SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT

• US 20140188072A1
• Filed: 11/20/2013
• Published: 07/03/2014
• Est. Priority Date: 01/12/2011
• Status: Active Grant

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Rinehart, Joseph B., Cannesson, Maxime
• Granted Patent: US 10,434,255 B2
• Time in Patent Office: Days
• US Class Current: 604/503
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/00 Measuring parameters of the user
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/16877 Adjusting flow; Devices for setting a flow rate
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients.

Claims

1-20. -20. (canceled)

21. A computer-implemented method for providing clinical decision support relating to the administration of fluid to a patient, the method comprising:

receiving input information relating to one or more physiologic processes of a patient;

determining, based at least in part upon the input information, a subgroup of bolus log entries associated with a current state of the patient; and

providing, using the processor, a fluid administration recommendation based at least in part upon log data included within the subgroup of bolus log entries.

22. A computer-implemented method for providing clinical decision support relating to the administration of fluid to a patient, the method comprising:

determining a first effect on a physiologic parameter of the patient associated with administration of a first fluid bolus to the patient;

storing, using a processor, first information relating to the first effect in a first bolus log entry;

determining a second effect on the physiologic parameter of the patient associated with administration of a second fluid bolus to the patient;

storing, using a processor, second information relating to the second effect in a second bolus log entry; and

providing, using the processor, a fluid administration recommendation based at least in part upon at least one of the first bolus log entry and the second bolus log entry.

23. A computer-implemented method for providing clinical decision support relating to the administration of fluid to a patient, the method comprising:

receiving bolus log information relating to one or more effects on a state of the patient associated with prior administration of fluid to the patient;

determining, using a processor and based upon the bolus log information, a predicted change in a physiologic parameter of the patient in response to the administration of a fluid bolus to the patient; and

providing, using the processor, a fluid administration recommendation based upon the predicted change.

24. A computer-implemented method for facilitating the administration of fluid to a patient, the method comprising:

receiving bolus log information relating to one or more effects on a state of the patient associated with prior administration of fluid to the patient;

determining, using a processor and based upon the bolus log information, a predicted change in a physiologic parameter of the patient in response to the administration of a fluid bolus to the patient; and

generating, using the processor, a fluid administration signal based upon the predicted change.