INFUSION PUMP ASSEMBLY

• US 20140031743A1
• Filed: 07/19/2013
• Published: 01/30/2014
• Est. Priority Date: 12/31/2007
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Kamen, Dean, Kerwin, John Matthew, Murphy, Colin Holmes
• Granted Patent: US 10,912,882 B2
• Time in Patent Office: Days
• US Class Current: 604/67
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 2205/8237 Charging means
• CPC Class Codes: A61M 2209/086 Docking stations
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/16809 by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: A61M 5/16886 for measuring fluid flow rate, i.e. flowmeters
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence

Abstract

A wearable infusion pump assembly including a reservoir for receiving an infusible fluid, and a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set. The fluid delivery system includes a volume sensor assembly configured to receive a quantity of the infusible fluid from the reservoir. The volume sensor assembly includes an acoustically contiguous region having a volume that varies based upon the quantity of infusible fluid received from the reservoir, and an acoustic energy emitter configured to provide acoustic energy at a plurality of frequencies to excite a gas included within the acoustically contiguous region.

Claims

1. A wearable infusion pump assembly comprising:

a reservoir for receiving an infusible fluid; and

a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set, wherein the fluid delivery system includes;

a volume sensor assembly configured to receive a quantity of the infusible fluid from the reservoir, the volume sensor assembly including;

an acoustically contiguous region having a volume that varies based upon the quantity of infusible fluid received from the reservoir, and

an acoustic energy emitter configured to provide acoustic energy at a plurality of frequencies to excite a gas included within the acoustically contiguous region.

2. The wearable infusion pump assembly of claim 1 wherein the volume sensor assembly further includes:

a first acoustic energy receptor for receiving at least a portion of the acoustic energy provided by the acoustic energy emitter and defining an acoustic response for each of the plurality of frequencies; and

a second acoustic energy receptor for receiving at least a portion of the acoustic energy provided by the acoustic energy emitter and defining an acoustic reference for each of the plurality of frequencies.

3. The wearable infusion pump assembly of claim 2 wherein the acoustically contiguous region includes:

a variable volume chamber having a volume that varies based upon the quantity of infusible fluid received from the reservoir,

at least one fixed volume chamber having a volume that is constant regardless of the quantity of infusible fluid received from the reservoir, and

at least one acoustic port for acoustically coupling the variable volume chamber to the at least one fixed volume chamber.

4. The wearable infusion pump assembly of claim 3 wherein:

the first acoustic energy receptor is an invariable microphone positioned proximate the variable volume chamber; and

the second acoustic energy receptor is a reference microphone positioned proximate the at least one fixed volume chamber.

5. The wearable infusion pump assembly of claim 2 further comprising:

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

determining a phase relationship between the acoustic response and the reference for each of the plurality of frequencies.

6. The wearable infusion pump assembly of claim 5 wherein the computer readable medium further includes instructions for:

calculating a change of volume characteristic based, at least in part, upon the phase relationship between the acoustic response and the acoustic reference for each of the plurality of frequencies.

7. The wearable infusion pump assembly of claim 6 further comprising:

a disposable housing assembly including the reservoir and a first portion of the fluid delivery system; and

a reusable housing assembly including a second portion of the fluid delivery system.

8. The wearable infusion pump assembly of claim 7 wherein a first portion of a pump assembly is positioned within the disposable housing assembly, and a second portion of the pump assembly is positioned within the reusable housing assembly, wherein the pump assembly is configured to extract the quantity of the infusible fluid from the reservoir and provide the quantity of the infusible fluid to the volume sensor assembly.

9. The wearable infusion pump assembly of claim 8 wherein a first portion of a first valve assembly is positioned within the disposable housing assembly, and a second portion of the first valve assembly is positioned within the reusable housing assembly, wherein the first valve assembly is configured to selectively isolate the pump assembly from the reservoir.

10. The wearable infusion pump assembly of claim 9 wherein a first portion of a second valve assembly is positioned within the disposable housing assembly, and a second portion of the second valve assembly is positioned within the reusable housing assembly, wherein the second valve assembly is configured to selectively isolate the volume sensor assembly from the external infusion set.

11. A wearable infusion pump assembly comprising:

a reservoir for receiving an infusible fluid;

a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set, wherein the fluid delivery system includes a volume sensor assembly configured to receive a quantity of the infusible fluid from the reservoir;

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

calculating a first volume characteristic prior to providing the quantity of the infusible fluid to the external infusion set,

calculating a second volume characteristic subsequent to providing the quantity of the infusible fluid to the external infusion set, and

determining whether an occlusion condition is occurring.

12. The wearable infusion pump assembly of claim 11 wherein the instructions for determining whether an occlusion condition is occurring include instructions for:

calculating a differential volume from the first volume characteristic and the second volume characteristic; and

analyzing the differential volume to determine whether an occlusion condition is occurring.

13. A wearable infusion pump assembly comprising:

a reservoir for receiving an infusible fluid;

a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set, wherein the fluid delivery system includes a volume sensor assembly configured to receive a quantity of the infusible fluid from the reservoir;

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

determining a quantity of the infusible fluid delivered to a user via the external infusion set;

comparing the quantity of the infusible fluid delivered to a delivery target quantity to determine a differential quantity; and

adjusting a subsequently delivered quantity of the infusible fluid to offset the differential quantity.

14. The wearable infusion pump assembly of claim 13 wherein the differential quantity represents an over delivery and the subsequently delivered quantity of the infusible fluid is decreased by the differential quantity.

15. The wearable infusion pump assembly of claim 13 wherein the differential quantity represents an under delivery and the subsequently delivered quantity of the infusible fluid is increased by the differential quantity.

16. A wearable infusion pump assembly comprising:

a reusable housing assembly;

a disposable housing assembly including a reservoir for receiving an infusible fluid;

a releasable engagement assembly configured to allow the reusable housing assembly to releasably engage the disposable housing assembly;

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

executing one or more hierarchical state machines to effectuate the delivery of one or more bolus infusion events.

17. A wearable infusion pump assembly comprising:

a reusable housing assembly;

a disposable housing assembly including a reservoir for receiving an infusible fluid;

a releasable engagement assembly configured to allow the reusable housing assembly to releasably engage the disposable housing assembly;

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

executing one or more hierarchical state machines to effectuate the delivery of one or more basal infusion events.

18. A wearable infusion pump assembly comprising:

a reusable housing assembly;

a disposable housing assembly including a reservoir for receiving an infusible fluid;

a releasable engagement assembly configured to allow the reusable housing assembly to releasably engage the disposable housing assembly;

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

executing one or more hierarchical state machines to effectuate the execution of one or more occlusion detection events.

19. A wearable infusion pump assembly comprising:

a reusable housing assembly;

a disposable housing assembly including a reservoir for receiving an infusible fluid;

a releasable engagement assembly configured to allow the reusable housing assembly to releasably engage the disposable housing assembly;

at least one processor; and

a computer readable medium coupled to the at least one processor, the computer readable medium including a plurality of instructions stored thereon which, when executed by the at least one processor, cause the at least one processor to perform operations comprising;

executing one or more hierarchical state machines to effectuate the execution of one or more pairing events.

20. A wearable infusion pump assembly comprising:

a reusable housing assembly;

a disposable housing assembly including a reservoir for receiving an infusible fluid;

a releasable engagement assembly configured to allow the reusable housing assembly to releasably engage the disposable housing assembly; and

a filling station including an infusible fluid supply, the filling station configured to releasably fluidly couple the reservoir and effectuate the delivery of the infusible fluid from the filling station to the reservoir.