METHODS AND SYSTEMS FOR CONDITIONING PHYSIOLOGICAL INFORMATION BASED ON A STABILITY FUNCTION

• US 20140073936A1
• Filed: 09/11/2012
• Published: 03/13/2014
• Est. Priority Date: 09/11/2012
• Status: Abandoned Application

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Nellcor Puritan Bennett LLC (Medtronic Plc)
• Inventors: Rodriguez-Llorente, Fernando, Engelbrecht, Pirow, Wooder, Nicholas James
• Application Number:
  US13/609,419
• Publication Number:
  US 20140073936A1
• Time in Patent Office: Days
• US Class Current: 600/476
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal

Abstract

A physiological monitoring system may determine physiological information, such as physiological rate information, from a physiological signal. The system may condition the physiological signal to assist in the determination of the physiological information. The system may generate a signal based on a stability function applied to the physiological signal. The stability function may include a Lyapunov function. The system may generate a difference signal based on the stability function, and modify the physiological signal based on the difference signal. The modification may include reducing, or otherwise limiting, some differences between adjacent values in the physiological signal, removing portions of the physiological signal, or other modifications.

Claims

1. A subject monitoring system for conditioning a physiological intensity signal, comprising:

a sensor configured to generate a physiological signal, wherein the sensor detects light attenuated by a subject; and

processing equipment coupled to the sensor, wherein the processing equipment is configured to;

generate a first signal based on a Lyapunov function applied to the physiological signal;

generate a difference signal based on the first signal; and

generate a modified physiological signal based on the difference signal.

2. The system of claim 1, wherein the processing equipment is further configured to:

identify one or more points of the difference signal that exceed a threshold; and

modify one or more points in the physiological signal that correspond to the one or more points of the difference signal.

3. The system of claim 2, wherein the processing equipment is further configured to determine a standard deviation of the difference signal, wherein the threshold is based on the standard deviation of the difference signal.

4. The system of claim 2, wherein the threshold is a predetermined value.

5. The system of claim 2, wherein the processing equipment is further configured to remove portions of the physiological signal associated with the one or more points of the difference signal that exceed the threshold.

6. The system of claim 2, wherein the processing equipment is further configured to identify a pair of two threshold crossings and intermediate points between the two threshold crossings of the difference signal.

7. The system of claim 1, wherein the physiological signal is a photoplethysmograph signal and wherein the processing equipment is further configured to determine a physiological rate of the subject based on the modified physiological signal.

8. A processing module for conditioning a physiological intensity signal, wherein the processing module is configured to:

receive a physiological signal derived from a detector output, wherein the detector detects light attenuated by a subject;

generate a first signal based on a Lyapunov function applied to the physiological signal;

generate a difference signal based on the first signal; and

generate a modified physiological signal based on the difference signal.

9. The processing module of claim 8, further configured to:

identify one or more points of the difference signal that exceed a threshold; and

modify one or more points in the physiological signal that correspond to the one or more points of the difference signal.

10. The processing module of claim 9, further configured to determine a standard deviation of the difference signal, wherein the threshold is based on the standard deviation of the difference signal.

11. The processing module of claim 9, wherein the threshold is a predetermined value.

12. The processing module of claim 9, further configured to remove portions of the physiological signal associated with the one or more points of the difference signal that exceed the threshold.

13. The processing module of claim 9, further configured to identify a pair of two threshold crossings and intermediate points between the two threshold crossings of the difference signal.

14. The processing module of claim 8, wherein the physiological signal is a photoplethysmograph signal, the processing module further configured to determine a physiological rate of the subject based on the modified physiological signal.

15. A method for conditioning a physiological intensity signal, comprising:

receiving, using processing equipment, a physiological signal derived from a detector output, wherein the detector detects light attenuated by a subject;

generating, using the processing equipment, a first signal based on a Lyapunov function applied to the physiological signal;

generating, using the processing equipment, a difference signal based on the first signal; and

generating, using the processing equipment, a modified physiological signal based on the difference signal.

16. The method of claim 15, further comprising identifying one or more points of the difference signal that exceed a threshold, wherein generating the modified physiological signal comprises modifying one or more points in the physiological signal that correspond to the one or more points of the difference signal.

17. The method of claim 16, further comprising determining a standard deviation of the difference signal, wherein the threshold is based on the standard deviation of the difference signal.

18. The method of claim 16, wherein the threshold is a predetermined value.

19. The method of claim 16, wherein generating the modified physiological signal comprises removing portions of the physiological signal associated with the one or more points of the difference signal that exceed the threshold.

20. The method of claim 16, wherein identifying the one more points of the difference signal that exceed the threshold comprises identifying a pair of two threshold crossings and intermediate points between the two threshold crossings of the difference signal.

21. The method of claim 15, wherein the physiological signal is a photoplethysmograph signal, the method further comprising determining a physiological rate of the subject based on the modified physiological signal.

22. A computer-readable medium for use in conditioning a physiological intensity signal, the computer-readable medium having computer program instructions recorded thereon for:

receiving a physiological signal derived from a detector output, wherein the detector detects light attenuated by a subject;

generating a first signal based on a Lyapunov function applied to the physiological signal;

generating a difference signal based on the first signal; and

generating a modified physiological signal based on the difference signal.

23. The computer-readable medium of claim 22, having further computer program instructions recorded thereon for:

identifying one or more points of the difference signal that exceed a threshold; and

modifying one or more points in the physiological signal that correspond to the one or more points of the difference signal.

24. The computer-readable medium of claim 23, having further computer program instructions recorded thereon for determining a standard deviation of the difference signal, wherein the threshold is based on the standard deviation of the difference signal.

25. The computer-readable medium of claim 23, wherein the threshold is a predetermined value.

26. The computer-readable medium of claim 23, having further computer program instructions recorded thereon for removing portions of the physiological signal associated with the one or more points of the difference signal that exceed the threshold.

27. The computer-readable medium of claim 23, having further computer program instructions recorded thereon for identifying a pair of two threshold crossings and intermediate points between the two threshold crossings of the difference signal.

28. The computer-readable medium of claim 22, wherein the physiological signal is a photoplethysmograph signal, the computer-readable medium having further computer program instructions recorded thereon for determining a physiological rate of the subject based on the modified physiological signal.