OSTEOGRAFT IMPLANT

• US 20140195005A1
• Filed: 01/08/2013
• Published: 07/10/2014
• Est. Priority Date: 01/08/2013
• Status: Active Grant

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Inventors: MCKAY, WILLIAM F.
• Granted Patent: US 9,265,609 B2
• Time in Patent Office: Days
• US Class Current: 623/23.63
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/2839 Bone plugs or bone graft dowels
• CPC Class Codes: A61F 2002/30059 differing in bone mineralization, e.g. made from both mineralized and demineralized adjacent parts
• CPC Class Codes: A61F 2002/30261 parallelepipedal
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2310/00179 Ceramics or ceramic-like structures
• CPC Class Codes: A61F 2310/00359 Bone or bony tissue
• CPC Class Codes: A61F 2310/00371 Collagen
• CPC Class Codes: A61L 2430/02 for reconstruction of bones; weight-bearing implants
• CPC Class Codes: A61L 27/3608 Bone, e.g. demineralised bone matrix [DBM], bone powder
• CPC Class Codes: A61L 27/50 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

Abstract

Bone implant compositions are provided that include a body made of cortical bone extending along an axis between a first end and a second end. The body includes an outer surface configured to engage host bone of a patient and at least one recess extending transverse to the axis into the outer surface of the body configured for disposal of an insert. At least one insert made of demineralized bone is disposed in the at least one recess.

Claims

1. An osteograft comprising:

a body comprising cortical bone extending along an axis between a first end and a second end and including an outer surface configured to engage host bone of a patient, the body including at least one recess extending transverse to the axis into the outer surface configured for disposal of an insert; and

at least one insert comprising demineralized bone disposed in the at least one recess.

2. An osteograft as recited in claim 1, wherein the at least one recess extends perpendicular to the axis.

3. An osteograft as recited in claim 1, wherein the at least one insert comprises a plug.

4. An osteograft as recited in claim 1, wherein the at least one insert comprises a strip.

5. An osteograft as recited in claim 1, wherein the at least one recess has a circular cross-sectional configuration and the at least one insert has a polygonal cross-sectional configuration.

6. An osteograft as recited in claim 1, wherein the at least one insert comprises whole or partially demineralized cortical or cancellous bone and has a maximum width that is greater than a maximum width of the at least one recess, and the at least one insert is movable between a first configuration in which the at least one insert deforms to facilitate insertion into the at least one recess and a second configuration in which the at least one insert expands to retain the at least one insert in the at least one recess.

7. An osteograft as recited in claim 1, wherein the at least one insert comprises cancellous bone and has a maximum width that is greater than a maximum width of the at least one recess, and the at least one insert is movable between a first configuration in which the at least one insert deforms to facilitate insertion into the at least one recess and a second configuration in which the at least one insert expands to retain the at least one insert in the at least one recess.

8. An osteograft as recited in claim 1, wherein the at least one insert is press fit into the at least one recess.

9. An osteograft as recited in claim 1, wherein at least a portion of the body is surface demineralized to promote chemical or cohesive bonding or mechanical press fit between the body and the at least one insert.

10. An osteograft as recited in claim 1, wherein the body comprises an allograft and the at least one insert comprises bone material obtained from the patient.

11. An osteograft as recited in claim 1, wherein the at least one recess comprises a plurality of recesses that are spaced apart from one another and the at least one insert comprises a plurality of inserts.

12. An osteograft as recited in claim 1, wherein the outer surface of the body comprises an upper surface and a lower surface opposite the upper surface, and the at least one recess comprises a plurality of spaced apart recesses in the upper surface and a plurality of spaced apart recesses in the lower surface.

13. An osteograft as recited in claim 1, wherein the outer surface of the body comprises an upper surface and a lower surface opposite the upper surface, and the at least one recess comprises a plurality of spaced apart recesses disposed circumferentially about the upper surface and a plurality of spaced apart recesses disposed circumferentially about the lower surface.

14. An osteograft as recited in claim 1, wherein the outer surface of the body comprises an upper surface and a lower surface opposite the upper surface, the at least one recess comprises a plurality of spaced apart recesses in the upper surface and a plurality of spaced apart recesses in the lower surface, and each of the recesses in the upper surface is coaxial with a respective recess in the lower surface.

15. An osteograft as recited in claim 1, wherein the body comprises an upper surface and a lower surface opposite the upper surface, the body includes an inner surface defining an opening extending through the upper and lower surfaces, and the at least one recess comprises a plurality of spaced apart recesses disposed about the upper surface, a plurality of spaced apart recesses disposed about the lower surface and a plurality of spaced apart recess disposed about the inner surface.

16. A kit comprising:

an osteograft having a body comprising cortical bone extending between a first end and a second end along an axis and including an outer surface configured to engage host bone of a patient, the body including upper and lower surfaces and an inner surface defining an opening extending through the upper and lower surfaces, the upper and lower surfaces each comprising a plurality of recesses extending transverse to the axis into the outer surface, the inner surface comprising a plurality of recesses extending parallel to the axis into the inner surface, the recesses each having a circular cross-sectional configuration;

a plurality of plugs comprising demineralized bone and having a polygonal cross-sectional configuration configured for disposal in one of the recesses; and

/or

a plurality of plugs comprising demineralized bone and having a circular cross-sectional configuration configured for disposal in one of the recesses.

18. An osteograft comprising:

a body comprising cortical bone extending between a first end and a second end along an axis and including an outer surface configured to engage host bone of a patient, the body comprising an upper surface and a lower surface opposite the upper surface, the body including an inner surface defining an opening extending through the upper and lower surfaces, the upper and lower surfaces each including a plurality of recesses each having a circular cross-sectional configuration and extending perpendicular to the axis into the outer surface disposed circumferentially about the upper and lower surfaces, the inner surface including a plurality of recesses each having a circular cross-sectional configuration and extending parallel to the axis; and

a plurality of plugs comprising demineralized bone each having a circular cross-sectional configuration disposed in one of the recesses,

wherein the inner and outer surfaces are surface demineralized before the plugs are disposed into the recesses to promote chemical or cohesive bonding or mechanical press fit between the body and the plugs.

17. A kit as recited in claim 18, wherein the recesses are uniform and each have a maximum width that is greater than a maximum with of the plugs having a circular cross-sectional configuration, the maximum width of the recesses being less than a maximum width of the plugs having a polygonal cross-sectional configuration.