Trajectory Guide Frame for MRI-Guided Surgeries

• US 20140066750A1
• Filed: 03/13/2013
• Published: 03/06/2014
• Est. Priority Date: 09/05/2012
• Status: Active Grant

• Current Assignee: Clearpoint Neuro, Inc.
• Original Assignee: MRI Interventions, Inc. (Clearpoint Neuro, Inc.)
• Inventors: Piferi, Peter, Ghidoli, Daniele, Pandey, Rajesh, Flores, Jesse
• Granted Patent: US 9,192,446 B2
• Time in Patent Office: Days
• US Class Current: 600/417
• CPC Class Codes: A61B 2017/00911 for fields applied by a magnetic resonance imaging system
• CPC Class Codes: A61B 2017/3407 including a base for support on the body
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 90/11 with guides for needles or instruments, e.g. arcuate slides or ball joints

Abstract

An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.

Claims

1. An MRI-guided interventional system for use with a patient and an interventional device, the system comprising:

a base configured to be secured to a body of the patient;

a trajectory guide frame including a targeting cannula, the targeting cannula having an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device, wherein the trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo;

a plurality of patient engagement structures on the base configured to penetrate tissue of the body and to space the base apart from the tissue; and

a plurality of fasteners configured to secure the base to the body.

2. The MRI-guided interventional system of claim 1 wherein the plurality of fasteners includes a plurality of screws.

3. The MRI-guided interventional system of claim 2 wherein:

the MRI-guided interventional system is configured for use with a head of the patient, the head having a skull covered by a scalp;

the base is configured to be secured to the head such that the plurality of engagement structures penetrate the scalp and space the base apart from the skull; and

the plurality of screws are configured to secure the base to the skull.

4. The MRI-guided interventional system of claim 3 wherein:

the base includes a base portion and a mounting member;

the targeting cannula is supported by the base portion; and

the mounting member is configured to be coupled to the base portion between the head and the base portion.

5. The MRI-guided interventional system of claim 3 wherein the plurality of patient engagement structures include a plurality of pins.

6. The MRI-guided interventional system of claim 3 wherein the plurality of patient engagement structures each have a sharp tip configured to pierce through the scalp.

7. The MRI-guided interventional system of claim 1 wherein each of the patient engagement structures has a distal tip to engage the body, and an extension length of the patient engagement structure is selectively adjustable, the extension length being the length of the patient engagement structure extending from the base to the distal tip.

8. The MRI-guided interventional system of claim 1 wherein the plurality of patient engagement structures includes at least three patient engagement structures.

9. A method for mounting an MRI-guided interventional system on a patient, the method comprising:

providing an MRI-guided interventional system including;

a base configured to be secured to a body of the patient;

a trajectory guide frame including a targeting cannula, the targeting cannula having an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device, wherein the trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo;

a plurality of patient engagement structures on the base; and

a plurality of fasteners configured to secure the base to the body;

mounting the base on the body such that the patient engagement structures penetrate tissue of the body and space the base apart from the tissue; and

securing the base to the body using the plurality of fasteners.

10. The method of claim 9 wherein the plurality of fasteners includes a plurality of screws.

11. The method of claim 10 wherein:

the MRI-guided interventional system is configured for use with a head of the patient, the head having a skull covered by a scalp;

mounting the base on the head includes mounting the base on the head such that the plurality of patient engagement structures penetrate the scalp and space the base apart from the skull; and

securing the base to the body using the plurality of screws includes securing the base to the skull using the plurality of screws.

12. The method of claim 11 wherein the step of securing the base to the skull using the plurality of screws includes driving the screws through the scalp and into the skull.

13. The method of claim 11 wherein:

the base includes a base portion and a mounting member; and

the method includes;

coupling the mounting member between the head and the base portion; and

supporting the targeting cannula on the base portion.

14. The method of claim 11 wherein the plurality of patient engagement structures include a plurality of pins.

15. The method of claim 11 wherein the plurality of patient engagement structures each have a sharp tip configured to pierce through the scalp.

16. The method of claim 9 wherein:

each of the patient engagement structures has a distal tip to engage the body; and

the method includes selectively adjusting an extension length of at least one of the patient engagement structures, the extension length being the length of the patient engagement structure extending from the base to the distal tip.

17. The method of claim 16 including executing the step of selectively adjusting the extension length of at least one of the patient engagement structures after the step of securing the base to the body using the plurality of fasteners.

18. The method of claim 9 wherein the plurality of patient engagement structures includes at least three patient engagement structures.

19. The method of claim 9 including placing a positioning tool on the body in a selected location, wherein mounting the base on the body includes mounting the base over the positioning tool to positively locate the base with respect to the selected location.

20. The method of claim 19 including pre-forming a puncture in the body, wherein the puncture is at the selected location.

21. The method of claim 9 including mounting the trajectory guide frame on the base after securing the base to the body using the plurality of fasteners.

22. The method of claim 21 including forming a burr hole in the body before or after securing the base to the body.

23. The method of claim 22 including using the trajectory guide frame to guide a drill bit to form the burr hole.