DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY

• US 20140188048A1
• Filed: 12/16/2013
• Published: 07/03/2014
• Est. Priority Date: 11/22/2004
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Intelliject Incorporated
• Inventors: EDWARDS, Eric S., EDWARDS, Evan T., LICATA, Mark J., MEYERS, Paul F.
• Granted Patent: US 9,056,170 B2
• Time in Patent Office: Days
• US Class Current: 604/140
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 2205/6036 characterised by physical shape, e.g. array of activating switches
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2046 Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2459 upon internal pressure increase, e.g. pierced or burst A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/31565 : Administration mechanisms, i.e. constructional features, modes of administering a dose dosing mechanisms for setting a dose A61M5/31533
• CPC Class Codes: A61M 5/31591 : Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
• CPC Class Codes: A61M 5/3202 : Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 : Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 : Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: B65B 3/003 : Filling medical containers such as ampoules, vials, syringes or the like
• CPC Class Codes: B65B 55/02 : Sterilising, e.g. of complete packages
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 40/63 : for local operation

Abstract

An apparatus includes a housing, a needle, a first energy storage member and a second energy storage member. The needle is movably disposed within the housing and is configured to be to be placed in fluid communication with a medicament container. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The first energy storage member is disposed within the housing, and is configured to produce a first force when actuated. The second energy storage member is disposed within the housing, and is configured to be actuated in response to the first force to produce a second force to move the needle from the first needle position to the second needle position.

Claims

1. An apparatus, comprising:

a housing;

a medicament injector movably disposed within the housing, the medicament injector including a medicament container and a needle;

an energy storage member configured to produce a force to move the medicament injector to an injection position in which a portion of the needle is disposed outside of a distal end portion of the housing;

a first actuation member configured to actuate the energy storage member when moved within the housing between a first position and a second position, the first actuation member including a retention portion configured to engage a portion of the housing to limit movement of the first actuation member; and

a second actuation member coupled to the distal end portion of the housing, a portion of the second actuation member configured to engage the retention portion of the first actuation member to disengage the retention portion from the portion of the housing when the second actuation member is moved relative to the distal end portion of the housing.

2. The apparatus of claim 1, further comprising:

a biasing member coupled to the first actuation member and configured to urge the first actuation member towards the second position.

3. The apparatus of claim 1, further comprising:

a safety lock movably coupled to the distal end portion of the housing, the safety lock including a protrusion configured to extend through an opening defined by the second actuation member to engage a portion of the first actuation member.

4. The apparatus of claim 1, wherein:

the energy storage member is a gas container configured to produce the force when a pressurized gas container is released from the gas container; and

a longitudinal axis of the gas container is offset from a longitudinal axis of the medicament injector.

5. The apparatus of claim 1, wherein:

the first actuation member is configured to move within the housing in a first direction; and

the medicament injector is configured to move in a second direction opposite the first direction when the medicament injector is moved to the injection position.

6. The apparatus of claim 1, wherein the medicament container contains epinephrine.

7. A method comprising:

filling a container with medicament within a sterile environment;

removing the container from the sterile environment;

inserting a needle into a needle hub of the container after removing the container from the sterile environment;

installing a needle cover; and

sterilizing the needle after installing the needle cover.