THYROID HORMONE ANALOGS AND METHODS OF USE
First Claim
Patent Images
1. A method for treating a condition amendable to angiogenesis comprising:
- conjugating a thyroid hormone analog to a polymer forming a conjugated thyroid hormone analog;
formulating the polymer into a nanoparticle, wherein the nanoparticle is less than 200 nanometers; and
administering to a subject in need thereof an effective amount conjugated thyroid hormone wherein the administered thyroid hormone analog does not enter the cellular nucleus.
1 Assignment
0 Petitions
Accused Products
Abstract
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
-
Citations
16 Claims
-
1. A method for treating a condition amendable to angiogenesis comprising:
-
conjugating a thyroid hormone analog to a polymer forming a conjugated thyroid hormone analog; formulating the polymer into a nanoparticle, wherein the nanoparticle is less than 200 nanometers; and administering to a subject in need thereof an effective amount conjugated thyroid hormone wherein the administered thyroid hormone analog does not enter the cellular nucleus. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
Specification