CYCLOPROPYLAMINES AS LSD1 INHIBITORS
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Abstract
This invention relates to the use of cyclopropylamine derivatives for the modulation, notably the inhibition of the activity of Lysine-specific demethylase 1 (LSD1). Suitably, the present invention relates to the use of cyclopropylamines in the treatment of cancer.
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Citations
26 Claims
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1-22. -22. (canceled)
- 23. A compound which is 4-((4((((1R,2S)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)methyl)benzoic acid, represented by the formula:
- 24. A compound which is 4-((4((((1R,2S)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)methyl)benzoic acid, represented by the formula:
Specification