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METHODS FOR TREATING CANCER USING ANTI-PD-1 ANTIBODIES IN COMBINATION WITH ANTI-CTLA-4 ANTIBODIES

  • US 20140212422A1
  • Filed: 03/27/2014
  • Published: 07/31/2014
  • Est. Priority Date: 05/09/2005
  • Status: Active Grant
First Claim
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1. A method for treating a cancer in a subject comprising administering to the subject a combination of an anti-PD-1 antibody, or an antigen-binding portion thereof, and an anti-CTLA-4 antibody, or an antigen-binding portion thereof, wherein the combination of the anti-PD-1 antibody or antigen-binding portion thereof and the anti-CTLA-4 antibody or antigen-binding portion thereof exhibits a synergistic therapeutic effect on cancer treatment.

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