APPARATUS AND METHOD FOR CHANNEL COUNT REDUCTION IN SOLID-STATE-BASED POSITRON EMISSION TOMOGRAPHY

• US 20140021354A1
• Filed: 07/18/2012
• Published: 01/23/2014
• Est. Priority Date: 07/18/2012
• Status: Active Grant

• Current Assignee: Toshiba Medical Systems Corporation (Canon Inc.)
• Original Assignee: Toshiba Medical Systems Corporation (Canon Inc.), Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: GAGNON, Daniel, Junnarkar, Sachin S.
• Granted Patent: US 9,176,240 B2
• Time in Patent Office: Days
• US Class Current: 250/362
• CPC Class Codes: G01T 1/1647 Processing of scintigraphic data not related to a particular imaging system G01T1/2992
• CPC Class Codes: G01T 1/208 Circuits specially adapted for scintillation detectors, e.g. for the photo-multiplier section

Abstract

An apparatus and method for channel count reduction in solid-state-based positron emission tomography that multiplexes read-outs from photo-detectors using a sum delay circuit, including a sum channel and a delay-sum channel. The sum channel sums signals from sensors in an array and is digitized to extract the timing and energy information. A delay-sum channel includes a discrete delay line that introduces a known delay after each sensor, creating a time signature for the sensor, followed by a summing circuit that adds the delayed signals. The delay-sum channel is digitized using a high speed counters to extract location information. Start and Stop signals for the counter are derived when the sum channel output and the delay-sum channel output cross a pulse ID threshold, respectively. The pulse ID threshold is chosen to minimize the Compton scatter and not clip the photo-peak events.

Claims

1. A data acquisition device for a gamma ray detector, comprising:

a summing circuit configured to sum a plurality of electrical signals from a corresponding plurality of sensors coupled to an array of scintillation crystals to generate a first signal, the plurality of sensors converting received light into the plurality of electrical signals, wherein the light is generated by a crystal of interaction in response to incident gamma rays generated by an annihilation event;

a delay summing circuit configured to selectively delay and sum the plurality of electrical signals to generate a second signal;

a first circuit configured to receive the first signal and to determine an energy and an event time of the first signal; and

a second circuit configured to receive the first signal and the second signal and to determine, when the first signal exceeds a predetermined threshold, which sensor of the plurality of sensors corresponds to a location of the crystal of interaction.

2. The data acquisition device of claim 1, wherein the delay summing circuit comprises:

at least one summer and at least one delay element so that the second signal is a sum of each signal of the plurality of electrical signals delayed by a different amount of time.

3. The data acquisition device of claim 1, wherein the plurality of sensors form a row, a column, or a block of sensors within a larger array of sensors.

4. The data acquisition device of claim 1, wherein the second circuit comprises:

a pulse ID threshold generator configured to generate the predetermined threshold;

a first comparator configured to compare the first signal with the predetermined threshold, and to generate a start signal when the first signal exceeds the predetermined threshold;

a second comparator configured to compare the second signal with the predetermined threshold, and to generate a stop signal when the second signal exceeds the predetermined threshold; and

a counter configured to receive the start and stop signals, to start counting in response to receiving the start signal, and to stop counting in response to receiving the stop signal.

5. The data acquisition device of claim 1, further comprising:

a first pre-amplifier/shaper circuit configured to pre-amplify and shape the first signal; and

a second pre-amplifier/shaper circuit configured to pre-amplify and shape the second signal.

6. The data acquisition device of claim 1, wherein the first circuit includes an analog-to-digital converter that digitizes the first signal.

7. The data acquisition device of claim 4, wherein the pulse ID threshold generator includes a digital-to-analog converter.

8. The data acquisition device of claim 1, wherein each sensor of the plurality of sensors is substantially a same size as each scintillation crystal in the array of scintillation crystals, so that each sensor covers a corresponding scintillation crystal.

9. A gamma ray detector, comprising:

an array of scintillation crystals;

an array of sensors; and

a plurality of data acquisition devices, each data acquisition device including

a summing circuit configured to sum a plurality of electrical signals from a corresponding plurality of sensors coupled to the array of scintillation crystals to generate a first signal, the plurality of sensors converting received light into the plurality of electrical signals, wherein the light is generated by a crystal of interaction in response to incident gamma rays generated by an annihilation event;

a delay summing circuit configured to selectively delay and sum the plurality of electrical signals to generate a second signal;

a first circuit configured to receive the first signal and to determine an energy and an event time of the first signal; and

a second circuit configured to receive the first signal and the second signal and to determine, when the first signal exceeds a predetermined threshold, which sensor of the plurality of sensors corresponds to a location of the crystal of interaction.

10. The gamma ray detector of claim 9, wherein the delay summing circuit comprises:

at least one summer and at least one delay element so that the second signal is a sum of each signal of the plurality of electrical signals delayed by a different amount of time.

11. The gamma ray detector of claim 9, wherein the plurality of sensors form a row, a column, or a block of sensors within a larger array of sensors.

12. The gamma ray detector of claim 9, wherein the second circuit comprises:

a pulse ID threshold generator configured to generate the predetermined threshold;

a first comparator configured to compare the first signal with the predetermined threshold, and to generate a start signal when the first signal exceeds the predetermined threshold;

a second comparator configured to compare the second signal with the predetermined threshold, and to generate a stop signal when the second signal exceeds the predetermined threshold; and

a counter configured to receive the start and stop signals, to start counting in response to receiving the start signal, and to stop counting in response to receiving the stop signal.

13. The gamma ray detector of claim 9, further comprising:

a first pre-amplifier/shaper circuit configured to pre-amplify and shape the first signal; and

a second pre-amplifier/shaper circuit configured to pre-amplify and shape the second signal.

14. The gamma ray detector of claim 9, wherein the first circuit includes an analog-to-digital converter that digitizes the first signal.

15. The gamma ray detector of claim 12, wherein the pulse ID threshold generator includes a digital-to-analog converter.

16. The gamma ray detector of claim 9, wherein each sensor of the plurality of sensors is substantially a same size as each scintillation crystal in the array of scintillation crystals, so that each sensor covers a corresponding scintillation crystal.

17. A gamma ray detection method, comprising:

generating a first signal by summing a plurality of electrical signals from a corresponding plurality of sensors coupled to an array of scintillation crystals, the plurality of sensors converting received light into the plurality of electrical signals, wherein the light is generated by a crystal of interaction in response to incident gamma rays generated by an annihilation event;

generating a second signal by selectively delaying and summing the plurality of electrical signals;

determining an energy and an event time of the first signal; and

determining, based on the second signal, which sensor of the plurality of sensors corresponds to a location of the crystal of interaction, when the first signal exceeds a predetermined threshold.

18. The gamma ray detection method of claim 17, wherein the plurality of sensors form a row, a column, or a block of sensors within a larger array of sensors.

19. The gamma ray detection method of claim 17, further comprising:

generating the predetermined threshold;

comparing the first signal with the predetermined threshold;

generating a start signal when the first signal exceeds the predetermined threshold;

comparing the second signal with the predetermined threshold;

generating a stop signal when the second signal exceeds the predetermined threshold;

starting counting in response to the generation of the start signal; and

stopping counting in response to the generation of the stop signal.

20. The gamma ray detection method of claim 17, further comprising:

pre-amplifying and shaping the first signal and the second signal.

21. The gamma ray detection method of claim 17, further comprising:

digitizing the first signal using an analog-to-digital converter.

22. The gamma ray detection method of claim 17, wherein each sensor of the plurality of sensors is substantially a same size as each scintillation crystal in the array of scintillation crystals, so that each sensor covers a corresponding scintillation crystal.