SOFT TISSUE IMPLANTS AND METHODS FOR MAKING SAME

• US 20140100590A1
• Filed: 03/29/2013
• Published: 04/10/2014
• Est. Priority Date: 09/12/2005
• Status: Active Grant

• Current Assignee: Proxy Biomedical Limited
• Original Assignee: Proxy Biomedical Limited
• Inventors: GINGRAS, PETER, King, Dean
• Granted Patent: US 9,750,594 B2
• Time in Patent Office: Days
• US Class Current: 606/151
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence

Abstract

The present invention features soft tissue implants comprising major and minor struts and methods for making same. The implants can includes a biocompatible film that is rendered porous due to the inclusion of uniformly or non-uniformly patterned cells, and the film has a thickness of less than about 0.015 inches in the event the starting material is non-porous and less than about 0.035 inches in the event the starting material is a microporous film. Multi-film implants can also be made.

Claims

1. A non-woven soft tissue implant comprising a porous biocompatible film having a plurality of cells, a thickness of less than about 0.015 inches, a plurality of major struts having a width of about 0.020 inches to about 0.100 inches and a plurality of minor struts having a width of about 0.001 inches to about 0.024 inches.

2. The non-woven soft tissue implant of claim 1, wherein the porous biocompatible film comprises a non-absorbable polymer or copolymer.

4. The non-woven soft tissue implant of claim 1, wherein the porous biocompatible film comprises an absorbable polymer or copolymer.

6. The non-woven soft tissue implant of claim 1, wherein the porous biocompatible film comprises a biological material.

9. The non-woven soft tissue implant of claim 1, wherein one or more of the cells in the plurality of cells has a diameter, measured along the longest axis of the cell, of about 10μ

to about 10,000μ

.

15. The non-woven soft tissue implant of claim 1, wherein the thickness of the porous biocompatible film is or is less than about 0.014 inches, is or is less than about 0.013 inches, is or is less than about 0.012 inches, is or is less than about 0.011 inches, is or is less than about 0.010 inches, is or is less than about 0.009 inches, is or is less than about 0.008 inches, is or is less than about 0.007 inches, is or is less than about 0.006 inches, is or is less than about 0.005 inches, is or is less than about 0.004 inches, is or is less than about 0.003 inches, is or is less than about 0.002 inches, or is about 0.001 inch.

16. The non-woven soft tissue implant of claim 1, wherein the porous biocompatible film has atraumatic edges.

19. The non-woven soft tissue implant of claim 1, wherein the plurality of cells comprises a cell pattern containing undulating elements comprising a sinusoidal element.

20. The non-woven soft tissue implant of claim 1, wherein each of the cells in the plurality of cells has a plurality of undulating elements in the form of a repeating pattern.

21. The non-woven soft tissue implant of claim 20, wherein the undulating elements are in phase.

24. The non-woven soft tissue implant of claim 1, wherein the pattern of the plurality of cells imparts force displacement characteristics that approximates those of the structure being repaired.

3. (canceled)

5. (canceled)

7-8. -8. (canceled)

10-14. -14. (canceled)

17-18. -18. (canceled)

22-23. -23. (canceled)

25. A non-woven soft tissue implant comprising a first porous biocompatible film having a plurality of cells and a second porous biocompatible film having a plurality of cells, the thickness of the implant being less than about 0.015 inches, wherein the first and/or second porous biocompatible film comprises a plurality of major struts having a width of about 0.020 inches to about 0.100 inches and a plurality of minor struts having a width of about 0.001 inches to about 0.024 inches.

26. The non-woven soft tissue implant of claim 25, wherein the first film and the second film consist of the same material or materials.

27. The non-woven soft tissue implant of claim 25, wherein the first film and the second film consist of different materials.

28. The non-woven soft tissue implant of claim 27, wherein the first film or the second film includes a bioresorbable material and the rate at which the first film is resorbed within a body is different from the rate at which the second film is resorbed within the body.

29. The non-woven soft tissue implant of claim 25, wherein the first film and the second film are of substantially the same size and a surface of the first film adheres to a surface of the second film.

32. The non-woven soft tissue implant of claim 25, wherein the porous biocompatible film comprises an absorbable polymer or copolymer.

36. The non-woven soft tissue implant of claim 25, wherein the first film or the second film comprises a cell having a diameter, measured along the longest axis of the cell, of about 10μ

to about 10,000μ

;

of about 1,500μ

to about 5,000μ

;

or of about 50μ

to about 100μ

.

40. The non-woven soft tissue implant of claim 25, further comprising a film that increases tear resistance.

30-31. -31. (canceled)

33-35. -35. (canceled)

37-39. -39. (canceled)

41-48. -48. (canceled)

49. A non-woven soft tissue implant comprising a cell block shown in FIG. 13A.