SYSTEMS, DEVICES, METHODS FOR DELIVERING HYDROGEL COMPOSITIONS WITH SELF-PURGING TO PREVENT CLOGGING

• US 20140148791A1
• Filed: 02/03/2014
• Published: 05/29/2014
• Est. Priority Date: 04/05/2010
• Status: Active Grant

• Current Assignee: Neomend, Inc. (Becton, Dickinson & Co)
• Original Assignee: Neomend, Inc. (Becton, Dickinson & Co)
• Inventors: MEZGER, William Jerome, BARKER, Peter Jr.
• Granted Patent: US 9,662,098 B2
• Time in Patent Office: Days
• US Class Current: 604/518
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: A61B 2017/00942 hydrophilic
• CPC Class Codes: A61M 35/003 Portable hand-held applicators having means for dispensing or spreading integral media hand-held massage devices with liquid delivery A61H7/003
• CPC Class Codes: A61M 5/003 Kits for diabetics

Abstract

A hydrogel composition is formed by conveying separate first and second liquid components subject to a selectively applied application pressure P(A) into an outlet path for mixing and discharge. A liquid flushing agent is automatically conveyed into the outlet path subject to a substantially constantly applied purge pressure P(P) when the application of P(A) is interrupted, to continuously flush residual hydrogel composition from the outlet path.

Claims

1. A self-purging system for delivering a hydrogel composition formed by mixing first and second liquid components comprising,

an applicator sized and configured to mix the first and second liquid components and form the hydrogel composition, the applicator including inlet paths that convey the first and second liquid components subject to a selectively applied application pressure P(A) into an outlet path for mixing and formation of the hydrogel composition for discharge from the outlet path, and

a purge assembly comprising a source of liquid flushing agent subject to a substantially constantly applied purge pressure P(P) that is maintained at a magnitude that is less than P(A), and a purging path coupling the source to the outlet path to convey liquid flushing agent into the outlet path subject to the substantially constantly applied purge pressure P(P), the purge assembly further including a valve assembly communicating with the purging path and the outlet path being operable in response to localized pressure conditions in first and second flow conditions, the first flow condition permitting the flow and mixing of the first and second liquid components but not the liquid flushing agent in the outlet path during the application of P(A), for dispensing the hydrogel composition from the outlet path, the second flow condition permitting the flow of liquid flushing agent but not the first and second liquid components in the outlet path subject to the substantially constantly applied purge pressure P(P), for continuously flushing residual hydrogel composition from the outlet path, the valve assembly being automatically placed in the first flow condition in response to localized pressure conditions whenever P(A) is applied, the valve assembly being automatically placed in the second flow condition in response to localized pressure conditions during an interruption of the application of P(A).

2. A system according to claim 1,

wherein the valve assembly includes a first valve element between the source and the outlet path operable in response to localized pressure conditions within the purging path between a closed condition and an opened condition, in the closed condition, the first valve element preventing pressurized flow of the liquid flushing agent through the purging path, in the opened condition, the first valve element allowing pressured flow of the liquid flushing agent through the purging path, the first valve element being sized and configured to assume the closed condition when pressure conditions in the purging path downstream of the first valve element exceed the pressure conditions in the purging path upstream of the first valve element.

3. A system according to claim 1,

wherein the valve assembly includes second and third valve elements in the inlet paths of the applicator upstream of the outlet path, each second and third valve element operating in response to localized pressure conditions within the respective inlet path between a closed condition and an opened condition, in the closed condition, each second and third valve element preventing the flow of liquid through the respective inlet path away from the outlet path, in the opened condition, each second and third valve element allowing the flow of liquid through the respective inlet path toward the outlet path, each second and third valve element being sized and configured to assume the closed condition when pressure conditions upstream of the first and second valve elements are less than the pressure conditions in the respective inlet path downstream of the second and third valve elements.

4. A system according to claim 1,

wherein the valve assembly includes a first one-way valve element in the purging path downstream of the source, and second and third one-way valve elements in the inlet path for the first component and second component, respectively, upstream of the outlet path.

5. A system according to claim 1,

wherein the purge assembly includes a manually operable control element to selectively enable and disable operation of the purge assembly.

6. A system according to claim 5,

wherein the control element includes a valve in the purging path manually operable between a closed condition disabling operation of the purge assembly and an opened condition enabling operation of the purge assembly.

7. A system according to claim 1,

wherein the source comprises a vessel, and wherein the substantially constantly applied purge pressure P(P) comprises operation of a spring biased piston within the vessel.

8. A system according to claim 1,

wherein the source comprises a vessel, and wherein the substantially constantly applied purge pressure P(P) comprises pneumatic pressure within the vessel.

9. A method for delivering a hydrogel composition comprising,

forming the hydrogel composition by conveying separate first and second liquid components subject to a selectively applied application pressure P(A) into an outlet path for mixing,

discharging the hydrogel composition from the outlet path by the application of the pressure P(A), and

coupling to the outlet path a source of liquid flushing agent subject to a substantially constantly applied purge pressure P(P) that is maintained at a magnitude that is less than P(A),

establishing, in response to localized pressure conditions when P(A) is applied, a first flow condition permitting the flow and mixing of the first and second liquid components in the outlet path, while simultaneously blocking the flow of liquid flushing agent in the outlet path, for dispensing the hydrogel composition from the outlet path, and

establishing, in response to localized pressure conditions when the application of P(A) is interrupted, a second flow condition permitting the flow of liquid flushing agent in the outlet path subject to the substantially constantly applied purge pressure P(P), while simultaneously blocking the flow of first and second liquid components into the outlet path, to continuously flush residual hydrogel composition from the outlet path during an interruption of P(A).

10. A method according to claim 9,

further including selectively enabling or disabling the establishment of the second flow condition.