Wireless, Handheld, Tissue Oximetry Device

• US 20140046152A1
• Filed: 08/12/2013
• Published: 02/13/2014
• Est. Priority Date: 05/03/2012
• Status: Active Grant

• Current Assignee: ViOptix, Inc.
• Original Assignee: ViOptix, Inc.
• Inventors: Bechtel, Kate LeeAnn, Lloyd, Lester John, Heanue, Joseph, Solomon, Edward
• Granted Patent: US 9,398,870 B2
• Time in Patent Office: Days
• US Class Current: 600/323
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure
• CPC Class Codes: A61B 2090/306 using optical fibres
• CPC Class Codes: A61B 2090/395 with marking agent for marking skin or other tissue
• CPC Class Codes: A61B 2560/0431 Portable apparatus, e.g. comprising a handle or case
• CPC Class Codes: A61B 2560/0475 Special features of memory means, e.g. removable memory cards
• CPC Class Codes: A61B 2562/0271 Thermal or temperature sensors
• CPC Class Codes: A61B 2562/166 the sensor is mounted on a specially adapted printed circuit board
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/72 Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/74 Details of notification to user or communication with user or patient indicating measured values G01D7/00; user input means input or output arrangements for computers G06F3/00
• CPC Class Codes: A61B 5/7405 using sound
• CPC Class Codes: A61B 5/742 : using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/7475 : User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 90/11 : with guides for needles or instruments, e.g. arcuate slides or ball joints
• CPC Class Codes: A61B 90/39 : Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61M 35/003 : Portable hand-held applicators having means for dispensing or spreading integral media hand-held massage devices with liquid delivery A61H7/003

Abstract

A system includes an enclosure having a processor and a memory coupled to the processor. The enclosure includes a display coupled to the processor where the display is visible from an exterior of the enclosure; and a battery within the enclosure coupled to the processor and the display. The enclosure includes a probe tip coupled to an exterior of the enclosure. The probe tip includes first, second, and third sensor openings. A first distance between the first and second sensor openings is different than a second distance between the first and third sensor openings. The enclosure includes code stored in the memory where the code is executable by the processor, and includes code to receive first data associated with the first and second sensor openings, code to receive second data associated with the first and second sensor openings, and code to perform SRS using the first and the second data.

Claims

1. A system comprising:

an enclosure comprising;

a first printed circuit board, housed within the enclosure, the first printed circuit board comprising a processor and a memory, wherein the memory is coupled to the processor;

a display, coupled to the processor, wherein the display is visible from an exterior side of the enclosure;

a battery, housed within the enclosure, coupled to the processor and the display; and

a probe tip, coupled to an exterior side of the enclosure, comprising at least a first sensor opening, a second sensor opening, and a third sensor opening, wherein a first distance is between the first and second sensor openings, and a second distance is between the first and third sensor openings, and the first distance is different from the second distance; and

executable code, stored in the memory, wherein the executable code is executable by the processor, the executable code comprising a first code to receive first data associated with the first and second sensor openings of the first distance, a second code to receive second data associated with the first and second sensor openings of the second distance, and a third code to perform spatially-resolved spectroscopy using the first and second data.

2. The system of claim 1 wherein the first sensor opening comprises a light source and the second and the third sensor openings comprise light detectors.

3. The system of claim 1 wherein the first sensor opening comprises a light detector and the second and the third sensor openings comprise light sources.

4. The system of claim 1 wherein the probe tip comprises:

a first layer comprising a second printed circuit board comprising a first light source;

a second layer, below the first layer, comprising a third printed circuit board comprising a first light detector and a second light detector;

a third layer, between the first and second layer, comprising a first lens positioned below the first light source; and

a fourth layer, below the third layer, comprising a waveguide positioned below the first lens.

5. The system of claim 4 wherein the third printed circuit board comprises a first aperture positioned below the first lens.

6. The system of claim 4 wherein the waveguide comprises an optical fiber.

7. The system of claim 1 wherein the executable code comprises:

a fourth code to calculate an estimated oxygen saturation value based on the first and second data; and

a fifth code to cause the display to show the estimated oxygen saturation value.

8. The system of claim 1 wherein the spatially-resolved spectroscopy is dependent on the first distance and the second distance being different.

9. The system of claim 1 wherein:

at least one of the first, the second, and the third sensor opening comprises a light source; and

the probe tip comprises a temperature sensing unit positioned adjacent to the light source configured to generate temperature information that represents the temperature of the light source, and wherein the processor is configured to adjust a duty cycle of an oscillating control signal supplied to the light source to adjust the luminosity generated by the light source based on the temperature information if the temperature of the light source changes.

10. The system of claim 1 wherein the probe tip is rigidly attached to the housing.

11. The system of claim 10 wherein the probe tip comprises a pressure sensor for sensing pressure of the probe tip on tissue.

12. The system of claim 1, wherein the enclosure is ten inches in length or less and is five inches or less across lateral axes of the enclosure.

13. A method comprising:

enclosing in a housing a first printed circuit board comprising a processor and a memory, wherein the memory is coupled to the processor;

providing a display, coupled to the processor and the housing, wherein the display is visible from an exterior side of the housing;

enclosing a battery within the housing, wherein the battery is coupled to the processor and the display;

forming a structure of the housing to retain the probe tip, wherein the probe tip is coupled to an exterior side of the enclosure, and the probe tip comprises at least a first sensor opening, a second sensor opening, and a third sensor opening, wherein a first distance is between the first and second sensor openings, and a second distance is between the first and third sensor openings, and the first distance is different from the second distance;

configuring the probe tip to receive first data associated with the first and the second sensor openings;

configuring the probe tip to receive second data associated with the first and the third sensor openings; and

configuring the processor to perform spatially-resolved spectroscopy using the first and the second data to determine an oxygen saturation value.

14. The method of claim 13 further comprising:

providing a light source for the first sensor opening; and

providing light detectors for the second and the third sensor openings comprise light detectors.

15. The method of claim 13 further comprising;

providing a light detector for the first sensor opening; and

providing light sources for the second and the third sensor openings.

16. The method of claim 13 further comprising providing in the probe tip:

a first layer comprising a second printed circuit board comprising a first light source;

a second layer, below the first layer, comprising a third printed circuit board comprising a first light detector and a second light detector;

a third layer, between the first and second layer, comprising a first lens positioned below the first light source; and

a fourth layer, below the third layer, comprising a waveguide positioned below the first lens.

17. The method of claim 16 forming in the third printed circuit board a first aperture positioned to be below the first lens.

18. The method of claim 17 wherein the waveguide comprises an optical fiber.

19. The method of claim 13 further comprising:

configuring the processor to calculate an estimated oxygen saturation value based on the first and second data; and

configuring the processor to cause the display to show a normalized oxygen saturation value that is representative of the calculated estimated oxygen saturation value.

20. The method of claim 13 wherein the spatially-resolved spectroscopy is dependent on the first distance and the second distance being different.