CORRELATIVE DRIFT CORRECTION
First Claim
Patent Images
1. A correlative drift correction system, comprising:
- a sample stage configured to support a sample and a cover slip;
an infrared light source configured to emit infrared light to be reflected at the cover slip;
an optical sensor for detecting the reflected infrared light;
a drift detection module configured to detect drift of the sample using reflected infrared light data from the optical sensor; and
a drift correction module configured to determine a drift correction to apply to image data associated with the sample.
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Abstract
A correlative drift correction system can include a sample stage for supporting a sample and a cover slip. The system can include an infrared light source for emitting infrared light to be reflected at the cover slip and an optical sensor for detecting the reflected infrared light. The system can detect drift of the sample using reflected infrared light data from the optical sensor and can determine a drift correction to apply to image data of the sample.
15 Citations
20 Claims
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1. A correlative drift correction system, comprising:
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a sample stage configured to support a sample and a cover slip; an infrared light source configured to emit infrared light to be reflected at the cover slip; an optical sensor for detecting the reflected infrared light; a drift detection module configured to detect drift of the sample using reflected infrared light data from the optical sensor; and a drift correction module configured to determine a drift correction to apply to image data associated with the sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A correlative drift correction system, comprising:
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a sample stage configured to support a sample and a cover slip; an optical observation system for use in observing the sample on the sample stage; a visible light source configured to illuminate the sample with visible light for observation; an infrared light source configured emit infrared light to be reflected at the cover slip; a first optical sensor for detecting reflected infrared light data; a second optical sensor for capturing image data of the sample by detecting the visible light; a drift detection module configured to detect drift of the sample using the reflected infrared light data; and a drift correction module configured to determine a drift correction to apply to the image data. - View Dependent Claims (11, 12, 13)
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14. A method for correlative drift correction, comprising:
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directing infrared light from an infrared light source toward a sample stage supporting a sample and a cover slip; detecting the infrared light reflected at the cover slip using an optical sensor; directing visible light from a visible light source toward the sample stage; capturing visible light image data of the sample; detecting drift of the sample using reflected infrared light data from the optical sensor; and applying a drift correction to the visible light image data based on the drift. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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Specification