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Saliva Glucose Monitoring System

  • US 20140197042A1
  • Filed: 01/13/2014
  • Published: 07/17/2014
  • Est. Priority Date: 01/11/2013
  • Status: Active Grant
First Claim
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1. A glucose sensor for determining a concentration of glucose in a liquid sample, the sensor comprising:

  • an insulating or semiconducting substrate;

    at least one working electrode, a counter electrode, and a reference electrode, anda sample placement area on a surface of the substrate for containing the liquid sample during a determination of the glucose concentration in the liquid sample;

    wherein each of the working electrode(s), counter electrode, and reference electrode comprises a conductive metal layer deposited on the substrate in the sample placement area;

    wherein the working electrode is optionally coated in the sample placement area with a plurality of sensor elements;

    wherein the sensor elements or the working electrode in the sample placement area is functionalized with a coating comprising glucose oxidase;

    wherein the working electrode, counter electrode, and reference electrode are connected to an amperometry circuit; and

    wherein an output voltage of the amperometry circuit correlates with a glucose concentration in the liquid sample deposited in the sample placement area.

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