PERIPHERAL SEALING VENOUS CHECK-VALVE

• US 20140228940A1
• Filed: 02/07/2014
• Published: 08/14/2014
• Est. Priority Date: 02/08/2013
• Status: Active Grant

• Current Assignee: Muffin Incorporated
• Original Assignee: Muffin Incorporated
• Inventors: McKinnis, Peter S., Fearnot, Neal E.
• Granted Patent: US 9,629,721 B2
• Time in Patent Office: Days
• US Class Current: 623/1.24
• CPC Class Codes: A61F 2/2415 Manufacturing methods
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2250/0037 differing in height or in length

Abstract

Among other things, there are disclosed embodiments of a valve implant that in particular examples are implantable within a blood vessel, which include a first set of elongate members, a second set of elongate members, and a hood affixed to the first set of elongate members. The first set of elongate members is resiliently deformable, and their distal ends are flared radially outward. The distal ends of the second set of elongate members are distal to the ends of the first set of elongate members. The hood is affixed to the first set of elongate members, and seals against the interior wall of the blood vessel in an expanded configuration. When blood flows from the proximal to the distal side of the valve implant, it presses on the hood, compressing the first set of elongate members, breaking the seal.

Claims

1. A valve implant for implantation in a bodily lumen, the implant having a central axis, a proximal end, and a distal end, the implant comprising:

a first set of resiliently deformable, elongate members, each having respective proximal and distal ends, the proximal ends adjacent to one another, and respective distal ends flared radially outward;

a second set of elongate members, each having respective proximal and distal ends, the proximal ends adjacent to the proximal ends of the first set of elongate members, and the distal ends both flared radially outward and distal to the distal ends of the first set of elongate members;

a substantially fluid-tight hood affixed to the first set of elongate members, the hood and first set of elongate members forming a concavity;

wherein at least part of the hood is collapsible toward the central axis when blood flows in a direction generally from the proximal end to the distal end, thereby allowing blood to flow past the vascular implant.

2. The valve implant of claim 1, further comprising a collar that affixes the distal ends of at least one of the sets of the elongate members to one another.

3. The valve implant of claim 1, wherein the elongate members are made from a biocompatible material.

4. The valve implant of claim 1, wherein at least one of the elongate members are made from an echogenic material.

5. The valve implant of claim 1, wherein torsion springs are affixed to the distal ends of the second set of elongate members.

6. The valve implant of claim 1, wherein the distal ends of the second set of elongate members form torsion springs.

7. The valve implant of claim 1, wherein at least one of the elongate members are wires.

8. The valve implant of claim 1, wherein the hood comprises extracellular matrix.

11. The valve implant of claim 1, wherein the valve implant is sized and configured for placement in a blood vessel.

10. The valve implant of claim 10, further comprising a basement membrane, the endothelial colony forming cells being implanted on the basement membrane.

9. The valve implant of claim 10, wherein the hood comprises endothelial colony forming cells.

12. A valve implant for placement within a patient, comprising:

a set of resiliently deformable struts, the struts each having respective proximal and distal ends and a middle portion, the middle portions and distal ends of the struts flaring outward with respect to each other so that the struts together have a generally bulbous aspect, wherein the struts have a first open configuration toward which the struts are biased and are resiliently bendable to a second configuration in which the distal ends of one or more of the struts are closer to each other than they are in the open configuration;

a substantially fluid-tight hood affixed to a plurality of the struts, the hood forming a concavity having a mouth with a first width when the struts are in the open configuration and a second smaller width when the struts are in the second configuration, and the hood having an exterior surface opposite the concavity; and

a set of elongated legs each having respective proximal and distal ends, the distal ends of the elongated legs being flared radially outward and being further from the proximal ends of the struts than the distal ends of the struts are from the proximal ends of the struts.

13. The implant of claim 12, wherein the implant is for implantation in a blood vessel, and wherein the struts have a spring constant such that when flow in the blood vessel normal for the patient presses on the exterior surface of the hood when the struts are in the open configuration, the struts and hood compress toward the second configuration and allows flow past the hood.

14. The implant of claim 13, wherein the distal end of at least one leg includes a foot that engages the inside of the vessel.

15. The implant of claim 14, wherein the foot includes a torsion spring.

16. The implant of claim 12, wherein the hood comprises an easily endothelializable material.

17. The implant of claim 16, wherein the material is a collagenous material.

18. The implant of claim 12, wherein the proximal ends of the struts are adjacent and fixed to each other.

19. The implant of claim 12, wherein the proximal ends of the legs are adjacent and fixed to each other.