Biosensor Calibration Method

• US 20140080167A1
• Filed: 03/14/2013
• Published: 03/20/2014
• Est. Priority Date: 09/14/2012
• Status: Active Grant

• Current Assignee: Tanita Corporation (Tanita)
• Original Assignee: Tanita Corporation (Tanita)
• Inventors: IKEDA, Satoshi, Kose, Mariko, Murayama, Tatsuro, Kinoshita, Yuri
• Granted Patent: US 8,975,080 B2
• Time in Patent Office: Days
• US Class Current: 435/25
• CPC Class Codes: C12Q 1/26 involving oxidoreductase
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: Y10T 436/10 Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
• CPC Class Codes: Y10T 436/104998 Glucose, ketone, nitrate standard or control
• CPC Class Codes: Y10T 436/144444 Glucose

Abstract

A biosensor calibration method configured to measure a concentration of a specific substance contained in sample liquid to be measured, including: a first step configured to acquire a first output value that is output by the biosensor when first calibration liquid is brought into contact with the biosensor; a second step configured to acquire a second output value that is output by the biosensor when second calibration liquid having a different concentration from that of the first calibration liquid is continuously brought into contact with the biosensor after the first step and determine time for replacement of the biosensor on the basis of the first output value and the second output value.

Claims

1. A biosensor calibration method configured to measure a concentration of a specific substance contained in sample liquid to be measured, comprising:

a first step of acquiring a first output value that is output by the biosensor when first calibration liquid is brought into contact with the biosensor; and

a second step of acquiring a second output value that is output by the biosensor when second calibration liquid having a different concentration from that of the first calibration liquid is continuously brought into contact with the biosensor after the first step and determining time for replacement of the biosensor on the basis of the first output value and the second output value.

2. The biosensor calibration method according to claim 1, wherein the concentration of the second calibration liquid is higher than the concentration of the first calibration liquid.

3. The biosensor calibration method according to claim 1, wherein the second calibration liquid has a concentration twice to six times that of the first calibration liquid.

4. The biosensor calibration method according to claim 1, wherein a determination of the time for replacement in the second step is a determination of whether or not the first output value and the second output value satisfy the relationship

(first output value×

n)×

(1−

0.35)≦

second output value≦

(first output value×

n)×

(1+0.05) (where, n=concentration of the second calibration liquid/concentration of the first calibration liquid).

5. The biosensor calibration method according to claim 1, further comprising a step of cleaning the biosensor after the second step.

6. The biosensor calibration method according to claim 1, further comprising a first notifying step of encouraging a user to bring the second calibration liquid into contact with the biosensor from 6 seconds to 20 seconds after the contact of the first calibration liquid.

7. The biosensor calibration method according to claim 1, further comprising a second notifying step of encouraging the user to clean the biosensor from 6 seconds to 20 seconds after the contact of the second calibration liquid.