PISTON PUMP DEVICES
First Claim
Patent Images
1. A drug pump assembly comprising:
- two piston pump devices, each comprising (i) a vial having a drug reservoir therein, (ii) a piston movable within the vial for forcing drug out of an outlet of the reservoir, and (iii) a pump for actuating the piston;
a first mixing chamber downstream of the reservoirs; and
first fluid conduits connecting the outlets of the reservoirs with the first mixing chamber and a second fluid conduit connecting the first mixing chamber with a drug delivery vehicle downstream thereof.
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Abstract
Drug pump devices with syringe or pen-injection configurations may utilize pre-filled drug vials or cartridges; the prefilled vials may be equipped with mechanisms for stirring their contents and/or changing a chemical environment therein to improve therapies. To facilitate combination therapies, multiple drug pump devices may be assembled into a larger system. Lancet insertion devices for use in conjunction with the drug pump devices may feature improved safety characteristics and/or mechanisms for minimizing pain and discomfort.
41 Citations
20 Claims
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1. A drug pump assembly comprising:
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two piston pump devices, each comprising (i) a vial having a drug reservoir therein, (ii) a piston movable within the vial for forcing drug out of an outlet of the reservoir, and (iii) a pump for actuating the piston; a first mixing chamber downstream of the reservoirs; and first fluid conduits connecting the outlets of the reservoirs with the first mixing chamber and a second fluid conduit connecting the first mixing chamber with a drug delivery vehicle downstream thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for treating a target using an assembly comprising two piston pump devices, each comprising (i) a vial having a drug reservoir therein, (ii) a piston movable within the vial for forcing drug out of an outlet of the reservoir, and (iii) a pump for actuating the piston, the method comprising:
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actively mixing liquids released from the drug reservoirs of the two piston pump devices in a mixing chamber; and delivering the mixed liquid to the target via fluid conduits. - View Dependent Claims (13, 14, 15, 16)
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17. A method for treating a target using a drug pump assembly comprising two drug reservoirs fluidically connectable to an injection site in the target, the method comprising:
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providing a first therapeutic fluid from a first one of the reservoirs to the target; and subsequently providing a second therapeutic fluid, different from the first therapeutic fluid, from a second one of the reservoirs to the target, wherein the first therapeutic fluid pharmacokinetically affects a local environment of the target and the second therapeutic fluid comprises an active ingredient for treating the target.
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18. A method for treating a target using a drug pump assembly comprising two drug reservoirs and a mixing chamber, the method comprising:
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delivering a first therapeutic fluid from a first one of the reservoirs to the mixing chamber; providing a second therapeutic fluid, different from the first therapeutic fluid, from a second one of the reservoirs to the mixing chamber; mixing the first and second therapeutic fluids in the mixing chamber; and delivering the mixed first and second therapeutic fluids to the target, wherein the first therapeutic fluid comprises an active ingredient for treating the target and the second therapeutic fluid activates the active ingredient of the first fluid.
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19. A clinical trial method using a drug pump assembly comprising two drug reservoirs, the method comprising:
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delivering a therapeutic fluid from a first one of the reservoirs to a target within a patient and measuring a response of the target thereto; delivering a physiological saline solution from a second one of the reservoirs to the target and measuring a response of the target thereto; and comparing the responses of the target to the therapeutic fluid and the physiological saline solution, respectively, to thereby determine an effect of the therapeutic fluid.
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20-60. -60. (canceled)
Specification