Method and System for Providing Basal Profile Modification in Analyte Monitoring and Management Systems

• US 20140074061A1
• Filed: 11/15/2013
• Published: 03/13/2014
• Est. Priority Date: 11/04/2005
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Inventors: Sloan, Mark Kent, Hayter, Gary Alan
• Granted Patent: US 9,323,898 B2
• Time in Patent Office: Days
• US Class Current: 604/504
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.

Claims

1. A method, comprising:

retrieving from a data storage unit using one or more processing units, a first medication delivery profile for administration of a medication during a plurality of time segments;

monitoring, using a sensor, an analyte level during the plurality of time segments;

determining, using the one or more processing units, a frequency of the analyte level deviating from a predetermined level during one or more of the plurality of time segments; and

determining, using the one or more processing units, a second medication delivery profile for administration of the medication during the one or more of the plurality of time segments when the frequency of the analyte level deviating from the predetermined level exceeds a predetermined threshold.

2. The method of claim 1, further comprising outputting a notification associated with the second medication delivery profile.

3. The method of claim 2, wherein the notification is output visually and/or audibly.

4. The method of claim 1, further comprising executing the determined second medication delivery profile.

5. The method of claim 4, wherein the medication is insulin, the analyte level monitored is a glucose level, and executing the determined second medication delivery profile includes one or more of reducing extreme glucose excursions, automating or semi-automating a routine or a regular bolus dosing, or adjusting a mean glucose value.

6. The method of claim 4, wherein the executing the determined second medication delivery profile includes modifying a currently running medication delivery profile prior to its completion.

7. The method of claim 1, further comprising storing the determined second medication delivery profile in the data storage unit.

8. The method of claim 1, wherein the first medication delivery profile is based at least in part on the plurality of time segments and one or more patient specific parameters.

9. The method of claim 8, wherein the medication is insulin, the monitored analyte level is a glucose level, and the one or more patient specific parameters include one or more of an insulin sensitivity, a type of insulin being administered, one or more activities during the plurality of time segments, or carbohydrate intake during the plurality of time segments.

10. The method of claim 1, wherein the first medication delivery profile is based at least in part on a frequency of bolus dosing of the medication during the plurality of time segments and a level of medication on board.

11. An apparatus, comprising:

one or more processing units; and

a data storage unit operatively coupled to the one or more processing units, the data storage unit having stored therein executable programming instructions which, when executed by the one or more processing units, is configured to retrieve a first medication delivery profile for administration of a medication during a plurality of time segments from the data storage unit to monitor an analyte level during the plurality of time segments, to determine a frequency of the analyte level deviating from a predetermined level during one or more of the plurality of time segments, and to determine a second medication delivery profile for administration of the medication during the one or more of the plurality of time segments when the frequency of the analyte level deviating from the predetermined level exceeds a predetermined threshold.

12. The apparatus of claim 11, further comprising an output unit operatively coupled to the one or more processing units configured to output a notification associated with the second medication delivery profile.

13. The apparatus of claim 12, wherein the notification is output visually and/or audibly.

14. The apparatus of claim 11, wherein the executable programming instructions stored in the data storage unit, which, when executed by the one or more processing units, executes the determined second medication delivery profile.

15. The apparatus of claim 14, wherein the medication is insulin, the analyte level monitored is a glucose level, and executing the determined second medication delivery profile includes one or more of reducing extreme glucose excursions, automating or semi-automating a routine or a regular bolus dosing, or adjusting a mean glucose value.

16. The apparatus of claim 14, wherein the executable programming instructions stored in the data storage unit, which, when executed by the one or more processing units, is further configured to modify a currently running medication delivery profile prior to its completion.

17. The apparatus of claim 11, wherein the determined second medication delivery profile is stored in the data storage unit.

18. The apparatus of claim 11, wherein the first medication delivery profile is based at least in part on the plurality of time segments and one or more patient specific parameters.

19. The apparatus of claim 18, wherein the medication is insulin, the monitored analyte level is a glucose level, and the one or more patient specific parameters include one or more of an insulin sensitivity, a type of insulin being administered, one or more activities during the plurality of time segments, or carbohydrate intake during the plurality of time segments.

20. The apparatus of claim 11, wherein the first medication delivery profile is based at least in part on a frequency of bolus dosing of the medication during the plurality of time segments and a level of medication on board.