LASER EYE SURGERY SYSTEM CALIBRATION

• US 20140128853A1
• Filed: 11/01/2013
• Published: 05/08/2014
• Est. Priority Date: 11/02/2012
• Status: Active Grant

• Current Assignee: AMO Development LLC (Johnson & Johnson)
• Original Assignee: OptiMedica Corporation (Johnson & Johnson)
• Inventors: Angeley, David, Woodley, Bruce, Dewey, David, Simoneau, Mike, Schuele, Georg
• Granted Patent: US 10,314,746 B2
• Time in Patent Office: Days
• US Class Current: 606/4
• CPC Class Codes: A61F 2009/00846 Eyetracking
• CPC Class Codes: A61F 2009/0087 Lens
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/00887 Cataract
• CPC Class Codes: A61F 2009/00889 Capsulotomy
• CPC Class Codes: A61F 9/00827 Refractive correction, e.g. lenticle
• CPC Class Codes: A61F 9/009 Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses apparatus for eye examination A61B3/0008

Abstract

The amount of energy to provide optical breakdown can be determined based on mapped optical breakdown thresholds of the treatment volume, and the laser energy can be adjusted in response to the mapped breakdown thresholds. The mapping of threshold energies can be combined with depth and lateral calibration in order to determine the location of optical breakdown along the laser beam path for an amount of energy determined based on the mapping. The mapping can be used with look up tables to determine mapped locations from one reference system to another reference system.

Claims

1. A method of treating an eye, the method comprising:

mapping a plurality of laser beam focus locations comprising coordinate locations of a laser delivery system;

generating a treatment table comprising a plurality of target locations of the eye; and

adjusting the plurality of target locations of the eye based on the mapped plurality of laser beam focus locations so as to treat the eye at the plurality of target locations with the laser delivery system.

2. The method of claim 1, wherein the plurality of laser beam focus locations comprise a plurality of measured locations of optical breakdown along an optical path of the laser delivery system and wherein the plurality of target locations of the eye comprise a plurality of target distances along the optical and wherein the plurality of target distances along the optical path is adjusted based on the plurality of measured locations of optical breakdown along the optical path.

3. The method of claim 1, wherein the plurality of locations is mapped with a first lens and the patient is treated with a second lens, the second lens replacing the first lens along an optical path of the laser beam, wherein the first lens has a first measured location along the optical path of the laser beam and the second lens has a second measured location along the optical path of the laser beam spaced apart from the eye and wherein the plurality of target locations is adjusted based on the first measured location and the second measured location.

4. The method of claim 3, wherein the first lens comprises first a first aspheric surface to correct first aberrations and the second lens comprises a second aspheric surface to correct second aberrations.

5. The method of claim 3, wherein the first lens comprises first distortions and the second lens comprises second distortions and wherein the distortions of the second lens are corrected based on distortions of the first lens.

6. The method of claim 3, wherein the first lens comprises a first optical power and the second lens comprises a second optical power, the first optical power similar to the second optical power.

7. The method of claim 3, wherein the first measured location corresponds to a posterior surface of the first biconvex lens placed a first distance from the anterior surface of the eye within a first range from about 1 mm to about 10 mm and wherein the second measured location of the biconvex lens comprises a posterior surface of the second biconvex lens placed within a second range from about 1 mm to about 10 mm from the anterior surface of the eye.

8. The method of claim 3, wherein the first lens comprises a first biconvex lens and the second lens comprises a second biconvex lens and wherein the first biconvex lens comprises a first posterior surface having a first vertex and the second biconvex lens comprises a second posterior surface having a second vertex, and the first vertex and the second vertex are placed at locations way from a location of the vertex the cornea.

9. The method of claim 1, wherein an output energy of the laser is adjusted in response to an optical breakdown energy of a plurality of optical breakdown locations.

10. The method of claim 1, further comprising:

a patient interface comprising an optically transmissive structure having a posterior surface and an anterior surface, the optically transmissive structure comprising one or more of a lens, a plate or a wedge;

a patient measurement system configured to measure tissue of the eye, the patient measurement system configured to measure a location of one or more of the posterior surface or the anterior surface of the patient interface along an axis of the optical delivery system;

wherein the processor is configured to adjust the treatment table in response to the location of the one or more of the posterior surface or the anterior surface along the axis.

11. The method of claim 10, wherein the processor is configured to adjust the treatment table in response to a location of the posterior surface and a location of the anterior surface along the axis and wherein the processor is configured to determine a thickness of the one or more of the lens the plate or the wedge.

12. The method of claim 11, wherein the one or more of the lens, the plate or the wedge comprises the lens, the lens having a thickness, and wherein the treatment table is adjusted in response to the location of the posterior surface along the axis and the thickness of the lens.

13. An apparatus to treat an eye, the apparatus comprising:

a laser to generate a pulsed laser beam;

an optical delivery system coupled to the laser; and

a processor coupled to the laser and the optical delivery system, the processor configured to generate a treatment table comprising a plurality of target locations of the eye and adjust the plurality of target locations of the eye in response to a mapped plurality of laser beam focus locations.

14. The apparatus of claim 13, wherein the processor is configured to map the plurality of laser beam focus locations comprising coordinate locations of a laser delivery system so as to treat the eye at the plurality of target locations with the laser delivery system.

15. The apparatus of claim 13, further comprising:

a patient interface comprising an optically transmissive structure having a posterior surface and an anterior surface, the optically transmissive structure comprising one or more of a lens, a plate or a wedge;

a patient measurement system configured to measure tissue of the eye, the patient measurement system configured to measure a location of one or more of the posterior surface or the anterior surface of the patient interface along an axis of the optical delivery system;

wherein the processor is configured to adjust the treatment table in response to the location of the one or more of the posterior surface or the anterior surface along the axis.

16. The apparatus of claim 15, wherein the processor is configured to adjust the treatment table in response to a location of the posterior surface and a location of the anterior surface along the axis and wherein the processor is configured to determine a thickness of the one or more of the lens the plate or the wedge.

17. The apparatus of claim 16, wherein the one or more of the lens, the plate or the wedge comprises the lens, the lens having a thickness, and wherein the treatment table is adjusted in response to the location of the posterior surface along the axis and the thickness of the lens.

18. A method of treating an eye, the method comprising:

determining a plurality of threshold amounts of laser beam energy to induce optical breakdown at a plurality of laser beam focus locations;

generating a treatment table comprising a plurality of target locations of the eye; and

adjusting the laser beam pulse energy at the plurality of target locations in response to the plurality of threshold amounts.

19. The method of claim 18, wherein the laser beam energy comprises an output laser beam energy per pulse for each of the plurality of threshold amounts, the method further comprising decreasing the laser beam output energy per pulse below the plurality of threshold amounts and providing optical breakdown of the eye with the laser beam output energy per pulse below the plurality of threshold amounts.

20. The method of claim 18, wherein determining the plurality of threshold amounts comprises measuring the plurality of threshold amounts at each of the plurality of laser beam focus locations.

21. The method of claim 18, wherein the plurality of threshold amounts comprises a first plurality of threshold amounts at a first plurality of laser beam focus locations corresponding to a first treatment region of the eye and a second plurality of threshold amounts at a second plurality of laser beam focus locations corresponding to a second treatment region of the eye and wherein the laser beam pulse energy is decreased below the first plurality of threshold amounts to treat the second region of the eye with optical breakdown.

22. The method of claim 18, wherein each of the plurality of target locations comprises a plurality of coordinate references corresponding to a depth along an axis of the eye and first and second dimensions transverse to the axis of the eye, and wherein the plurality of target locations comprises a first plurality of target locations at a first depths along the axis of the eye and a second plurality of target locations at second depths along the axis of the eye and wherein the laser beam pulse energy comprises first amounts at the first plurality of target locations and second amounts at the second plurality of target locations, the first amounts comprising at least about twice the second amounts.

23. The method of claim 22, wherein the first amounts and the second amounts provide optical breakdown with pulse energies exceeding the threshold amounts by no more than about 50%.

24. An apparatus to treat an eye, the apparatus comprising:

a pulsed laser to generate pulses of light energy;

an optical delivery system coupled to the laser;

a processor coupled to the laser and the optical delivery system, the processor configured to generate a treatment table comprising a plurality of target locations of the eye and adjust the laser beam pulse energy at the plurality of target locations in response to the plurality of threshold amounts.

25. The apparatus of claim 24, wherein the processor is configured to determine a plurality of threshold amounts of laser beam energy to induce optical breakdown at a plurality of laser beam focus locations.

26. A method of treating an eye with a laser, the method comprising.

determining a threshold amount of an output pulse energy of the laser to provide optical breakdown within the eye;

and

adjusting the output pulse energy of the laser below threshold amount; and

providing optical breakdown within the eye with output pulse energy adjusted below the threshold amount.

27. An apparatus to treat an eye, the apparatus comprising:

a laser to generate a plurality of laser beam pulses;

an optical delivery system to deliver the plurality of laser beam pulses to a plurality of locations of the eye;

a processor coupled to the laser and the optical delivery system, the processor configured to determine a threshold amount of an output pulse energy of the laser to provide optical breakdown within the eye and adjust the output pulse energy of the laser below threshold amount in order to provide optical breakdown within the eye.

28. An apparatus to treat an eye, the apparatus comprising:

a laser to generate a plurality of laser beam pulses;

an optical delivery system comprising a movable lens to focus the plurality of laser beam pulses to a plurality of depth locations of the eye;

a patient interface to couple the optical delivery system to the eye, the patient interface comprising an interface lens having an anterior surface and a convexly curved posterior surface; and

a processor configured to adjust the movable lens to maintain focus of the laser beam pulses based on a measured location of the interface lens and mapped locations of the eye.

29. The apparatus of claim 28, wherein the processor is configured to determine a plurality of threshold amounts of laser beam energy to induce optical breakdown at a plurality of laser beam focus locations.