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THYROID HORMONE ANALOGS AND METHODS OF USE

  • US 20140072646A1
  • Filed: 08/26/2013
  • Published: 03/13/2014
  • Est. Priority Date: 09/15/2003
  • Status: Active Grant
First Claim
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1. A method for treating a condition amendable to angiogenesis comprising:

  • conjugating a thyroid hormone analog to a polymer forming a conjugated thyroid hormone analog;

    formulating the polymer into a nanoparticle, wherein the nanoparticle is less than 200 nanometers; and

    administering to a subject in need thereof an effective amount conjugated thyroid hormone wherein the administered thyroid hormone analog does not enter the cellular nucleus.

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