IMMUNOGENIC COMPOSITION FOR IMMUNE SYSTEM MODULATION AND USE THEREOF, METHOD FOR TREATING AND PREVENTING DISEASES, METHOD FOR INDUCING CELL REGENERATION AND METHOD FOR RESTORING IMMUNE RESPONSE
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Abstract
The present invention relates to immunogenic compositions for modulating the immune system, comprising a therapeutically effective quantity of two or more immuno-active antigenic agents with pathogen-associated molecular patterns (PAMPs) and/or danger-associated molecular patterns (DAMPs) and one or more physiologically acceptable carriers, excipients, diluents or solvents. The immunogenic compositions according to the present invention are used for producing medicaments for preventing and/or treating, and for preventing and/or treating infectious diseases, auto-immune diseases, allergic diseases, inflammation, arthritis, inflammatory diseases, transplant rejection, affections caused by vascular disorders, diseases caused by haemorrhagic or ischaemic cardiovascular accidents, ischaemia, heart attack and haemorrhagia leading to tissue destruction, heart, kidney, respiratory or liver insufficiency, cancer, malign and benign tumours and neoplasia. The present invention further relates to methods for inducing the regeneration of cells, tissues, organs and organic systems such as the circulatory, nervous and endocrine systems. Finally, the present invention relates to methods for restoring immune response in an animal, in particular a human being.
58 Citations
93 Claims
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1-45. -45. (canceled)
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46. Immunogenic composition for modulating the immune system comprising a therapeutically effective amount of two or more either natural or synthetic antigen agents comprising pathogen-associated molecular patterns (PAMPS) and/or danger associated molecular patterns (DAMPS) selected from the group consisting of:
- (A) antigenic agents with molecular patterns associated with bacteria, (B) antigenic agents with molecular patterns associated with viruses;
(C) antigenic agents with molecular patterns associated with fungi and yeasts;
(D) antigenic agents with molecular patterns associated with protozoa;
(E) antigenic agents with molecular patterns associated with helminths and/or (F) antigenic agents with molecular patterns associated with prions and one or more physiologically acceptable carriers, excipients, diluents or solvents. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93)
- (A) antigenic agents with molecular patterns associated with bacteria, (B) antigenic agents with molecular patterns associated with viruses;
Specification