DEVICES, SYSTEMS AND METHODS FOR LOCATING AND INTERACTING WITH MEDICAMENT DELIVERY SYSTEMS

• US 20140243749A1
• Filed: 12/27/2013
• Published: 08/28/2014
• Est. Priority Date: 12/27/2012
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Intelliject Incorporated
• Inventors: EDWARDS, Eric S., EDWARDS, Evan T., LICATA, Mark J., MEYERS, Paul F., KAMAT, Vaishali, Gardner, Steven David, Milner, Robert George
• Granted Patent: US 9,911,308 B2
• Time in Patent Office: Days
• US Class Current: 604/187
• CPC Class Codes: A61M 11/007 Syringe-type or piston-type sprayers or atomisers
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0001 Details of inhalators; Constructional features thereof
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/43 making noise when used correctly
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 : by visual feedback
• CPC Class Codes: A61M 2205/587 : Lighting arrangements
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2205/8212 : with means or measures taken for minimising energy consumption
• CPC Class Codes: A61M 2230/04 : Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/20 : Blood composition characteristics
• CPC Class Codes: A61M 2230/201 : Glucose concentration
• CPC Class Codes: A61M 2230/42 : Rate
• CPC Class Codes: A61M 5/20 : Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2053 : Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/31 : Details
• CPC Class Codes: A61M 5/3157 : Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/3202 : Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/5086 : for indicating if defective, used, tampered with or unsterile
• CPC Class Codes: G08B 21/185 : Electrical failure alarms
• CPC Class Codes: G09B 9/00 : Simulators for teaching or training purposes for the use of weapons F41; computing aspects G06; protocols for games, networked simulations or virtual reality H04L67/131
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: H04B 1/3827 : Portable transceivers
• CPC Class Codes: H04W 4/80 : Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

In some embodiments, a method includes producing, from an adapter, a first wireless signal characterized by a first communication mode with a computing device when a portion of at least one of a medicament delivery device or a simulated medicament delivery is disposed within the adapter. An indication is received when the portion of the medicament delivery device or the simulated medicament delivery device is removed from the adapter. A second wireless signal characterized by a second communication mode with the computing device is produced in response to the indication. The second communication mode is different from the first communication mode. The second communication mode can be, for example, a hold mode, a sniff mode or a park mode.

Claims

1. An apparatus, comprising:

a medicament delivery device; and

an electronic circuit system including a radio configured to electronically communicate with a computing device via a wireless protocol, the radio configured to send a first signal characterized by a first communication interval when the medicament delivery device is in a first configuration, the radio configured to send a second signal characterized by a second communication interval when the medicament delivery device is in a second configuration, the second communication interval different from the first communication interval.

2. The apparatus of claim 1, wherein the second communication interval is at least one of an advertising interval, a hold duration period, a sniff interval or a park mode beacon period.

3. The apparatus of claim 1, wherein:

the first communication interval is associated with a first communication mode between the electronic circuit system and the computing device; and

the second communication interval is associated with a second communication mode between the electronic circuit system and the computing device, the second communication mode different than the first communication mode.

4. The apparatus of claim 1, wherein:

the first communication interval is associated with a communication latency between the electronic circuit system and the computing device of greater than about one second; and

the second communication interval is associated with a communication latency between the electronic circuit system and the computing device of less than about one second.

5. The apparatus of claim 1, wherein:

the electronic circuit system includes a sensor configured to produce an indication when the medicament delivery device transitions from the first configuration to the second configuration, the radio configured to send the second signal in response to the indication.

6. The apparatus of claim 5, wherein the sensor is at least one of a contact sensor, a switch, a microphone, a capacitance sensor or an optical sensor.

7. The apparatus of claim 1, wherein:

the electronic circuit system includes a sensor and a communication module, the communication module implemented in at least one of a memory or a processing device, the sensor configured to produce an indication when the medicament delivery device transitions from the first configuration to the second configuration, the communication module configured to determine, based on the transition information, the second communication interval.

8. The apparatus of claim 1, wherein:

the medicament delivery device is an auto-injector having an actuator configured to initiate delivery of a medicament and a lock member configured to limit movement of the actuator, the lock member in a first position relative to the actuator when the medicament delivery device is in the first configuration, the lock member in a second position relative to the actuator when the medicament delivery device is in the second configuration.

9. The apparatus of claim 1, wherein:

the medicament delivery device is configured to produce a sound when the medicament delivery device is transitioned from the first configuration to the second configuration;

the electronic circuit system includes a microphone configured to produce an indication in response to the sound; and

the radio is configured to send the second signal in response to the indication.

10. The apparatus of claim 1, further comprising:

an adapter configured to receive at least a portion the medicament delivery device, the electronic circuit system being coupled to the adapter,

the portion of the medicament delivery device being within the adapter when the medicament delivery device is in the first configuration, the portion of the medicament delivery device being outside of the adapter when the medicament delivery device is in the second configuration.

11. The apparatus of claim 1, wherein:

the electronic circuit system includes a sensor configured to produce an indication when the medicament delivery device transitions from the first configuration to the second configuration; and

the radio is configured to send a third signal to initiate a natural language user interface associated with the computing device in response to the indication.

12-26. -26. (canceled)

27. An apparatus, comprising:

a radio configured to electronically communicate with a computing device via a wireless protocol, the radio configured to send a first wireless signal associated with a first communication signal and a second wireless signal associated with a second communication signal;

a memory configured to store transition information associated with a transition of a medicament delivery device from a first configuration to a second configuration; and

a communication module implemented in at least one of the memory or a processing device, the communication module configured to receive the transition information and determine, based on the transition information, at least the second communication interval.

28. The method of claim 27, wherein the second communication interval is at least one of an advertising interval, a hold duration period, a sniff interval or a park mode beacon period.

29. The apparatus of claim 27, wherein:

the first communication interval is associated with a first communication mode between the radio and the computing device; and

the second communication interval is associated with a second communication mode between the radio and the computing device, the second communication mode different than the first communication mode.

30. The apparatus of claim 27, wherein:

the memory is configured to store actuation information associated with an actuation of the medicament delivery device; and

the communication module configured to receive the actuation information and produce, based on the actuation information, a data signal.

31. The apparatus of claim 30, wherein:

at least one of the first wireless signal or the second wireless signal is associated with a first radio frequency channel; and

the radio is configured to send a third wireless signal associated with the data signal produce, the third wireless signal associated with a second radio frequency channel, the second radio frequency channel different from the first radio frequency channel.

32-54. -54. (canceled)

55. A method, comprising:

receiving an indication associated with an operation from a plurality of operations associated with a simulated medicament delivery device;

producing, in response to the indication, a recorded speech output associated with a first training script;

updating, in response to the indication, use information associated with the plurality of operations associated with the simulated medicament delivery device; and

producing, in response to the updated use information, a second training script.

56. The method of claim 55, wherein the indication is a first indication received at a first time, the method further comprising:

receiving, at a second time, a second indication associated with the operation from the plurality of operations associated with the simulated medicament delivery device; and

producing, in response to the second indication, a recorded speech output associated with the second training script.

57. The method of claim 55, wherein the updating includes at least one of overwriting the use information stored in a memory or appending to the use information stored in the memory.

58. The method of claim 55, wherein the use information includes at least one of a time associated with the receiving the indication, a number of times the operation from the plurality of operations has been performed or a sequence associated with the plurality of operations.

59. The method of claim 55, wherein the operation from the plurality of operations include at least one of removing the simulated medicament delivery device from an adapter, removing a safety lock from the simulated medicament delivery device, orienting the simulated medicament delivery device or actuating the simulated medicament delivery device.

60. The method of claim 55, further comprising:

producing a wireless signal in response to the indication.

61. The method of claim 55, wherein the simulated medicament delivery device is configured to simulate any one of an auto-injector, a jet injector, a pen injector, a syringe, a nasal delivery device or an inhaler.

62. An apparatus, comprising:

an audible output device coupled to at least one of a medicament delivery device or a simulated medicament delivery device, the audible output device configured to produce an audible output associated with a first script in response to an operation from a plurality of operations associated with the medicament delivery device or the simulated medicament delivery device;

a memory configured to store use information associated with the plurality of operations; and

a use module implemented in at least one of the memory or a processing device, the use module configured to update, in response to the operation from the plurality of operations, use information associated with the plurality of operations, the use module configured to produce a second script based on the updated use information.

63. The apparatus of claim 62, further comprising;

a radio configured to electronically communicate with a computing device via a wireless protocol, the radio configured to send a wireless signal in response to the operation from the plurality of operations.

64. The apparatus of claim 62, wherein use information includes at least one of a time associated with the receiving the indication, a number of times the operation from the plurality of operations has been performed or a sequence associated with the plurality of operations.

65. The apparatus of claim 62, wherein:

the medicament delivery device is any one of an auto-injector, a jet injector, a pen injector, a bolus injector, a wearable pump, a patch pump, a wearable injector, a syringe, a nasal delivery device or an inhaler; and

the simulated medicament delivery device is configured to simulate the medicament delivery device and is devoid a medicament.

66-73. -73. (canceled)