SYSTEM AND METHOD FOR EVALUATING AN ELECTROPHYSIOLOGICAL SIGNAL
First Claim
1. A method of detecting an abnormality in a patient from an electrophysiological signal, comprising:
- a) obtaining an electrophysiological signal corresponding to the patient;
b) finding a model corresponding to the electrophysiological signal wherein at least one term in the model is differentiable;
c) obtaining the derivative of the at least one term; and
d) using the derivative over at least one cycle of the electrophysiological signal in order to detect the abnormality.
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Abstract
A method of evaluating an electrophysical signal. The method utilizes a model-derived reconstruction over at least one cycle of the electrophysical signal to identify a pathological event, whereby at least one term in the model is differentiable. The invention is also directed to a non-transitory computer readable medium having instructions stored thereon for identifying a pathological event from a model-derived reconstruction of an electrophysical signal. The invention is further directed to a system for evaluating an electrophysical signal. The system includes a processor configured to identify a pathological event from a model-derived reconstruction of the electrophysical signal, a data input coupled to the processor for providing the processor with the electrophysical signal, and a user interface.
22 Citations
20 Claims
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1. A method of detecting an abnormality in a patient from an electrophysiological signal, comprising:
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a) obtaining an electrophysiological signal corresponding to the patient; b) finding a model corresponding to the electrophysiological signal wherein at least one term in the model is differentiable; c) obtaining the derivative of the at least one term; and d) using the derivative over at least one cycle of the electrophysiological signal in order to detect the abnormality. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 13, 14, 15, 17, 18)
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9. A method for building a model approximating an electrophysiological signal, wherein the method includes choosing a measure of approximating the signal, wherein the method involves a search through candidate terms to select terms to add to the model at successive stages, and wherein at least two distinct candidate terms are selected at the same stage at least once, where one of the selected terms causes, out of the candidate terms searched, the greatest reduction in the measure of approximating the signal, and another of the selected terms causes, out of the candidate terms searched, at least one of:
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a relative maximum of the reduction of the measure of approximating the signal; and a reduction of the measure of approximating the signal above a specified threshold level. - View Dependent Claims (10, 11, 12, 16)
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19. A method of using a model-building procedure to select a concise subset of electrocardiogram (ECG) leads to use out of a larger set of ECG leads, comprising:
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a. for each lead in the larger set, using the corresponding lead signal to define a candidate signal; b. for each lead in the larger set, using the corresponding lead signal to define a desired target output signal from an experiment; and c. selecting the same subset of lead signals, out of the candidate signals, to approximate all the target signals from all the experiments by linear combinations of the selected lead signals, while allowing the coefficients of the selected lead signals to vary in approximating the target signals from one experiment to another. - View Dependent Claims (20)
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Specification