METHOD AND SYSTEM FOR A HYBRID CONTROL-TO-TARGET AND CONTROL-TO-RANGE MODEL PREDICTIVE CONTROL OF AN ARTIFICIAL PANCREAS
First Claim
1. A method to control an infusion pump with a model-predictive-controller and receive data from at least one glucose sensor, the method comprising:
- measuring glucose level in the subject from the glucose sensor to provide at least one glucose measurement in each time interval in a series of discrete time interval index (“
k”
);
predicting at least one future glucose value based on the glucose measurements made in the measuring step;
evaluating whether the at least one future glucose value is within a predetermined range of glucose values;
in the event the at least one future glucose value is not within the range, determining an insulin amount with the model-predictive controller based on a target value otherwise determining an insulin amount with the model-predictive-controller based on the predetermined range; and
delivering the insulin in the amount determined in the determining step.
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Accused Products
Abstract
Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed into the controller. The infusion pump is configured to deliver insulin to a subject. The glucose sensor is configured to sense glucose levels in the subject and provide output signals representative of the glucose levels in the subject. The controller is programmed to switchover from one mode of MPC control based on a predetermined range of blood glucose values to another MPC mode based on a predetermined target.
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Citations
4 Claims
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1. A method to control an infusion pump with a model-predictive-controller and receive data from at least one glucose sensor, the method comprising:
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measuring glucose level in the subject from the glucose sensor to provide at least one glucose measurement in each time interval in a series of discrete time interval index (“
k”
);predicting at least one future glucose value based on the glucose measurements made in the measuring step; evaluating whether the at least one future glucose value is within a predetermined range of glucose values; in the event the at least one future glucose value is not within the range, determining an insulin amount with the model-predictive controller based on a target value otherwise determining an insulin amount with the model-predictive-controller based on the predetermined range; and delivering the insulin in the amount determined in the determining step. - View Dependent Claims (2, 3)
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4. A system for management of diabetes comprising:
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a continuous glucose monitor to continuously measure glucose level of the subject at discrete generally uniform time intervals and provide the glucose level at each interval in the form of glucose measurement data; an insulin infusion pump to deliver insulin; and a controller in communication with the pump, glucose meter and the glucose monitor in which the controller is configured to predict at least one future glucose value based on prior glucose measurement data from the continuous glucose monitor, and evaluate whether the at least one future glucose value is within a predetermined range of glucose values and in the event the at least one future glucose value is not within the range, a determination is made of an insulin amount with the model-predictive controller based on a target value otherwise a determination is made of an insulin amount with the model-predictive-controller based on the predetermined range and command the insulin infusion pump to deliver the insulin amount determined by the controller.
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Specification