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Crush resistant delayed-release dosage forms

  • US 20140112984A1
  • Filed: 12/27/2013
  • Published: 04/24/2014
  • Est. Priority Date: 02/04/2005
  • Status: Abandoned Application
First Claim
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1. A dosage form comprising a physiologically effective amount of a physiologically active substance (A), a synthetic, semi-synthetic or natural polymer (C), optionally one or more physiologically acceptable auxiliary substances (B) and optionally a synthetic, semi-synthetic or natural wax (D), wherein the dosage form exhibits a resistance to crushing of at least 400 N, wherein under physiological conditions the release of the physiologically active substance (A) from the dosage form is at least partially delayed, wherein the physiologically active substance (A) consists of oxycodone, a physiologically acceptable derivative thereof, and wherein the polymer (C) is polyethylene oxide (PEO).

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