HISTONE DEMETHYLASE INHIBITORS
First Claim
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1. A compound of Formula (XI), or a pharmaceutically acceptable salt thereof,
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Abstract
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
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Citations
21 Claims
- 1. A compound of Formula (XI), or a pharmaceutically acceptable salt thereof,
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2. A compound of Formula (XI), or a pharmaceutically acceptable salt thereof,
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3. A compound of Formula (XV), or a pharmaceutically acceptable salt thereof,
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8. (canceled)
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18. A compound, or a pharmaceutically acceptable salt thereof, selected from the group consisting of:
Specification