METHODS AND SYSTEMS FOR QUALIFYING PHYSIOLOGICAL VALUES BASED ON SYMMETRY ASSOCIATED WITH A CROSS-CORRELATION SEQUENCE

• US 20140073961A1
• Filed: 09/11/2012
• Published: 03/13/2014
• Est. Priority Date: 09/11/2012
• Status: Abandoned Application

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Nellcor Puritan Bennett LLC (Medtronic Plc)
• Inventors: Rodriguez-Llorente, Fernando, Wooder, Nicholas James
• Application Number:
  US13/609,548
• Publication Number:
  US 20140073961A1
• Time in Patent Office: Days
• US Class Current: 600/479
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02444 Details of sensor A61B5/02427 takes precedence
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

A physiological monitoring system may process a physiological signal such a photoplethysmograph signal from a subject. The system may determine physiological information, such as a physiological rate, from the physiological signal. The system may use search techniques and qualification techniques to determine one or more initialization parameters. The initialization parameters may be used to calculate and qualify a physiological rate. The system may use signal conditioning to reduce noise in the physiological signal and to improve the determination of physiological information. The system may use qualification techniques to confirm determined physiological parameters. The system may also use autocorrelation techniques, cross-correlation techniques, fast start techniques, and/or reference waveforms when processing the physiological signal.

Claims

1. A subject monitoring system for determining physiological information of a subject, comprising:

a sensor configured to generate an intensity signal, wherein the sensor detects light attenuated by the subject; and

processing equipment coupled to the sensor, wherein the processing equipment is configured to;

determine a value indicative of a physiological rate of the subject;

calculate a cross-correlation sequence based on the intensity signal and a reference waveform, wherein a characteristic of the reference waveform is based on the value indicative of the physiological rate of the subject;

calculate a metric indicative of a symmetry associated with the cross-correlation sequence; and

determine whether to qualify the value indicative of the physiological rate of the subject based on the metric.

2. The system of claim 1, wherein the processing equipment is further configured to:

select two segments from the cross-correlation sequence; and

determine symmetry between the two segments.

3. The system of claim 2, wherein the two segments are adjacent segments centered on a peak or valley of the cross-correlation sequence.

4. The system of claim 2, wherein the two segments begin at points in the cross-correlation sequence that are spaced apart from each other that are at approximately equal amplitudes.

5. The system of claim 1, wherein the reference waveform includes a pulse shape and wherein the characteristic of the reference waveform that is based on the value indicative of the physiological rate is one or more of a period of the pulse shape and the pulse shape.

6. The system of claim 1, wherein the processing equipment is further configured to not use the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

7. The system of claim 1, wherein the processing equipment is further configured to filter the value indicative of the physiological rate in a rate filter and wherein a filter weight associated with the value is decreased when the value is not qualified.

8. The system of claim 1, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.

9. A processing module for determining physiological information of a subject, wherein the processing module is configured to:

receive an intensity signal from a detector, wherein the detector detects light attenuated by the subject;

determine a value indicative of a physiological rate of the subject;

calculate a cross-correlation sequence based on the intensity signal and a reference waveform, wherein a characteristic of the reference waveform is based on the value indicative of the physiological rate of the subject;

calculate a metric indicative of a symmetry associated with the cross-correlation sequence; and

determine whether to qualify the value indicative of the physiological rate of the subject based on the metric.

10. The processing module of claim 9, further configured to:

select two segments from the cross-correlation sequence; and

determine symmetry between the two segments.

11. The processing module of claim 10, wherein the two segments are adjacent segments centered on a peak or valley of the cross-correlation sequence.

12. The processing module of claim 10, wherein the two segments begin at points in the cross-correlation sequence that are spaced apart from each other that are at approximately equal amplitudes.

13. The processing module of claim 9, wherein the reference waveform includes a pulse shape and wherein the characteristic of the reference waveform that is based on the value indicative of the physiological rate is one or more of a period of the pulse shape and the pulse shape.

14. The processing module of claim 9, further configured to not use the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

15. The processing module of claim 9, further configured to filter the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

16. The processing module of claim 9, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.

17. A method for processing physiological information of a subject, comprising:

receiving an intensity signal from a detector, which detects light attenuated by the subject;

determining a value indicative of a physiological rate of the subject;

calculating a cross-correlation sequence based on the intensity signal and a reference waveform, wherein a characteristic of the reference waveform is based on the value indicative of the physiological rate of the subject;

calculating a metric indicative of a symmetry associated with the cross-correlation sequence; and

determining, using processing equipment, whether to qualify the value indicative of the physiological rate of the subject based on the metric.

18. The method of claim 17, further comprising selecting two segments from the cross-correlation sequence, wherein calculating the metric indicative of symmetry comprises determining symmetry between the two segments.

19. The method of claim 18, wherein the two segments are adjacent segments centered on a peak or valley of the cross-correlation sequence.

20. The method of claim 18, wherein the two segments begin at points in the cross-correlation sequence that are spaced apart from each other that are at approximately equal amplitudes.

21. The method of claim 17, wherein the reference waveform includes a pulse shape and wherein the characteristic of the reference waveform that is based on the value indicative of the physiological rate is one or more of a period of the pulse shape and the pulse shape.

22. The method of claim 17, further comprising not using the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

23. The method of claim 17, further comprising filtering the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

24. The method of claim 17, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.

25. A computer-readable medium for use in determining physiological information of a subject, the computer-readable medium having computer program instructions recorded thereon for:

receiving an intensity signal from a detector, which detects light attenuated by the subject;

determining a value indicative of a physiological rate of the subject;

calculating a cross-correlation sequence based on the intensity signal and a reference waveform, wherein a characteristic of the reference waveform is based on the value indicative of the physiological rate of the subject;

calculating a metric indicative of a symmetry associated with the cross-correlation sequence; and

determining whether to qualify the value indicative of the physiological rate of the subject based on the metric.

26. The computer-readable medium of claim 25, having further computer program instructions recorded thereon for selecting two segments from the cross-correlation sequence, wherein calculating the metric indicative of symmetry comprises determining symmetry between the two segments.

27. The computer-readable medium of claim 26, wherein the two segments are adjacent segments centered on a peak or valley of the cross-correlation sequence.

28. The computer-readable medium of claim 26, wherein the two segments begin at points in the cross-correlation sequence that are spaced apart from each other that are at approximately equal amplitudes.

29. The computer-readable medium of claim 25, wherein the reference waveform includes a pulse shape and wherein the characteristic of the reference waveform that is based on the value indicative of the physiological rate is one or more of a period of the pulse shape and the pulse shape.

30. The computer-readable medium of claim 25, having further computer program instructions recorded thereon for not using the value indicative of the physiological rate in calculating a display rate when the value is not qualified.

31. The computer-readable medium of claim 25, having further computer program instructions recorded thereon for filtering the value indicative of the physiological rate in a rate filter, wherein a filter weight associated with the value is decreased when the value is not qualified.

32. The computer-readable medium of claim 25, wherein the intensity signal is a photoplethysmograph signal and wherein the value indicative of the physiological rate is a value indicative of a pulse rate.