System for Determining Position of Element

• US 20140243750A1
• Filed: 10/05/2012
• Published: 08/28/2014
• Est. Priority Date: 10/07/2011
• Status: Active Grant

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Larsen, Andre, Soerensen, Henrik Riehm, Olesen, Laurits Hoejgaard, Krusell, Nikolaj Frogner, Andersen, Jens Christian
• Granted Patent: US 10,155,090 B2
• Time in Patent Office: Days
• US Class Current: 604/189
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3389 Continuous level detection A61M2205/3393 takes precedence
• CPC Class Codes: A61M 2205/6054 Magnetic identification systems
• CPC Class Codes: A61M 2209/086 Docking stations
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31525 Dosing burettes, pipettes B01L3/02
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: G01B 7/30 for measuring angles or tapers; for testing the alignment of axes
• CPC Class Codes: G01D 18/004 Continuous recalibration
• CPC Class Codes: G01D 18/008 with calibration coefficients stored in memory
• CPC Class Codes: G01D 2205/22 by converting the rotary movement into a linear movement
• CPC Class Codes: G01D 5/145 influenced by the relative movement between the Hall device and magnetic fields see G01R33/06
• CPC Class Codes: G01R 33/0206 Three-component magnetometers

Abstract

System comprising a sensor assembly (3, 4, 5, 6) adapted to measure a magnetic field, and a moveable element (1) adapted to be moved relative to the sensor assembly between two positions by a combined axial and rotational movement, the rotational movement having a pre-determined relationship to the axial movement. A magnet (3) is mounted to the moveable element and configured to generate a spatial magnetic field which relative to the sensor assembly varies corresponding to both the axial and rotational movement of the magnet and thus the moveable element. A processor is configured to determine on the basis of measured values for the magnetic field an axial position of the moveable element.

Claims

1. A system comprising:

a sensor assembly comprising one or more sensors each adapted to measure a magnetic field corresponding to three axes,

a moveable element adapted to be moved relative to the sensor assembly by a combined axial and rotational movement corresponding to a pre-defined axis, the rotational movement having a pre-determined relationship to the axial movement,

a magnet mounted to the moveable element and moving together therewith, the magnet configured to generate a spatial magnetic field which relative to the sensor assembly varies corresponding to both the axial and rotational movement of the magnet and thus the moveable element, thereby generating a spatial magnetic field which varies uniquely relative to each sensor, and

a processor configured to determine on the basis of measured values an axial position of the moveable element.

2. A system as in claim 1, wherein the processor is configured to calculate differences between measured sensor values and expected sensor values, the determination of the axial position of the moveable element being based thereupon.

3. A system as in claim 2, further comprising memory in which a nominal representation of the system comprising a number of system parameters is stored, wherein the processor is adapted to, on the basis of differences between measured and expected sensor field values, determine the deviation of model fit and estimate which system parameters that causes the deviation.

4. A system as in claim 1, further comprising memory in which a nominal representation of the system comprising a number of system parameters is stored, the processor being configured to:

calculate for each sensor and each axis a difference between a measured sensor value and the expected nominal sensor value,

transform the difference into deviations of selected system parameters,

re-adjust the expected sensor values into corrected sensor values based on the system parameter deviations, and

determine an axial position of the moveable element being based on the calculated differences between the measured sensor values and the corrected sensor values.

5. A system as in claim 1, wherein the processor, on the basis of the measured values, is adapted to:

determine an initial axial position of the moveable element,

determine a rotational position of the moveable element, and

calculate a corrected axial position of the moveable element,

wherein the calculation is based on the determined initial axial position, the determined rotational position, and the pre-determined relationship between the rotational and the axial movement.

6. A system as in claim 1, wherein the sensor assembly is configured as one or more rings each consisting of two or more sensors placed around the pre-defined axis.

7. A system as in claim 1, wherein the magnet is an induced magnet.

8. A system as in claim 1, wherein the moveable element is moved corresponding to a threaded relationship between the moveable element and a further element.

9. A system as in claim 1, comprising a drug delivery device comprising:

a reservoir or structure for receiving a reservoir for a drug, the reservoir comprising an axially displaceable piston and an outlet, and

a drug expelling mechanism for expelling drug from the reservoir and comprising the moveable element in the form of a threaded piston rod which during an expelling action performs the combined axial and rotational movement thereby axially moving the piston of a mounted reservoir.

10. A system as in claim 9, comprising a measuring unit in which the sensor assembly and processor are arranged, and which is configured to receive the drug delivery device in a pre-determined position, the measuring unit being configured to calculate the size of an expelled dose of drug based on two consecutive determinations of the axial position of the piston rod.

11. A system as in claim 10, wherein the measuring unit is in the form of a cap unit adapted to calculate the size of an expelled dose of drug when the cap unit is placed in its mounted position on the drug delivery device to cover the outlet of a mounted reservoir.

12. A system as in claim 9, comprising a measuring assembly in which the sensor assembly and processor are arranged, the measuring assembly comprising a measuring unit and a cap unit,

wherein the measuring unit comprises the sensor assembly as well as coupling structure allowing the measuring unit to be mounted on the drug delivery device with the sensor assembly in a pre-determined position relative to the piston rod, and

wherein the cap unit is configured to be releasably mounted on the drug delivery device or the measuring unit to cover the outlet of a mounted reservoir.

13. A system as in claim 9, comprising a display controlled by the processor to display a calculated dose of drug.

14. A system as in claim 10, the drug delivery device further comprising:

an identifier representing information for the specific drug type contained in the reservoir or the specific drug delivery device,

the measuring unit further comprising;

structure for capturing information from the identifier,

logging structure adapted to create a log for amounts of drug expelled from the reservoir based on calculated doses of drug, the log being created for a given identifier.

15. A system as in claim 14, wherein the identifier is a colour, in the form of a barcode, or in the form of a pattern of conductive elements.

16. A drug delivery system, comprising:

a drug delivery device comprising;

a reservoir containing a drug,

a drug expelling mechanism for expelling drug from the reservoir, and

an identifier representing information for the specific drug type contained in the reservoir or the specific drug delivery device,

a capture assembly releasably mountable on the drug delivery device, comprising;

an electronically controlled capturing system for capturing data representing a property related to the amount of drug expelled from the reservoir by the expelling structure,

electronically controlled structure for capturing information from the identifier,

logging structure adapted to create a log for amounts of drug expelled from the reservoir based on captured data,

wherein the log is created for a given identifier.

17. A drug delivery system as in claim 16, wherein the identifier represents a given specific type of drug.

18. A drug delivery system as in claim 16, wherein the identifier represents a given unique drug delivery device.

19. A drug delivery system as in claim 16, wherein the identifier is a colour.

20. A drug delivery system as in claim 16, wherein the identifier is in the form of a barcode.

21. A drug delivery system as in claim 16, wherein the identifier is the form of a pattern of conductive elements.

22. A drug delivery system as in claim 20, wherein the structure for capturing information from the identifier comprises a sensor adapted to capture information during movement of the sensor relative to the identifier.

23. A drug delivery system as in claim 22, wherein the drug delivery device and the capture assembly comprises corresponding releasable mounting structure adapted to mount the capture device in a pre-defined position relative to the drug delivery device, the mounting requiring a specified translational movement between the drug delivery device and the capture assembly, the translational movement allowing the sensor to capture information from the identifier.

24. A drug delivery system as in claim 16, wherein the system comprises at least two drug delivery devices, each comprising a unique identifier.