18 wherein the capture net is connected to the outer elongate body or the inner elongate body.

20. A device as claimed in claim 18 wherein the capture net is mounted to or provided by a distal segment of either the outer elongate body and/or the inner elongate body.

21. A device as claimed in claim 18 wherein the capture net is mounted to a distal portion of the elongate member.

22. A device as claimed in claim 18 wherein the capture net comprises a plurality of radially inwardly projecting strut elements.

23. A device as claimed in claim 18 wherein the capture net comprises one or more fibers.

24. A device as claimed in claim 23 wherein the device comprises a plurality of fibre attachment eyelets to which said fibers are attached.

25. A device as claimed in claim 2 wherein the elongate member comprises an assembly of at least one elongate wire and at least one elongate tubular member.

26. A device as claimed in claim 25 wherein said elongate tubular member comprises a coil.

27. A device as claimed in claim 25 wherein the elongate wire is slidably movable relative to the elongate tubular member.

28. A device as claimed in claim 27 wherein movement of the elongate wire relative to the elongate tubular member effects movement of the outer elongate body relative to the inner elongate body and/or a distal capture net.

29. A device as claimed in claim 1 wherein the outer elongate body comprises a plurality of struts, each strut having a vessel contacting surface, an inner surface, a proximally facing surface and a distally facing surface, said proximally facing surface comprising at least one protrusion.

30. A device as claimed in claim 1 wherein the inner elongate body comprises a braided structure.

31. A device as claimed in claim 2 wherein the inner and/or outer elongate bodies are slidably attached to a distal region of the elongate member, such that movement of the elongate member can be effected without resultant movement of the inner and/or outer elongate bodies.

32. A device as claimed in claim 1 wherein the distal ends of the inner and outer elongate bodies are connected to one another.

33. A device as claimed in claim 32 wherein the distal ends of the inner and outer elongate bodies are connected to one another by a compliant element.

34. A device as claimed in claim 33 wherein the compliant element comprises a spring.

35. A clot retrieval device for removing occlusive clot from a blood vessel of a patient, the device comprising:

an elongate body which is expandable within a clot;

the elongate body having an outer clot engaging regions and openings into an interior space defined by the elongate body;

the clot engaging regions being adapted, on engagement with clot to urge the clot towards the openings and into the interior reception space.

36. A device as claimed in claim 35 further comprising an elongate member having a proximal end and a distal end, the distal end of said elongate member being connected to the elongate body, and the proximal end of said elongate member extending exterior of the patient.

37. A device as claimed in claim 35 wherein the elongate body is an outer elongate body and the device also comprises an inner elongate body which is at least partially overlayed by the outer elongate body, the outer elongate body being expandable relative to the inner elongate body to a radial extent which is greater than the radial extent of the inner body in the deployed configuration.

38. A device as claimed in claim 37 wherein the inner elongate body comprises a generally tubular structure of interconnected struts.

39. A device as claimed in claim 37 wherein the outer elongate body comprises two or more segments, at least some of the segments being connected to an adjacent segment by at least one flexible connecting element.

40. A device as claimed in claim 35 comprising a distal capture net.

41. A device as claimed in claim 40 wherein the capture net comprises a plurality of radially inwardly projecting strut elements.

42. A device as claimed in claim 40 wherein the capture net comprises one or more fibers.

43. A device as claimed in claim 42 wherein the device comprises a plurality of fibre attachment eyelets to which said fibers are attached.

44. A clot retrieval device for use in the treatment of a patient with an occluded blood vessel, the device comprising:

an elongate shaft and a clot engaging structure,

the clot engaging structure being connected to the distal end of the elongate shaft and the proximal end of the elongate shaft extending exterior of the patient,

the clot engaging structure comprising an outer wall and an inner reception space, said outer wall comprising a plurality of scaffolding sections and a plurality of inlet sections, said sections configured to urge clot into the inner reception space.

45. A device as claimed in claim 44 wherein the elongate body is an outer elongate body and the device also comprises an inner elongate body which is at least partially overlayed by the outer elongate body, the outer elongate body being expandable relative to the inner elongate body to a radial extent which is greater than the radial extent of the inner body in the deployed configuration.

46. A device as claimed in claim 45 wherein the inner elongate body comprises a generally tubular structure of interconnected struts.

47. A device as claimed in claim 45 wherein the outer elongate body comprises two or more segments, each segment connected to the adjacent segment by two or one flexible connecting elements.

48. A device as claimed in claim 44 comprising a distal capture net.

49. A device as claimed in claim 48 wherein the capture net comprises a plurality of radially inwardly projecting strut elements.

50. A device as claimed in claim 48 wherein the capture net comprises one or more fibers.

51. A device as claimed in claim 50 wherein the device comprises a plurality of fibre attachment eyelets to which said fibers are attached.