SYSTEM, METHOD AND DEVICE FOR AUTOMATIC NONINVASIVE SCREENING FOR DIABETES AND PRE-DIABETES
First Claim
Patent Images
1. A system for an automatic noninvasive screening for diabetes and pre-diabetes using at least one image, the system comprising:
- a) an imaging device for taking at least one image of a patient'"'"'s eye;
b) a processor, operably connected to the imaging device, comprising non-transitory instructions executable on the processor for analyzing the image; and
c) an indicator operably connected to the imaging device and the processor for displaying an indication if the patient has diabetes.
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Abstract
A system for an automatic noninvasive screening for diabetes and pre-diabetes using a device to take at least one image of a patient'"'"'s eye, executing non-transitory instructions executable on a processor for analyzing the image and displaying an indication if the patient has diabetes.
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Citations
49 Claims
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1. A system for an automatic noninvasive screening for diabetes and pre-diabetes using at least one image, the system comprising:
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a) an imaging device for taking at least one image of a patient'"'"'s eye; b) a processor, operably connected to the imaging device, comprising non-transitory instructions executable on the processor for analyzing the image; and c) an indicator operably connected to the imaging device and the processor for displaying an indication if the patient has diabetes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A device useful for a system for automatic noninvasive screening for diabetes and pre-diabetes, the device comprising:
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a) an eyepiece; b) a tube having a proximal and distal end and an exterior and interior portion, where the eyepiece is attached to the distal end; c) a light source affixed to the interior portion of the tube; d) a magnifying lens affixed to the interior portion near the proximal end of the tube; and e) a camera body affixed to the proximal end of the tube. - View Dependent Claims (18, 19, 20, 21, 22)
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23. A device useful for a system for automatic noninvasive screening for diabetes and pre-diabetes, the device comprising:
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a) a handheld computer; b) a camera body coupled to the handheld computer; and c) a lens with a light source wrapped around the lens coupled to the camera body, where the light source can direct light to the eye in a uniform, diffuse manner, as well as minimize reflected glare. - View Dependent Claims (24, 25, 26)
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27. A method for an automatic noninvasive screening for diabetes and pre-diabetes using at least one image, the method comprising the steps of:
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a) capturing a color image of a patient'"'"'s eye; b) storing the image in a storage for processing; c) converting the color image to a grayscale image; d) applying a box blur filter to the grayscale image; e) applying a noise reduction filter the box blur image; f) normalizing the noise reduced image; g) increasing the range between white (conjunctiva) and black (blood vessel) pixels on the normalized image; h) applying a Gaussian Matched filter to the range increased image; i) scoring each pixel of the Gaussian Matched image on a likelihood of being in a blood vessel; j) calculating, for each of the scored pixels, the best orthogonal angle; k) rank segmenting the results; i) identifying the best identified blood vessel candidates from the segmented rankings using a threshold; j) calculating a midpoint for each segment; k) calculating midpoints for the rank segmented pixels; m) calculating blood vessel diameters associated with each midpoint; n) chaining each identified midpoint to the other identified midpoints; o) calculating a line that connects and traverses the blood vessel through the chained midpoints creating a line; and p) performing feature analysis on the blood vessel using statistics and the blood vessel chains to identify and measure features in the micro circulation to identified diabetic conditions. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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Specification