Method and apparatus for improving fluidic flow and sample capture

• US 20140100483A1
• Filed: 12/10/2013
• Published: 04/10/2014
• Est. Priority Date: 12/31/2003
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Lum, Paul
• Granted Patent: US 9,561,000 B2
• Time in Patent Office: Days
• US Class Current: 600/583
• CPC Class Codes: A61B 2017/3437 with means for removing or absorbing fluid, e.g. wicks or absorbent pads
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150152 by an adequate mechanical impact on the puncturing location
• CPC Class Codes: A61B 5/150167 Adjustable piercing speed of skin piercing element, e.g. blade, needle, lancet or canula, for example with varying spring force or pneumatic drive
• CPC Class Codes: A61B 5/150175 Adjustment of penetration depth
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150419 comprising means for capillary action
• CPC Class Codes: A61B 5/150427 Specific tip design, e.g. for improved penetration characteristics
• CPC Class Codes: A61B 5/15045 comprising means for capillary action
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150572 Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
• CPC Class Codes: A61B 5/15101 Details
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15123 comprising magnets or solenoids
• CPC Class Codes: A61B 5/15151 Each piercing element being stocked in a separate isolated compartment
• CPC Class Codes: A61B 5/15161 Characterized by propelling the piercing element in a radial direction relative to the disc
• CPC Class Codes: A61B 5/15176 Stocking means comprising cap, cover, sheath or protection for aseptic stocking
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood

Abstract

A body fluid sampling device for use on a patient includes at least one penetrating member positioned in the cartridge and a sample port for receiving a body fluid. A channel is coupled to the sample port and the sample chamber. At least a portion of the channel is a capillary channel positioned adjacent to the sample chamber. A mesh membrane is and provides that the body fluid contacts the channel regardless of an orientation of body fluid sampling device.

Claims

1. A body fluid sampling device for use on a patient, comprising:

a cartridge;

at least one penetrating member positioned in the cartridge;

a sample port for receiving a body fluid in response to a puncturing event by the at least one penetrating member;

a sample chamber;

a channel coupled to the sample port and the sample chamber, at least a portion of the channel being a capillary channel positioned adjacent to the sample chamber; and

a mesh membrane positioned in the channel and at the sample port or adjacent to the sample port to guide a flow of the body fluid through at least a portion of the capillary channel with the mesh providing that the body fluid contacts the channel regardless of an orientation of body fluid sampling device.

2. The device of claim 1, further comprising:

at least one electrode positioned in the sample chamber and configured to determine an amount of an analyte in the body fluid

3. The device of claim 1, wherein the mesh membrane and channel are configured to provide a transport of the body fluid to the sample chamber and a measurement in less than 10 seconds.

4. The device of claim 1, further comprising:

a processor coupled to the controllable penetrating member and providing a controllable velocity of the at least one penetrating member.

5. The device of claim 1, wherein the mesh membrane is oriented perpendicular to a path of the at least one penetrating member.

6. The device of claim 1, wherein the mesh membrane is oriented to intersect a path of the penetrating member.

7. The device of claim 1, wherein further comprising:

a PET film hydrophobic coupled to topside sections of the capillary channel

8. The device of claim 7, further comprising:

a hydrophobic double-sided adhesive layer coupled to at least a portion of the capillary channel.

9. The device of claim 1, wherein an inner fluidic channel region of the capillary channel includes a sandwich structure of a top PET film or fluidic mesh structures and a bottom PET surface.

10. The device of claim 9, wherein PET surfaces abutting the mesh structures are hydrophilic.

11. The device of claim 1, further comprising:

an adhesive integrated with the mesh membrane.

12. The device of claim 11, wherein the adhesive is hydrophobic.

13. The device of claim 12, wherein the mesh and adhesive reduce fluidic flow where flow is not desirable

14. The device of claim 1, further comprising:

hydrophobic and hydrophilic adhesives within at least a portion of the mesh membrane to enhance fluidic capture and transport flow.

15. The device of claim 1, further comprising:

a plurality of wicking materials positioned around at least a portion of the cartridge.

16. The device of claim 1, further comprising:

a mesh membrane positioned around at least a portion of the cartridge.

17. The device of claim 1, wherein the mesh is pliable enough to permit a relaxation with maintenance of contact at or near a skin surface.

18. The device of claim 1, wherein the mesh is configured to provide for body fluid travel in only travel in a direction towards an analyte detecting member.

19. The device of claim 1, wherein the mesh is configured to provide for receipt of body fluid and a distribution of the body fluid over a uniform surface.

20. The device of claim 1, wherein the mesh is a single mesh structure.

21. The device of claim 1, wherein the mesh is a double mesh structure.