Valve Prosthesis Frames

• US 20140142693A1
• Filed: 11/20/2012
• Published: 05/22/2014
• Est. Priority Date: 11/20/2012
• Status: Abandoned Application

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Punga, Karan, Rinne, Finn, Krivoruchko, Michael
• Application Number:
  US13/681,594
• Publication Number:
  US 20140142693A1
• Time in Patent Office: Days
• US Class Current: 623/2.18
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0036 differing in thickness

Abstract

A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.

Claims

1. A prosthesis comprising:

a collapsible and reexpandable frame, the frame having a longitudinal axis, the frame comprising;

first, second, and third sets of struts;

wherein the first and second sets of struts are connected at a first plurality of nodes to define a first row of expandable cells;

wherein the second and third sets of struts are connected at a second plurality of nodes to define a second row of expandable cells, the first row of expandable cells being proximal to the second row of expandable cells;

wherein each strut of the first set of struts comprises a first proximal segment with a first width, a first intermediate segment with a second width, and a first distal segment with a third width;

wherein each strut of the second set of struts comprises a second proximal segment with a fourth width, a second intermediate segment with a fifth width, and a second distal segment with a sixth width;

wherein each strut of the third set of struts comprises a third proximal segment with a seventh width, a third intermediate segment with an eighth width, and a third distal segment with a ninth width;

wherein the second width is smaller than each of the first and third widths;

wherein the fifth width is smaller than each of the fourth and sixth widths; and

wherein the eighth width is smaller than each of the seventh and ninth widths.

2. The prosthesis of claim 1, wherein:

the first width is about equal to the third width;

the fourth width is about equal to the sixth width; and

the seventh width is about equal to the ninth width.

3. The prosthesis of claim 1, wherein the second width, the fifth width, and the eighth width are about 42% to about 50% smaller than each of the first and third widths, each of the fourth and sixths widths, and each of the seventh and ninth widths, respectively.

4. The prosthesis of claim 1, wherein:

the first, third, fourth, sixth, seventh, and ninth widths each have a dimension within a range from about 0.1 mm to about 1.2 mm; and

the second, fifth, and eighth widths each have a dimension within a range from about 0.05 mm to about 1.0 mm.

5. The prosthesis of claim 1, wherein:

each of node of the first plurality of nodes comprises a first curved section having a first radius, the first curved section defining a portion of a respective cell of the second row of expandable cells, and the first radius ranging from about 0.03 mm to about 0.1 mm;

each of node of the second plurality of nodes comprises a second curved section having a second radius, the second curved section defining a portion of a respective cell of the first row of expandable cells, and the second radius ranging from about 0.03 mm to about 0.1 mm.

6. The prosthesis of claim 1, wherein:

each node of the first plurality of nodes having a tenth width, the tenth width ranging from about 0.1 mm to about 5 mm; and

each node of the second plurality of nodes having an eleventh width, the eleventh width ranging from about 0.1 mm to about 5 mm.

7. The prosthesis of claim 1, wherein:

the frame includes an outflow section, an intermediate section proximal to the outflow section, and an inflow section proximal to the intermediate section; and

the first and second rows of expandable cells form a portion of the intermediate section.

8. The prosthesis of claim 1, further comprising a valve body coupled to the frame.

9. A prosthesis comprising:

a collapsible and reexpandable frame, the frame having a longitudinal axis, the frame comprising;

an intermediate section; and

an inflow section that is proximal to the intermediate section, the inflow section comprising;

a concave saddle portion that is adjacent the intermediate section, and

an outwardly flared portion.

10. The prosthesis of claim 9, wherein the concave saddle portion comprises first and second sets of struts defining only a single row of expandable cells.

11. The prosthesis of claim 10, wherein the first set of struts are connected to the second set of struts at a plurality of nodes, wherein a first outer diameter of the frame at the plurality of nodes is smaller than a second outer diameter of the frame at a boundary between the saddle portion and the intermediate section, and wherein the first outer diameter is smaller than a third outer diameter at a boundary between the saddle portion and the outwardly flared portion of the inflow section.

12. The prosthesis of claim 9, wherein a contour of the concave saddle portion forms a smooth curve.

13. The prosthesis of claim 9, wherein the outwardly flared portion is convex, and wherein a contour of the outwardly flared portion section forms a smooth curve.

14. The prosthesis of claim 9, wherein a longitudinal length of the inflow section ranges from about 2.0 mm to about 50 mm.

15. The prosthesis of claim 9, wherein the frame further comprises an outflow section, the outflow section being distal to the intermediate section.

16. The prosthesis of claim 15, wherein the outflow section comprises a first portion that flares outwardly.

17. The prosthesis of claim 16, wherein the outflow section further comprises a second portion adjacent the intermediate section and proximal to the first portion of the outflow section, and wherein a contour of the second portion is substantially parallel with the longitudinal axis.

18. The prosthesis of claim 17, wherein:

the first portion of the outflow section comprises a plurality of V-shaped structures each comprising a first strut having a first end and a second end, and a second strut having a first end and a second end;

the second end of the first strut is connected to the second end of the adjacent second strut;

the first end of the first strut is connected to a first expandable cell;

the first end of the second strut is connected to a second expandable cell; and

a third expandable cell is between the first expandable cell and the second expandable cell.

19. The prosthesis of claim 16, further comprising a valve body;

wherein the valve body comprises a plurality of leaflets, adjoining leaflets being joined together at commissures; and

wherein the commissures are coupled to the first portion of the outflow section.

20. The prosthesis of claim 19, further comprising a valve body;

wherein the outflow section further comprises a second portion adjacent the intermediate section and proximal to the first portion of the outflow section;

wherein a contour of the second portion is substantially parallel with the longitudinal axis;

wherein the valve body comprises a plurality of leaflets, adjoining leaflets being joined together at commissures; and

wherein the commissures are coupled to the second portion of the outflow section.

21. The prosthesis of claim 16, wherein the first portion of the outflow section is convex.

22. The prosthesis of claim 9, further comprising a valve body;

wherein the frame has a longitudinal length;

wherein the valve body comprises a plurality of leaflets, adjoining leaflets being joined together at commissures; and

wherein the commissures are coupled to the outflow section such that a distance between the commissures and an outflow edge of the outflow section is about 20% to about 35% of the longitudinal length of the frame.