OXIDIZABLE SPECIES AS AN INTERNAL REFERENCE IN CONTROL SOLUTIONS FOR BIOSENSORS
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Accused Products
Abstract
Testing of the performance of an electrochemical meter used to measure the presence of an analyte in a biological sample, particularly glucose in whole blood, includes introducing a control solution containing a predetermined amount of the analyte and a predetermined amount of an internal reference compound. The internal reference compound is selected such that it is oxidized at a potential greater than that used to oxidize the analyte, thereby making it possible to distinguish the control solution from a biological sample.
6 Citations
62 Claims
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1-37. -37. (canceled)
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38. A control solution for use in testing an electrochemical system for measuring the amount of an analyte in a sample, the control solution comprising:
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(a) a predetermined amount of the analyte; and (b) a predetermined amount of an internal reference compound, the internal reference compound having a redox potential that is at least 100 mV higher than the potential required to measure oxidation of the analyte. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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51. A control solution for use in testing an electrochemical system for measuring the amount of glucose in a whole blood sample, the control solution comprising:
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a predetermined amount of glucose; a predetermined amount of an internal reference compound, the internal reference compound having a redox potential that is at least 100 mV higher than the potential required to measure oxidation of the analyte, the internal reference compound being used to distinguish the control solution from the sample; and a buffer to assist in assuring that oxidizing the glucose. - View Dependent Claims (52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62)
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Specification