MRI-GUIDED CATHETERS

• US 20140024909A1
• Filed: 02/24/2012
• Published: 01/23/2014
• Est. Priority Date: 02/24/2011
• Status: Abandoned Application

• Current Assignee: MRI Interventions, Inc. (Clearpoint Neuro, Inc.)
• Original Assignee: MRI Interventions, Inc. (Clearpoint Neuro, Inc.)
• Inventors: Vij, Kamal, Karmarkar, Parag V., Piferi, Peter, Pandey, Rajesh
• Application Number:
  US13/984,437
• Publication Number:
  US 20140024909A1
• Time in Patent Office: Days
• US Class Current: 600/373
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 18/06 caused by chemical reaction , e.g. moxaburners
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: A61B 5/0036 including treatment, e.g., using an implantable medical device, ablating, ventilating
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/062 using magnetic field
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61M 25/0127 Magnetic means; Magnetic markers
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

An MRI-compatible catheter reduces localized heating due to MR scanner-induced currents and includes a shaft having opposite distal and proximal end portions. One or more RF tracking coils are positioned adjacent the distal end portion and each includes a conductive lead that electrically connects the RF tracking coil to an MRI scanner. Each lead includes a series of back and forth segments along its length. The catheter includes one or more sensing electrodes at the shaft distal end portion, each electrically connected to a resistor having high impedance. A sheath surrounds a portion of the elongated shaft and includes at least one RF shield coaxially disposed therewithin. Each RF shield includes elongated inner and outer conductors and an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors. The inner and outer conductors are electrically connected at one end and electrically isolated at an opposite end.

Claims

1. An MRI-compatible catheter, comprising:

an elongated flexible shaft having a distal end portion, and an opposite proximal end portion;

a handle attached to the proximal end portion, wherein the handle includes an electrical connector interface configured to be in electrical communication with an MRI scanner; and

at least one RF tracking coil positioned adjacent the distal end portion, wherein the at least one tracking coil includes a conductive lead extending between the at least one RF tracking coil and the electrical connector interface and configured to electrically connect the at least one tracking coil to the MRI scanner, and wherein the conductive lead includes a series of pre-formed back and forth segments along its length; and

at least one sensing electrode at the shaft distal end portion.

2. The catheter of claim 1, wherein the conductive lead is a coaxial cable.

3. The catheter of claim 2, wherein the coaxial cable comprises a self-resonant cable trap, and wherein the coaxial cable comprises a self-resonant cable trap.

6. The catheter of claim 1, further comprising an ablation tip at the shaft distal end portion, and wherein an RF conductor extends longitudinally within the shaft to the electrical connector interface at the handle and that connects the ablation tip to an RF generator.

7. The catheter of claim 6, further comprising a thermocouple at the shaft distal end portion.

8. The catheter of claim 6, further comprising at least one fluid exit port at the shaft distal end portion, wherein the at least one fluid exit port is in fluid communication with an irrigation lumen that extends longitudinally through the catheter shaft lumen from the at least one exit port to the proximal end portion of the catheter shaft, wherein the irrigation lumen is in fluid communication with a fluid/solution source at the proximal end portion of the catheter shaft.

9. The catheter of claim 6, wherein the RF conductor includes a series of pre-formed back and forth segments along its length.

11. The catheter of claim 1, wherein the at least one RF tracking coil comprises a tuning circuit configured to stabilize a tracking signal generated by the at least one RF tracking coil.

13. The catheter of claim 1, further comprising a sheath surrounding at least a portion of the elongated shaft, wherein the sheath includes at least one RF shield coaxially disposed therewithin, the at least one RF shield comprising:

elongated inner and outer conductors, each having respective opposite first and second end portions, wherein the inner and outer conductors comprise conductive foil, conductive braid, or a film with a conductive surface; and

an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors and surrounding the inner conductor, wherein only the respective first end portions of the inner and outer conductors are electrically connected, and wherein the second end portions are electrically isolated.

16. The catheter of claim 1, further comprising at least one RF shield coaxially disposed within the flexible shaft, the at least one RF shield comprising:

elongated inner and outer conductors, each having respective opposite first and second end portions, wherein the inner and outer conductors comprise conductive foil, conductive braid, or a film with a conductive surface; and

an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors and surrounding the inner conductor, wherein only the respective first end portions of the inner and outer conductors are electrically connected, and wherein the second end portions are electrically isolated.

4-5. -5. (canceled)

10. (canceled)

12. (canceled)

14-15. -15. (canceled)

17-18. -18. (canceled)

19. An MRI-compatible catheter, comprising:

an elongated flexible shaft having a distal end portion, and an opposite proximal end portion;

a handle attached to the proximal end portion, wherein the handle includes an electrical connector interface configured to be in electrical communication with an MRI scanner;

at least one RF tracking coil positioned adjacent the distal end portion, wherein the at least one tracking coil includes a conductive lead extending between the at least one RF tracking coil and the electrical connector interface and configured to electrically connect the at least one tracking coil to the MRI scanner;

at least one sensing electrode at the shaft distal end portion, wherein the at least one sensing electrode is electrically connected to a resistor having an impedance of at least about 5,000 ohms; and

a sheath surrounding at least a portion of the elongated shaft, wherein the sheath includes at least one RF shield coaxially disposed therewithin, the at least one RF shield comprising;

elongated inner and outer conductors, each having respective opposite first and second end portions; and

an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors and surrounding the inner conductor, wherein only the respective first end portions of the inner and outer conductors are electrically connected, and wherein the second end portions are electrically isolated.

20. The catheter of claim 19, wherein the conductive lead is a coaxial cable that comprises a series of pre-formed back and forth segments along its length.

22. The catheter of claim 20, wherein the coaxial cable comprises a self-resonant cable trap, wherein the self-resonant cable trap comprises a 60-turn inductor.

25. The catheter of claim 19, further comprising an ablation tip at the shaft distal end portion, and wherein an RF conductor extends longitudinally within the shaft to the electrical connector interface at the handle and that connects the ablation tip to an RF generator.

26. The catheter of claim 25, wherein the RF conductor includes a series of pre-formed back and forth segments along its length.

27. The catheter of claim 19, wherein the inner and outer conductors comprise conductive foil, conductive braid, or a film with a conductive surface.

29. The catheter of claim 19, wherein the at least one RF tracking coil comprises a tuning circuit configured to stabilize a tracking signal generated by the at least one RF tracking coil.

21. (canceled)

23-24. -24. (canceled)

28. (canceled)

30. (canceled)

31. An MRI-compatible ablation catheter, comprising:

an elongated flexible shaft having a distal end portion, and an opposite proximal end portion;

a handle attached to the proximal end portion, wherein the handle includes an electrical connector interface configured to be in electrical communication with an MRI scanner and an ablation energy source;

an ablation tip at the shaft distal end portion;

an RF conductor extending longitudinally within the shaft to the electrical connector interface at the handle that connects the ablation tip to an RF generator, wherein the RF conductor includes a series of pre-formed back and forth segments along its length;

at least one RF tracking coil positioned adjacent the distal end portion, wherein the at least one tracking coil includes a conductive lead extending between the at least one RF tracking coil and the electrical connector interface and configured to electrically connect the at least one tracking coil to the MRI scanner, and wherein the conductive lead includes a series of pre-formed back and forth segments along its length; and

a sheath surrounding at least a portion of the elongated shaft, wherein the sheath includes at least one RF shield coaxially disposed therewithin.

32. The ablation catheter of claim 31, wherein the conductive lead is a coaxial cable.

33. The ablation catheter of claim 32, wherein the coaxial cable comprises a self-resonant cable trap, wherein the self-resonant cable trap comprises a 60-turn inductor.

36. The ablation catheter of claim 31, wherein the at least one RF tracking coil comprises a tuning circuit configured to stabilize a tracking signal generated by the at least one RF tracking coil.

38. The ablation catheter of claim 31, wherein the at least one RF shield comprises:

elongated inner and outer conductors, each having respective opposite first and second end portions, wherein the inner and outer conductors comprise conductive foil, conductive braid, or a film with a conductive surface; and

an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors and surrounding the inner conductor, wherein only the respective first end portions of the inner and outer conductors are electrically connected, and wherein the second end portions are electrically isolated.

41. The ablation catheter of claim 31, further comprising at least one sensing electrode at the shaft distal end portion, wherein the at least one sensing electrode is electrically connected to a resistor having an impedance of at least about 5,000 ohms;

a thermocouple at the shaft distal end portion; and

at least one fluid exit port at the shaft distal end portion, wherein the at least one fluid exit port is in fluid communication with an irrigation lumen that extends longitudinally through the catheter shaft lumen from the at least one exit port to the proximal end portion of the catheter shaft, wherein the irrigation lumen is in fluid communication with a fluid/solution source at the proximal end portion of the catheter shaft.

34-35. -35. (canceled)

37. (canceled)

39-40. -40. (canceled)

42-43. -43. (canceled)