METHOD AND DEVICE FOR MEASURING HEMATOCRIT

• US 20140166503A1
• Filed: 12/13/2012
• Published: 06/19/2014
• Est. Priority Date: 12/13/2012
• Status: Abandoned Application

• Current Assignee: Broadmaster Biotech Corp.
• Original Assignee: Broadmaster Biotech Corp.
• Inventors: Lai, Yao-Chun, Chen, Yi-Lung, Lai, Chien-Hung, Lin, Po-Hao, Lin, Ya-Sian, Lu, Shih-Jen, Liu, Chih-Wei
• Application Number:
  US13/712,987
• Publication Number:
  US 20140166503A1
• Time in Patent Office: Days
• US Class Current: 205/782
• CPC Class Codes: G01N 27/3275 Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction

Abstract

An approach is provided for a method and device for measuring Hematocrit (Hct) are disclosed that measures current variations from reactions of Electrochemistry on the electrodes. The method comprises acts of giving a blood sample on a pair of electrodes, obtaining a response current by providing a voltage on the electrodes, and determining an Hct value from the obtained current based on a predetermined rule. Therefore, the present disclosure provides higher reliable and precise measurement compared to the conventional measuring apparatus.

Claims

1. A method for measuring a hematocrit comprising steps of:

adding a blood sample on a pair of detecting electrode;

obtaining a response current by providing a voltage to the pair of detecting electrode; and

obtaining a hematocrit value according to a predetermined rule and the response current.

2. The method as claimed in claim 1, wherein the blood sample being added to the pair of detecting electrode spread with a surfactant.

3. The method as claimed in claim 2, wherein the surfactant being selected from the group consists of cetyltrimethylammonium bromide (CTAB)—

Triton X-100, TWEEN 20, TWEEN 40, TWEEN 60, Span 20, Carboxymethyl cellulose (CMC), sodium cholate and Sodium Dodecyl Sulphate (SDS).

4. The method as claimed in claim 1, wherein the voltage being inputted into the pair of detecting electrodes is between 1 and 3 volts.

5. A device for measuring a hematocrit comprising:

a detector comprising a pair of detecting electrode having a receiving portion and a contacting portion, wherein the receiver is used for accepting a blood sample; and

a measuring apparatus connecting to the contacting portion of the detector, and providing a voltage to the contactor based on a predetermined rule to obtain a hematocrit.

6. The device as claimed in the claim 5, wherein the measuring apparatus further comprises:

a pair of connector, each connector has a first terminal that is configured for connecting to the contacting portion of the detector;

a reference voltage source provides the voltage, and connects to a second terminal of one of the connecter to provide the voltage; and

a controller connects to a second terminal of another connecter and reference voltage source , and is configured for obtaining the hematocrit of the blood sample.

7. The device as claimed in the claim 6, wherein the detector further comprises:

a substrate is configured for disposing the detecting electrode thereon;

an insulating piece comprises a opening, is disposed on the substrate, partially covers above the detecting electrodes for a exposed portion at rear ends of the detecting electrodes being , wherein the opening is placed at a front end of the insulating piece for a exposed portion at front end of the detecting electrode; and

a cover is disposed on the insulating piece and comprises;

a conductive concave formed on a front end of the cover is overlapped corresponding to the opening of the insulating piece; and

a conductive hole formed on the cover corresponding to the opening of the insulating piece that form a pathway.

8. The device as claimed in the claim 7, wherein the substrate is made of non-conductive material selected from the group consists of:

polyethylene terephthalate (PET), Polyvinylchloride (PVC), Flame Resistant glass fiber (FR-4), phosphatidylcholine (PC). Polyethylene (PE), Polypropylene (PP), Polystyrene (PS), Polyester sulphone, ceramic plate (CEM) and glass.

9. The device as claimed in the claim 5, wherein the detector comprises a surfactant coves above the receiving portion of the pair of the detecting electrode.

10. The device as claimed in claim 9, wherein the surfactant being selected from the group consists of cetyltrimethylammonium bromide (CTAB)—

Triton X-100, TWEEN 20, TWEEN 40, TWEEN 60, Span 20, Carboxymethyl cellulose (CMC), sodium cholate and Sodium Dodecyl Sulphate (SDS).

11. The device as claimed in claim 5, wherein the voltage for detecting electrodes is provided in an range between 1 and 3 volts.