SOLID, EDIBLE, CHEWABLE LAXATIVE COMPOSITION

• US 20140235730A1
• Filed: 09/21/2012
• Published: 08/21/2014
• Est. Priority Date: 09/23/2011
• Status: Abandoned Application

• Current Assignee: Lupin Atlantis Holdings SA (Lupin Limited)
• Original Assignee: Gavis Pharma LLC (Lupin Limited)
• Inventors: Subramanian, Veerappan Sellappan, Kanni, Paranjothy, Vangala, Shyam Sundar Kumar Sarma
• Application Number:
  US14/346,668
• Publication Number:
  US 20140235730A1
• Time in Patent Office: Days
• US Class Current: 514/723
• CPC Class Codes: A23G 1/32 characterised by the composition containing organic or inorganic compounds
• CPC Class Codes: A23G 3/36 characterised by the composition containing organic or inorganic compounds
• CPC Class Codes: A23G 3/364 containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
• CPC Class Codes: A23L 29/37 Sugar alcohols
• CPC Class Codes: A23L 33/10 using additives addition of substantially indigestible substances A23L33/21
• CPC Class Codes: A23L 33/16 Inorganic salts, minerals or trace elements
• CPC Class Codes: A23L 33/21 Addition of substantially indigestible substances, e.g. dietary fibres
• CPC Class Codes: A61K 31/08 acyclic, e.g. paraformaldehyde
• CPC Class Codes: A61K 31/765 Polymers containing oxygen
• CPC Class Codes: A61K 31/77 of oxiranes
• CPC Class Codes: A61K 33/00 Medicinal preparations containing inorganic active ingredients
• CPC Class Codes: A61K 9/0056 Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Abstract

The invention is directed to an edible solid composition having laxative properties. The composition has a smooth mouth feel, in non-gritty and has a pleasant taste. It is prepared by melt-combining together the ingredients including a bulking agent and laxative as well as an optional flavor agent and electrolyte. The melt is a dispersion containing a substantially homogeneous combination of ingredients. The melt is cooled to form an amorphous solid dispersion or solution of the ingredients. The ingredients are mutually compatible so that upon cooling they do not separately crystallize to form a gritty mouth feel product.

Claims

1. An edible, solid composition, comprising:

a laxative and a bulking agent wherein the composition is formed by heating the laxative and bulking agent together to form a fluid dispersion and cooling the fluid dispersion to form the edible solid composition, and wherein the edible solid composition has laxative properties.

2. The edible, solid composition according to claim 1 wherein the bulking agent is selected from the group consisting of corn syrup, sorbitol, sucrose, dextrose, invert sugar, ludiflash, chocolate, maltitol, high fructose syrup, rice syrup, barley malt syrup, glycerin, maltodextrins, starch hydrolysate, honey, molasses, soy lecithin, condensed milk, fat free sweetened condensed milk, evaporated milk, sweetened condensed milk and any combination thereof.

3. The edible, solid composition according to claim 1 further comprising a sweetening agent.

4. The edible, solid composition according to claim 3 wherein the sweetening agent is selected from the group consisting of sugar, sorbitol, saccharine, aspartame, acesulfame potassium, sucralose, isomalt, mannitol, stevia, cyclamate, dextrose, glucose, fructose, honey, high fructose syrup and any combination thereof.

5. The edible, solid composition according to claim 1 wherein the laxative is selected from the group consisting of polyethylene glycol, castor oil, senna, bisacodyl, sodium pico sulfate, magnesium citrate, magnesium hydroxide (milk of magnesia), magnesium carbonate magnesium sulfate (Epsom salt), sodium sulfate, potassium sulfate, sodium chloride, potassium chloride, sodium bicarbonate, aloes, cascara sacrada, psyllium husk (Metamusil), guar gum, maltodextrins, inulin, docusate sodium, methyl cellulose, monobasic sodium phosphate, dibasic sodium phosphate, glycerin, sorbitol, mannitol, sodium potassium tartrate, mineral oil (liquid paraffin), lactulose, rhubarb, agar agar, figs (Syrup of Figs), L-glucose and any combination thereof.

6. The edible, solid composition according to claim 5 wherein the laxative is polyethylene glycol, magnesium citrate, inulin, castor oil or lactulose.

7. The edible, solid composition according to claim 1 wherein the laxative comprises at least 40 wt % relative to the total weight of the composition.

8. The edible, solid composition according to claim 1 wherein the laxative is polyethylene glycol and the polyethylene glycol is melted or its physical form is converted to a flowable viscosity by application of heat.

9. The edible, solid composition according to claim 8 wherein the bulking agent is mixed with the melted or flowably viscous polyethylene glycol to form a flowable dispersion of ingredients and the flowable dispersion is placed into one or more molds and cooled to form the solid composition.

10. The edible, solid composition according to claim 1 in the form of a bar, a lozenge, a chewable candy, or a chewable solid confection.

11. The edible, solid composition according to claim 10 wherein the form is substantially homogeneous.

12. The edible, solid composition according to claim 11 which remains solid at ambient temperature.

13. The edible, solid composition according to claim 10 wherein the bulking agent is selected from the group consisting of soy lecithin, condensed milk, fat free sweetened condensed milk, evaporated milk, sweetened condensed milk and any combination thereof;

and the laxative is selected from the group consisting of polyethylene glycol, magnesium citrate, lactulose and any combination thereof; and

the composition is in the solid form of a bar or chewable candy.

14. The edible, solid composition according to claim 13 wherein the bulking agent is a combination of soy lecithin and a second bulking agent selected from the group consisting of condensed milk, fat free sweetened condensed milk, evaporated milk, sweetened condensed milk and any combination thereof;

the laxative is polyethylene glycol; and

the composition is in the solid form of a bar or chewable candy.

15. The edible, solid composition according to claim 1 further comprising an electrolyte.

16. The edible, solid composition according to claim 1 further comprising a flavoring agent.

17. The edible, solid composition according to claim 15 wherein the electrolyte is selected from the group consisting of sodium chloride, potassium chloride, potassium bicarbonate, magnesium chloride and any combination thereof.

18. The edible, solid composition according to claim 16 wherein the flavoring agent is selected from the group consisting of bubble gum, cherry, mixed berry, fruit punch, pine apple, caramel, mixed fruit, chocolate, spearmint, peppermint, menthol, licorice, orange, lemon, Watermelon, melagawine, cranberry, tutti frutti, mix of cardamom and orange, vanilla, ice cream soda, salt masking flavor and any combination thereof.

19. The edible, solid composition according to claim 1, wherein the laxative is polyethylene glycol is polyethylene glycol 3350.

20. The edible composition according to claim 1, wherein the bulking agents are less than 20% of the weight of the bar.

21. The edible, solid composition according to claim 1, wherein the bulking agents are less than 10% of the weight of the bar.

22. An edible solid composition comprising a substantially homogeneous, solid, amorphous dispersion of a laxative, a bulking agent and a sweeting agent, the dispersion having a smooth, non-crystalline, non-gritty mouth feel and a sweet taste.

23. The edible solid composition according to claim 22 wherein the laxative is polyethylene glycol, magnesium citrate, inulin, castor oil or lactulose.

24. The edible solid composition according to claim 22 wherein the laxative is polyethylene glycol.

25. The edible solid composition according to claim 22 containing chocolate.