METHODS AND SYSTEMS FOR QUALIFYING PHYSIOLOGICAL VALUES BASED ON CROSS-CORRELATIONS

• US 20140073876A1
• Filed: 09/11/2012
• Published: 03/13/2014
• Est. Priority Date: 09/11/2012
• Status: Abandoned Application

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Nellcor Puritan Bennett LLC (Medtronic Plc)
• Inventors: Rodriguez-Llorente, Fernando, Wooder, Nicholas James
• Application Number:
  US13/609,680
• Publication Number:
  US 20140073876A1
• Time in Patent Office: Days
• US Class Current: 600/301
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7228 Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal modulation H03C
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity

Abstract

A physiological monitoring system may process a physiological signal such a photoplethysmograph signal from a subject. The system may determine physiological information, such as a physiological rate, from the physiological signal. The system may use search techniques and qualification techniques to determine one or more initialization parameters. The initialization parameters may be used to calculate and qualify a physiological rate. The system may use signal conditioning to reduce noise in the physiological signal and to improve the determination of physiological information. The system may use qualification techniques to confirm determined physiological parameters. The system may also use autocorrelation techniques, cross-correlation techniques, fast start techniques, and/or reference waveforms when processing the physiological signal.

Claims

1. A subject monitoring system for determining physiological information of a subject, comprising:

a sensor configured to generate an intensity signal, wherein the sensor detects light attenuated by the subject; and

processing equipment coupled to the sensor, wherein the processing equipment is configured to;

determine a value indicative of a physiological rate of the subject;

calculate a first cross-correlation sequence based on the intensity signal and a first reference waveform;

calculate a second cross-correlation sequence based on the intensity signal and a second reference waveform; and

determine whether to qualify the value indicative of the physiological rate of the subject based on the first cross-correlation sequence and the second cross-correlation sequence.

2. The system of claim 1, wherein the first reference waveform and the second reference waveform have different lengths.

3. The system of claim 1, wherein the first reference waveform comprises a first pulse shape, wherein the second reference waveform comprises a second pulse shape, and wherein the first pulse shape and the second pulse shape are different.

4. The system of claim 1, wherein the processing equipment is further configured to:

determine a first qualification metric based on the first cross-correlation sequence;

determine a second qualification metric based on the second cross-correlation sequence; and

determine whether to qualify the value indicative of the physiological rate based on the first qualification metric and the second qualification metric.

5. The system of claim 1, wherein the processing equipment is further configured to not use the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

6. The system of claim 1, wherein the processing equipment is further configured to filter the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

7. The system of claim 1, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.

8. A processing module for determining physiological information of a subject, wherein the processing module is configured to:

receive an intensity signal from a detector, wherein the detector detects light attenuated by the subject;

determine a value indicative of a physiological rate of the subject;

calculate a first cross-correlation sequence based on the intensity signal and a first reference waveform;

calculate a second cross-correlation sequence based on the intensity signal and a second reference waveform; and

determine whether to qualify the value indicative of the physiological rate of the subject based on the first cross-correlation sequence and the second cross-correlation sequence.

9. The processing module of claim 8, wherein the first reference waveform and the second reference waveform have different lengths.

10. The processing module of claim 8, wherein the first reference waveform comprises a first pulse shape, wherein the second reference waveform comprises a second pulse shape, and wherein the first pulse shape and the second pulse shape are different.

11. The processing module of claim 8, further configured to:

determine a first qualification metric based on the first cross-correlation sequence;

determine a second qualification metric based on the second cross-correlation sequence; and

determine whether to qualify the value indicative of the physiological rate based on the first qualification metric and the second qualification metric.

12. The processing module of claim 8, further configured to not use the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

13. The processing module of claim 8, further configured to filter the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

14. The processing module of claim 8, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.

15. A method for processing physiological information of a subject, comprising:

receiving an intensity signal from a detector, which detects light attenuated by the subject;

determining a value indicative of a physiological rate of the subject;

calculating a first cross-correlation sequence based on the intensity signal and a first reference waveform;

calculating a second cross-correlation sequence based on the intensity signal and a second reference waveform; and

determining, using processing equipment, whether to qualify the value indicative of the physiological rate of the subject based on the first cross-correlation sequence and the second cross-correlation sequence.

16. The method of claim 15, wherein the first reference waveform and the second reference waveform have different lengths.

17. The method of claim 15, wherein the first reference waveform comprises a first pulse shape, wherein the second reference waveform comprises a second pulse shape, and wherein the first pulse shape and the second pulse shape are different.

18. The method of claim 15, further comprising:

determining a first qualification metric based on the first cross-correlation sequence; and

determining a second qualification metric based on the second cross-correlation sequence, wherein determining whether to qualify the value indicative of the physiological rate comprises determining whether to qualify the value indicative of the physiological rate based on the first qualification metric and the second qualification metric.

19. The method of claim 15, further comprising not using the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

20. The method of claim 15, further comprising filtering the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

21. The method of claim 15, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.

22. A computer-readable medium for use in determining physiological information of a subject, the computer-readable medium having computer program instructions recorded thereon for:

receiving an intensity signal from a detector, which detects light attenuated by the subject;

determining a value indicative of a physiological rate of the subject;

calculating a first cross-correlation sequence based on the intensity signal and a first reference waveform;

calculating a second cross-correlation sequence based on the intensity signal and a second reference waveform; and

determining whether to qualify the value indicative of the physiological rate of the subject based on the first cross-correlation sequence and the second cross-correlation sequence.

23. The computer-readable medium of claim 22, wherein the first reference waveform and the second reference waveform have different lengths.

24. The computer-readable medium of claim 22, wherein the first reference waveform comprises a first pulse shape, wherein the second reference waveform comprises a second pulse shape, and wherein the first pulse shape and the second pulse shape are different.

25. The computer-readable medium of claim 22, having further computer program instructions recorded thereon for:

determining a first qualification metric based on the first cross-correlation sequence; and

determining a second qualification metric based on the second cross-correlation sequence, wherein determining whether to qualify the value indicative of the physiological rate comprises determining whether to qualify the value indicative of the physiological rate based on the first qualification metric and the second qualification metric.

26. The computer-readable medium of claim 22, having further computer program instructions recorded thereon for not using the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

27. The computer-readable medium of claim 22, having further computer program instructions recorded thereon for filtering the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

28. The computer-readable medium of claim 22, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.