CANCER GENE THERAPY USING NUCLEIC ACIDS ENCODING US28 AND G-PROTEIN
First Claim
Patent Images
1. A polypeptide which is encoded by a nucleotide sequence depicted in SEQ ID NO:
- 8 or by a derivative thereof.
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Accused Products
Abstract
The invention relates to the gene therapeutic treatment of cancer using co-expressed nucleic acids encoding US28 and a G-protein. e.g. GNA-13, or functional fragments thereof, or using nucleic acids encoding fusion polypeptides of US28 and a G-protein or functional fragments thereof. The pharmaceutical compositions according to the invention are used in the treatment of cancer patients to induce apoptosis in tumor cells.
10 Citations
12 Claims
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1. A polypeptide which is encoded by a nucleotide sequence depicted in SEQ ID NO:
- 8 or by a derivative thereof.
- View Dependent Claims (2, 3, 8, 12)
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4-7. -7. (canceled)
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9-11. -11. (canceled)
Specification