TRACKING BRAIN DEFORMATION DURING NEUROSURGERY

• US 20140003698A1
• Filed: 03/01/2012
• Published: 01/02/2014
• Est. Priority Date: 03/18/2011
• Status: Active Grant

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Babic, Drazenko, Ruijters, Danil Simon Anna
• Granted Patent: US 9,668,710 B2
• Time in Patent Office: Days
• US Class Current: 382/131
• CPC Class Codes: A61B 6/461 Displaying means of special interest
• CPC Class Codes: A61B 6/467 characterised by special input means
• CPC Class Codes: A61B 6/501 for diagnosis of the head, e.g. neuroimaging or craniography
• CPC Class Codes: A61B 6/5217 extracting a diagnostic or physiological parameter from medical diagnostic data
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61B 6/5247 combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/30016 Brain
• CPC Class Codes: G06T 2207/30101 Blood vessel; Artery; Vein; Vascular
• CPC Class Codes: G06T 7/33 using feature-based methods

Abstract

The present invention relates to the determination of brain deformation. The invention relates in particular to a device for tracking brain deformation, an imaging system for tracking brain deformation, a method for tracking brain deformation, a method of operating a device for tracking brain deformation, as well as to a computer program element and a computer readable medium. For providing enhanced information about the brain deformation, a first 3D representation (112) of a cerebrovascular vessel structure of a region of interest of an object is provided (110) and (114) a second 3D representation (116) of the cerebrovascular vessel structure. Then, at least a part of the first 3D representation is elastically three dimensionally registered (118) with at least a part of the second 3D representation. A deformation field (122) of the cerebrovascular vessel structure is determined (120) based on the elastic registration. The determined vessel deformation is applied (124) to a brain structure representation to determine a deformation (126) of the cerebral structure. For example, planning data (130) for an intervention of the cerebral structure is provided (132) and the determined deformation of the cerebral structure is applied (134) to the planning data to generate deformation adjusted planning data (136).

Claims

1. A device for tracking brain deformation, comprising:

a processing unit; and

an interface unit;

wherein the interface unit is adapted to provide a first 3D representation of a cerebrovascular vessel structure of a region of interest of an object to the processing unit; and

to provide a second 3D representation of the cerebrovascular vessel structure to the processing unit; and

wherein the processing unit has a register unit adapted to elastically three-dimensionally register at least a part of the first 3D representation with at least a part of the second 3D representation;

wherein the processing unit has a determination unit adapted to determine a deformation field of the cerebrovascular vessel structure based on the elastic registration; and

wherein the processing unit has an application unit adapted to apply the determined vessel deformation to a brain structure representation to determine a deformation of the cerebral structure;

wherein at least the second 3D representation is based on X-ray image data.

2. Device according to claim 1, wherein the application unit is adapted to apply the determined deformation of the cerebral structure to planning data for an intervention of the cerebral structure to generate deformation adjusted planning data.

3. Device according to claim 1, wherein the processing unit comprises an extrapolation unit adapted to extrapolate the determined vessel deformation to the brain structure representation;

wherein the brain structure representation comprises a vessel structure and a lobe structure comprising a number of convolutions in which the vessels are arranged; and

wherein the application unit is adapted to apply the deformation to the lobes only.

4. Device according to claim 1, wherein the interface unit is adapted to provide at least one further 3D representation of a further cerebrovascular structure;

wherein the further cerebrovascular structure is based on a morphological brain scan and/or a functional brain scan; and

wherein the application unit is adapted to apply the determined vessel deformation to the further cerebrovascular structure.

5. Device according to claim 1, wherein the processing unit comprises a generation unit adapted to generate a deformation indicator from the deformation of the cerebral structure;

and

wherein a display unit is provided adapted to display the deformation indicator to a user.

6. Device according to claim 1, wherein the interface unit is adapted to provide the deformation adjusted planning data to an external navigation system.

7. An imaging system for tracking brain deformation, comprising:

a device according to claim 1; and

an image acquisition device;

wherein the image acquisition device is adapted to acquire 3D image data for the first and second representation; and

wherein the processing unit comprises a 3D image data generation unit adapted to generate the first and second representation from the 3D image data;

wherein the image acquisition device is adapted to acquire the second image data in a contactless manner;

wherein the image acquisition device is an X-ray image acquisition device adapted to acquire 3D X-ray image data.

8. Imaging system according to claim 7, wherein the image acquisition device is adapted to acquire the data for the first and the second 3D representations with the same imaging modality;

and

wherein the 3D image data generation unit is adapted to generate the data for the first and the second 3D representations with the same processing steps.

9. (canceled)

10. A method for tracking brain deformation, comprising the following steps:

a) providing a first 3D representation of a cerebrovascular vessel structure of a region of interest of an object;

b) providing a second 3D representation of the cerebrovascular vessel structure;

wherein at least the second 3D representation is based on X-ray image data;

c) elastically three-dimensionally registering at least a part of the first 3D representation with at least a part of the second 3D representation;

d) determining a deformation field of the cerebrovascular vessel structure based on the elastic registration; and

e) applying the determined vessel deformation to a brain structure representation to determine a deformation of the cerebral structure.

11. Method according to claim 10, wherein planning data for an intervention of the cerebral structure is provided and wherein, following step e), a step f) is provided in which the determined deformation of the cerebral structure is applied to the planning data to generate deformation adjusted planning data.

13. Computer program element for controlling an apparatus, which, when being executed by a processing unit, is adapted to perform the method steps of claim 10.

14. Computer readable medium having stored the program element of claim 13.

12. A method of operating a device for tracking brain deformation,

wherein a processing unit provides a first 3D representation of a cerebrovascular vessel structure of a region of interest of an object;

wherein the processing unit provides a second 3D representation of the cerebrovascular vessel structure;

wherein at least the second 3D representation is based on X-ray image data;

wherein the processing unit elastically three-dimensionally registers at least a part of the first 3D representation with at least a part of the second 3D representation;

wherein the processing unit determines a deformation field of the cerebrovascular vessel structure based on the elastic registration; and

wherein the processing unit applies the determined vessel deformation to a brain structure representation to determine a deformation of the cerebral structure.