APPARATUS, SYSTEMS, AND METHODS FOR TISSUE OXIMETRY AND PERFUSION IMAGING
First Claim
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1. An apparatus for monitoring perfusion oxygenation of a target tissue region of a patient, comprising:
- a scanner comprising;
a planar sensor array;
the sensor array configured to be positioned in contact with a surface of the target tissue region;
the sensor array comprising one or more LED'"'"'s configured to emit light into the target tissue region at a wavelength keyed for hemoglobin;
the sensor array comprising one or more photodiodes configured to detect light reflected from the LED'"'"'s; and
a data acquisition controller coupled to the one or more LED'"'"'s and to the one or more photodiodes for controlling the emission and reception of light from the sensor array to obtain perfusion oxygenation data associated with the target tissue region.
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Abstract
A compact perfusion scanner and method of characterizing tissue health status are disclosed that incorporate pressure sensing components in conjunction with the optical sensors to monitor the level of applied pressure on target tissue for precise skin/tissue blood perfusion measurements and oximetry. The systems and methods allow perfusion imaging and perfusion mapping (geometric and temporal), signal processing and pattern recognition, noise cancelling and data fusion of perfusion data, scanner position and pressure readings.
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Citations
31 Claims
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1. An apparatus for monitoring perfusion oxygenation of a target tissue region of a patient, comprising:
a scanner comprising; a planar sensor array; the sensor array configured to be positioned in contact with a surface of the target tissue region; the sensor array comprising one or more LED'"'"'s configured to emit light into the target tissue region at a wavelength keyed for hemoglobin; the sensor array comprising one or more photodiodes configured to detect light reflected from the LED'"'"'s; and a data acquisition controller coupled to the one or more LED'"'"'s and to the one or more photodiodes for controlling the emission and reception of light from the sensor array to obtain perfusion oxygenation data associated with the target tissue region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A system for monitoring perfusion oxygenation of a target tissue region of a patient, comprising:
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(a) a scanner comprising; a planar sensor array; the sensor array configured to be positioned in contact with a surface of the target tissue region; the sensor array comprising one or more light sources configured to emit light into the target tissue region at a wavelength keyed for hemoglobin; the sensor array comprising one or more sensors configured to detect light reflected from the light sources; a pressure sensor coupled to the sensor array; the pressure sensor configured to obtain pressure readings of the sensor array'"'"'s contact with a surface of the target tissue region; and (b) a data acquisition controller coupled to the one or more sensors and for controlling the emission and reception of light from the sensor array to obtain perfusion oxygenation data associated with the target tissue; and (c) a processing module coupled to the data acquisition controller; (d) the processing module configured to control sampling of the pressure sensor and sensor array for simultaneous acquisition of perfusion oxygenation data and pressure sensor data to ensure proper contact of the scanner with the surface of the target tissue region. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method for performing real-time monitoring of perfusion oxygenation of a target tissue region of a patient, comprising:
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positioning a sensor array in contact with a surface of the target tissue region; emitting light from lights sources in the sensor array into the target tissue region at a wavelength keyed for hemoglobin; receiving light reflected from the light sources; obtaining pressure data associated with the sensor array'"'"'s contact with a surface of the target tissue region; obtaining perfusion oxygenation data associated with the target tissue region; and sampling the perfusion oxygenation data and pressure data to ensure proper contact of the sensor array with the surface of the target tissue region. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification