Elongated Lung Volume Reduction Devices, Methods, and Systems

• US 20140188246A1
• Filed: 12/19/2013
• Published: 07/03/2014
• Est. Priority Date: 09/12/2008
• Status: Active Grant

• Current Assignee: Ekos LLC (Boston Scientific Corporation)
• Original Assignee: PneumRx, Inc. (Boston Scientific Corporation)
• Inventors: Aronson, Nathan, Mathis, Mark L.
• Granted Patent: US 9,192,403 B2
• Time in Patent Office: Days
• US Class Current: 623/23.65
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12131 characterised by the type of occluding device
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1285 for minimally invasive surgery
• CPC Class Codes: A61B 17/24 for use in the oral cavity, larynx, bronchial passages or nose for medical inspection of cavities or tubes in the body A61B1/00; Tongue scrapers
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2034/108 Computer aided selection or customisation of medical implants or cutting guides
• CPC Class Codes: A61B 2090/061 for measuring dimensions, e.g. length
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/091 Measuring volume of inspired or expired gases, e.g. to determine lung capacity
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 90/00 Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges protective face masks A41D13/11; surgeon's or patient's gowns or dresses A41D13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M1/00
• CPC Class Codes: A61M 16/04 : Tracheal tubes catheters in general A61M25/00
• CPC Class Codes: A61M 16/0406 : implanted flow modifiers
• CPC Class Codes: A61M 16/0833 : T- or Y-type connectors, e.g. Y-piece
• CPC Class Codes: A61M 2205/0266 : Shape memory materials

Abstract

A lung volume reduction system is disclosed comprising an elongate implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to compress lung tissue. The implant may be longer in axial length than an axial length of the target axial region in which it is deployed. Deployment may involve allowing an end of the implant to move relative to surrounding tissue while the implant is progressively deployed.

Claims

1. A method for treating a lung of a patient, the lung including an airway system having a plurality of branching airways, the method comprising:

advancing an implant through the airway system, the implant having an elongate length;

deploying a distal portion of the implant within the airway system so that the distal portion engages an airway; and

progressively deploying the implant proximally of the distal portion while a proximal end of the implant advances distally relative to the adjacent airway system so as to inhibit axial loading between the implant and the airway when the implant compresses lung tissue along the length of the implant.

2. The method of claim 1, further comprising deploying the distal portion of the implant near a surface of the lung, and wherein the proximal end of the implant is allowed to advance by at least 10% of the length of the implant so as to inhibit localized strain near the surface of the lung.

3. The method of claim 1, wherein the implant advances through a lumen of a bronchoscope during compression of the lung, and further comprising viewing the proximal end of the implant using the bronchoscope before mechanically decoupling the implant from the bronchoscope.

4. The method of claim 1, wherein implant comprises an elongate body, wherein the implant is advanced distally through a lumen of a delivery catheter, wherein the delivery catheter constrains the elongate body to a sufficiently straight configuration to allow the implant to be advanced axially within the airway, and wherein the implant is deployed by withdrawing the delivery catheter proximally from around the elongate body so that the elongate body is released to compress lung tissue between ends of the elongate body.

5. A system for treating a lung of a patient, the lung including an airway system having a plurality of branching airways, the system comprising:

a catheter having a proximal end and a distal end with a lumen therebetween, the distal end of the catheter advanceable through the airway system;

an implant receivable by the lumen, the implant comprising an elongate body having a distal portion and a proximal portion adjacent a proximal end of the implant, the distal portion biased so that retraction of the distal end of the catheter from the distal portion of the implant releases the distal portion to engage the airway, the proximal end of the implant advanceable distally relative to the airway while the catheter is withdrawn proximally from the proximal portion of the implant.

6. The system of claim 5, wherein the catheter comprises a bronchoscope.

7. The system of claim 5, wherein the implant has a length of over 110 mm.

8. The system of claim 7, wherein the implant has a length in a range from about 120 mm to about 250 mm.

9. An implant for treating a lung of a patient, the lung including an airway system having a plurality of branching airways, the implant comprising:

an elongate body advanceable through the airway system, the body having a proximal end and a distal end;

autramatic surfaces disposed adjacent the distal and proximal ends of the elongate body so as to engage the surrounding airway system and inhibit penetration through the airway system when the elongate body compresses lung tissue between the ends from within the airway, the implant having a length of over 110 mm between the atraumatic surfaces.

10. The system of claim 9, wherein the autramatic ends have of over about 1 mm.

11. The system of claim 9, wherein the implant has a length in a range from about 120 mm to about 250 mm.